Basit öğe kaydını göster

dc.contributor.authorBayoğlu Tekin, Yeşim
dc.contributor.authorBaki Erin, Kübra
dc.contributor.authorYılmaz, Adnan
dc.date.accessioned2020-12-19T19:34:40Z
dc.date.available2020-12-19T19:34:40Z
dc.date.issued2020
dc.identifier.citationBayoglu Tekin, Y., Baki Erin, K., & Yilmaz, A. (2020). Evaluation of SCUBE-1 levels as a placental dysfunction marker at gestational diabetes mellitus. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 36(5), 417–420. https://doi.org/10.1080/09513590.2019.1683537en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.urihttps://doi.org/10.1080/09513590.2019.1683537
dc.identifier.urihttps://hdl.handle.net/11436/1144
dc.descriptionWOS: 000531711900008en_US
dc.descriptionPubMed: 31668102en_US
dc.description.abstractObjective: To evaluate the alteration of plasma levels of signal peptide-CUB-EGF domain-containing protein (SCUBE)-1 as a marker of endothelial dysfunction and vascular injury in gestational diabetes mellitus (GDM) in comparison to healthy pregnant controls. Methods: A prospective study conducted at an antenatal outpatient clinic of a University hospital. Fifty pregnancies with GDM and thirty healthy pregnancies as controls were enrolled in the study. Results: There was no statistically significant difference between the groups in terms of age, gravidity, weight and BMI from pre-pregnancy until delivery, total weight gain, fetal weight and other hematological and biochemical parameters. SCUBE-1 levels were significantly higher in GDM patients (p = .007). Conclusions: Hyperglycemia predisposes to endothelial injury and vascular remodeling at GDM, and therefore, SCUBE-1 could be a predictor of vascular injury during pregnancy. Our study is the first to illustrate increased SCUBE-1 levels in GDM as a marker of placental endothelial dysfunction.en_US
dc.language.isoengen_US
dc.publisherTaylor & Francis Ltden_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSCUBE-1en_US
dc.subjectGestational diabetes mellitusen_US
dc.subjectPregnancyen_US
dc.subjectPlacentaen_US
dc.subjectEndothelial dysfunctionen_US
dc.titleEvaluation of SCUBE-1 levels as a placental dysfunction marker at gestational diabetes mellitusen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorYılmaz, Adnan
dc.identifier.doi10.1080/09513590.2019.1683537
dc.identifier.volume36en_US
dc.identifier.issue5en_US
dc.identifier.startpage417en_US
dc.identifier.endpage420en_US
dc.relation.journalGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster