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Küçük Resim

Effect of 900-MHz electromagnetic field on the cerebellum: a histopathological investigation 

Mercantepe, Tolga; Tümkaya, Levent; Gökçek, Mehmet Fatih; Suzan, Zehra Topal; Esmer, Erva (2018)
Objectives: The currently widely used technological devices give rise to electromagnetic fields (EMFs) at various frequencies. Recent studies have reported that EMFs damage the central nervous system. The cerebellum is of ...
Küçük Resim

Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity 

Mercantepe, Tolga; Kalkan, Yıldıray; Tümkaya, Levent; Şehitoğlu, İbrahim; Mercantepe, Filiz; Yıldırmış, Sermet (Wroclaw Medical Univ, 2018)
Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ...
Küçük Resim

Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury 

Mercantepe, Filiz; Mercantepe, Tolga; Topçu, Atilla; Yılmaz, Adnan; Tümkaya, Levent (Springer, 2018)
Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ...
Küçük Resim

Effects of gadolinium-based contrast agents on submandibular gland tissue in rats 

Çeliker, Fatma Beyazal; Tümkaya, Levent; Yılmaz, Adnan; Coşkun, Zerrin Özergin; Çeliker, Metin; Oğhan, Fatih; Mercantepe, Tolga; Terzi, Suat; Dursun, Engin (Springer, 2018)
The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on ...
Küçük Resim

Protective effects of amifostine, curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damage in rats 

Mercantepe, Tolga; Ünal, Deniz; Tümkaya, Levent; Yazıcı, Zihni Açar (Spandidos Publ Ltd, 2018)
Cisplatin is an effective antineoplastic drug that is usually used to treat a number of different types of cancer in the clinic. One of the most notable side effects of cisplatin use is infertility. the present study was ...
Küçük Resim

A novel therapeutics agent: antioxidant effects of hydroxylfasudil on rat kidney and liver tissues in a protamine sulphate-induced cystitis rat model; preliminary results 

Bozkurt, Aliseydi; Budak, Harun; Erol, Hüseyin Serkan; Can, Serpil; Mercantepe, Tolga; Akın, Yiğit; Özbey, İsa; Çankaya, Murat; Halıcı, Mesut Bünyamin; Çoban, T. Abdülkadir (Taylor & Francis Ltd, 2018)
Cystitis is defined as an inflammation of the bladder caused by a bacterial infection, and it can be dangerous and painful when it spreads through the internal organs. in this study, antioxidant effects of hydroxylfasudil ...
Küçük Resim

Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats 

Kaya, Habibe Budak; Polat, Beyzagül; Albayrak, Aabdulmecit; Mercantepe, Tolga; Büyük, Başak (Sage Publications Ltd, 2018)
Paracetamol (P), one of the most popular and commonly used analgesic and antipyretic agents, causes hepatotoxicity in overdoses. Amlodipine (AML), an L-type calcium channel blocker, has been shown to have anti-inflammatory ...
Küçük Resim

Effects of gadolinium-based MRI contrast agents on liver tissue 

Mercantepe, Tolga; Tümkaya, Levent; Çeliker, Fatma Beyazal; Suzan, Zehra Topal; Çınar, Seda; Akyıldız, Kerimali; Mercantepe, Filiz; Yılmaz, Adnan (Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...
Küçük Resim

Whortleberry protects kidney against the cisplatin-induced nephrotoxicity: an experimental study 

Eren, Hüseyin; Aydın, Hasan Rıza; Tümkaya, Levent; Kazaz, İlke Onur; Kalkan, Yıldıray; Kazaz, Seher Nazlı; Mercantepe, Tolga; Horsanali, Mustafa Ozan; Yılmaz, Adnan (Taylor & Francis Ltd, 2018)
Purpose: This study investigated the antioxidant effects of whortleberry against cisplatin-induced nephrotoxicity in rats.Material and methods: This study included 48 female Sprague-Dawley rats weighing 263.688.29g. the ...
Küçük Resim

Pathological findings observed in the kidneys of postnatal male rats exposed to the 2100 MHz electromagnetic field 

Bedir, Recep; Tümkaya, Levent; Mercantepe, Tolga; Yılmaz, Adnan (Elsevier Science Inc, 2018)
Background. the widespread use by young people of modern communication devices such as mobile phones means that they are particularly exposed to electromagnetic fields (EMF) and other problems. However, few studies have ...
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Mercantepe, Tolga (16)
Tümkaya, Levent (13)Yılmaz, Adnan (8)Mercantepe, Filiz (4)Suzan, Zehra Topal (3)Çeliker, Fatma Beyazal (3)Eren, Hüseyin (2)Esmer, Erva (2)Horsanali, Mustafa Ozan (2)Kalkan, Yıldıray (2)... Daha FazlaAnahtar KelimeRat (5)Cisplatin (4)Kidney (3)Testis (3)Amifostine (2)Apoptosis (2)Curcumin (2)Electromagnetic field (2)Gadolinium (2)Liver (2)... Daha FazlaYayın Tarihi
2018 (16)
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