| dc.contributor.author | Ünver, Yasemin | |
| dc.contributor.author | Tuluk, M. | |
| dc.contributor.author | Kahriman, Nuran | |
| dc.contributor.author | Emirik, Mustafa | |
| dc.contributor.author | Bektaş, Ersan | |
| dc.contributor.author | Direkel, Şahin | |
| dc.date.accessioned | 2020-12-19T19:40:30Z | |
| dc.date.available | 2020-12-19T19:40:30Z | |
| dc.date.issued | 2019 | |
| dc.identifier.citation | Ünver, Y., Tuluk, M., Kahriman, N., Emirik, M., Bektaş, E. & Direkel, Ş. (2019). New Chalcone Derivatives with Schiff Base-Thiophene: Synthesis, Biological Activity, and Molecular Docking Studies. Russian Journal of General Chemistry, 89(4), 794-799. https://doi.org/10.1134/S107036321904025X | en_US |
| dc.identifier.issn | 1070-3632 | |
| dc.identifier.issn | 1608-3350 | |
| dc.identifier.uri | https://doi.org/10.1134/S107036321904025X | |
| dc.identifier.uri | https://hdl.handle.net/11436/1558 | |
| dc.description | emirik, mustafa/0000-0001-9489-9093; | en_US |
| dc.description | WOS: 000469246900025 | en_US |
| dc.description.abstract | New thiophene chalcones 3, 6 and thiophene Schiff base-chalcone derivatives 4a-4d, 7a-7d are synthesized. Structures of the compounds are confirmed by H-1 and C-13 NMR, and IR spectra. According to antimicrobial and antileishmanial tests, the compounds 4c-7c demonstrate efficient antileishmanial and antimicrobial activities. Molecular docking studies based on Maestro Molecular Modeling indicate 4c and 7c to be the most potent compounds that are characterized by the least docking score,-10.674 and-10.989 kcal/mol, respectively. | en_US |
| dc.description.sponsorship | Karadeniz Technical UniversityKaradeniz Technical University [KTU BAP 7222] | en_US |
| dc.description.sponsorship | This study was supported by grants from Karadeniz Technical University (KTU BAP 7222). | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Maik Nauka/Interperiodica/Springer | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Chalcone | en_US |
| dc.subject | Schiff base | en_US |
| dc.subject | Thiophene | en_US |
| dc.subject | Molecular docking | en_US |
| dc.subject | Antileishmanial and antimicrobial activity | en_US |
| dc.title | New chalcone derivatives with Schiff base-thiophene: Synthesis, biological activity, and molecular docking studies | en_US |
| dc.type | article | en_US |
| dc.contributor.department | RTEÜ, Fen - Edebiyat Fakültesi, Kimya Bölümü | en_US |
| dc.contributor.institutionauthor | Emirik, Mustafa | |
| dc.identifier.doi | 10.1134/S107036321904025X | |
| dc.identifier.volume | 89 | en_US |
| dc.identifier.issue | 4 | en_US |
| dc.identifier.startpage | 794 | en_US |
| dc.identifier.endpage | 799 | en_US |
| dc.relation.journal | Russian Journal of General Chemistry | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
