Yazar "Yazıcı, Zihni Açar" için listeleme
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Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus
Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Şahin, Zafer; Akyıldız, Kerimali; Karataş, Kader Semra; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar (Elsevier, 2023)Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side ef-fects, including cognitive impairment. Agomelatine, a synthetic melatonin analogue, is an important antide-pressant. ... -
Anthocyanins profiling of Thymus praecox opiz subsp caucasicus var. caucasicus
Turumtay, Emine Akyüz; Turumtay, Halbay; Demir, Adem; Selvi, Emine Kılıçkaya; Yazıcı, Emre; Sandallı, Cemal; Yazıcı, Zihni Açar (Elsevier Science Bv, 2015)Thymus praecox Opiz subsp. caucasicus var. caucasicus (Anzer tea) was studied to determine its anthocyanin content; anthocyanin stability in response to acidic hydrolysis and temperature changes. in this study, anthocyanin ... -
Antiproliferative effect of ornithogalum balansae on human cancer cell lines
Ejder, Nebahat; Ekşi, Saliha; Yazıcı, Zihni Açar; Beriş, Fatih Şaban; Makbul, Serdar; Uzunok, Barış (Indian Pharmaceutical Assoc, 2020)The purpose of this study was to investigate the antiproliferative effect of the methanol and ethyl acetate extracts of Ornithogalum balansae flower and bulb against normal ARPE-19 cell line and cancer cell lines, A549, ... -
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Akyıldız, Kerimali; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar; Yılmaz, Adnan (Elsevier, 2021)It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ... -
Chitosan-coated scorpion venom ameliorates acute lung injury caused by klebsiella pneumoniae
Oskay, Burak; Şahin, Kazım; Çalışkan, Figen; Mercantepe, Tolga; Aktura, Sena Şahin; Tümkaya, Levent; Topçu, Atilla; Yılmaz, Adnan; Karakaş, Sibel Mataracı; Yazıcı, Zihni Açar (Springer, 2024)Nosocomial infections caused by antibiotic-resistant bacteria result in significant economic costs and human health issues, including acute lung injury. The purpose of this study was to investigate the scorpion venom in ... -
Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus
Tekin, Yeşim Bayoğlu; Güven, Emine Seda Güvendağ; Yazıcı, Zihni Açar; Kırbaş, Aynur; Kır, Figen Şahin (2014)AMAÇ: Bu çalışmanın amacı Cooper T ve Levonorgestrelli Rahim içi araçların (LNG-IUD) servikal mukus proteoglikan yapısı üzerine etkisinin değerlendirilmesidir. GEREÇ VE YÖNTEM: Bu kesitsel çalışma bir üniversite hastanesi ... -
Contribution of neutrophil activation in the differentiation of urine infection and contamination in pregnant women
Şahin, Kazım; Dilek, Aziz Ramazan; Güven, Emine Seda Güvendağ; Yazıcı, Zihni Açar (Karger, 2015)Background: Urinary tract infections are among the most common bacterial infections of humans. Urine culture is the gold standard for asymptomatic bacteriuria and pyuria is not always present in bacteriuria, nor is it ... -
Correlation of suicidal thoughts and toxoplasmosis in patients with depression
Bahçeci, İlkay; Bahçeci, Bülent; Şentürk, Şenol; Yıldız, İlknur Esen; Yazıcı, Zİhni Açar (Cureus Inc., 2021)Objective We investigated the correlation between serum anti-Toxplasma gondii IgG and suicidal thoughts in depressive patients. Methods Depressive patients with (n = 100) and without (n = 100) suicidal thoughts ... -
COVID-19 vaccine immunity in oncology patients
Uslu, Gonca Hanedan; Rakıcı, Sema Yılmaz; Çiçek, Ayşegül Çopur; Yazıcı, Zihni Açar (AEPRESS Sro, 2023)BACKGROUND: To investigate the effect of vaccine types applied in our country against 2019 coronavirus disease on the formation of protective antibodies in oncology patients. MATERIALS AND METHODS: The data of 81 cancer ... -
Effect of the prenatal electromagnetic field exposure on cochlear nucleus neurons and oligodendrocytes in rats
Tümkaya, Levent; Baş, Orhan; Mercantepe, Tolga; Çınar, Seda; Özgür, Abdulkadir; Yazıcı, Zihni Açar (Springer Heidelberg, 2022)Electromagnetic radiation from elecromagnetic field (EMF) sources has been an important health concern for a long time. The vast majority of this exposure is due to the widespread use of mobile phones, an important source ... -
Effects of gadodiamide and gadoteric acid on lung tissue: A comparative study
Çeliker, Fatma Beyazal; Tümkaya, Levent; Suzan, Zehra T.; Topçu, Atilla; Mercantepe, Tolga; Çınar, Seda; Yazıcı, Zihni Açar; Yılmaz, Adnan (Wiley, 2022)We set out to investigate the effects of gadodiamide and gadoteric acid, used for magnetic resonance imaging, on the lungs. In this study, 32 male Sprague Dawley rats were used. These were allocated into four groups; The ... -
The effects of mobile phone exposure on mast cells in rat dura mater
Tümkaya, Levent; Kalkan, Yıldıray; Gökçe, Fatih Mehmet; Erdivanlı, Başar; Yılmaz, Adnan; Bahçeci, İlkay; Yazıcı, Zihni Açar; Mercantepe, Tolga (Soc Chilena Anatomia, 2019)Mobile phone use has increased rapidly. the central nervous system has been shown to be adversely affected by its electromagnetic field (EMF) resulting in headache and sleep disturbances. How the cells make up the CNS and ... -
Evaluation of some biochemical and complete blood count parameters in pregnant women with COVID-19
Kağıtcı, Mehmet; Bahçeci, İlkay; Yazıcı, Zihni Açar; Kazdal, Hızır; Dereci Delibaş, Deniz; Kuruca, Nalan; Yılmaz, Bülent (Ege Üniversitesi, 2024)Aim: Prediction of severity of COVID 19 infection in pregnant population is very important to management. The aim of this study was to investigate the relationship between COVID 19 infection severity and routine ... -
Factors affecting mortality at home and hospital in oncology patients and the effect of age
Rakıcı, Sema Yılmaz; Terzi, Özlem; Özyurt, Songül; Yazıcı, Zihni Açar (Turkiye Klinikleri, 2024)Objective: Several factors assessing cancer mortality and impacting the choice of place of death for terminally ill patients have been previously documented. We examined the relationships between several oncological factors, ... -
Glass particle contamination threat in nursing practice: A pilot study
Erkoç Hut, Arzu; Yazıcı, Zihni Açar (Wiley, 2021)Aim The aim of this study was to determine the level of glass particle contamination from medical ampoules during breakage in nursing practice and their removal by filtration. Design Glass medical ampoules were broken-open ... -
Identification of the potential matrix protein of invertebrate iridescent virus 6 (IIV6)
Gencer, Dönüş; Yeşilyurt, Aydın; Özşahin, Emine; Muratoğlu, Hacer; Yazıcı, Zihni Açar; Demirbağ, Zihni; Nalcacıoğlu, Remziye (Elsevier, 2023)Invertebrate iridescent virus 6 (IIV6) is a nucleocytoplasmic virus with a similar to 212 kb linear dsDNA genome that encodes 215 putative open reading frames (ORFs). Proteomic analysis has revealed that the IIV6 virion ... -
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab
Bahçeci, İlkay; Tümkaya, Levent; Mercantepe, Tolga; Aslan, Nuray; Duran, Ömer Faruk; Söztanacı, Umut Serkan; Yazıcı, Zihni Açar (Taylor & Francis Ltd., 2022)Methotrexate (MTX) has been in use for the treatment of rheumatoid arthritis (RA), psoriasis, and cancer since 1948. Its toxic side effects on tissues and organs have been well documented but splenotoxicity has not been ... -
Lasting hepatotoxic effects of prenatal mobile phone exposure
Yılmaz, Adnan; Tümkaya, Levent; Akyıldız, Kerimali; Kalkan, Yıldıray; Bodur, Ali Fuat; Sargın, Fatma; Efe, Hasan; Uydu, Hüseyin Avni; Yazıcı, Zihni Açar (Taylor & Francis Ltd, 2017)Objective: in this study, the livers of rats born to mothers exposed to electromagnetic field (EMF) were examined 60 days postpartum for biochemical and histopathological changes.Methods: Pregnant rats were exposed to ... -
Lymphocyte subpopulations in Sheehan's syndrome
Atmaca, Hulusi; Araslı, Mehmet; Yazıcı, Zihni Açar; Armutçu, Ferah; Tekin, İshak Özel (Springer, 2013)The role of autoimmunity in the development of Sheehan's syndrome is obscure. There are a limited number of studies investigating the immunological alterations accompanying Sheehan's Syndrome. Our objective was to evaluate ... -
Marine-Lenhart syndrome with papillary thyroid carcinoma
Atmaca, Hulusi; Çolak, Ramis; Yazıcı, Zihni Açar; Kefeli, Mehmet; Tosun, Fevziye Canbaz (Medknow Publications & Media Pvt Ltd, 2015)Graves' disease with accompanying functioning nodules is known as Marine-Lenhart syndrome. Autonomously functioning thyroid nodules (AFTNs) also within Graves' thyroid tissue are almost always bening in nature. A 45-year-old ...
