dc.contributor.author | Cüre, Medine Cumhur | |
dc.contributor.author | Cüre, Erkan | |
dc.contributor.author | Yüce, Süleyman | |
dc.contributor.author | Yazıcı, Tarkan | |
dc.contributor.author | Karakoyun, İnanç | |
dc.contributor.author | Efe, Hasan | |
dc.date.accessioned | 2020-12-19T20:03:22Z | |
dc.date.available | 2020-12-19T20:03:22Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Cure, M.C., Cure, E., Yuce, S., Yazici, T., Karakoyun, I., Efe, H., (2014). Mean Platelet Volume and Vitamin D Level. Annals of Laboratory Medicine, 34(2), 98-103. https://doi.org/10.3343/alm.2014.34.2.98 | |
dc.identifier.issn | 2234-3806 | |
dc.identifier.issn | 2234-3814 | |
dc.identifier.uri | https://doi.org/10.3343/alm.2014.34.2.98 | |
dc.identifier.uri | https://hdl.handle.net/11436/3152 | |
dc.description | Cure, Medine Cumhur/0000-0001-9253-6459; cure, erkan/0000-0001-7807-135X | en_US |
dc.description | WOS: 000332681100003 | en_US |
dc.description | PubMed: 24624344 | en_US |
dc.description.abstract | Background: Vitamin D deficiency and a high mean platelet volume (MPV) are related to cardiovascular disease. We investigated whether vitamin D deficiency is associated with high MPV. Methods: This study included 434 patients without chronic disease who were not taking vitamin D or calcium supplements. Vitamin D was measured by chemiluminescent microparticle immunoassay on the Architect-I2000 system (Abbott Diagnostics, USA), and MIN was measured on the Cell-Dyn Ruby analyzer (Abbott Diagnostics). Patients were divided into Groups 1 (138 [men/women, 46/92]), 2 (148 [men/women, 54/94]), and 3 (148 [men/women, 50/98]) according to vitamin D levels of <10 ng/mL, 10-20 ng/mL, and >20 ng/mL, respectively. Results: the vitamin D level in Group 1 (7.7 +/- 1.9 ng/mL) was lower than that in Group 2 (15.1 +/- 1.6 ng/mL, P<0.001) and Group 3 (25.6 +/- 6.3 ng/mL, P<0.001). the MPV in Group 3 (7.5 +/- 1.0 fL) was lower than that in Group 1 (8.1 +/- 1.1 fL, P<0.001) and Group 2 (7.9 +/- 1.0 fL, P=0.009). Linear regression analysis showed that low levels of vitamin D (beta = -0.109, P = 0.019) was independently associated with increased MPV. Conclusions: There was a strong association between a low vitamin D level and a high MPV; therefore, vitamin D deficiency may be associated with increased MPV. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Korean Soc Laboratory Medicine | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Vitamin D | en_US |
dc.subject | Deficiency | en_US |
dc.subject | Mean platelet volume | en_US |
dc.subject | Cardiovascular diseases | en_US |
dc.title | Mean platelet volume and vitamin D level | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Cüre, Medine Cumhur | |
dc.contributor.institutionauthor | Cüre, Erkan | |
dc.contributor.institutionauthor | Yüce, Süleyman | |
dc.contributor.institutionauthor | Yazıcı, Tarkan | |
dc.contributor.institutionauthor | Efe, Hasan | |
dc.identifier.doi | 10.3343/alm.2014.34.2.98 | |
dc.identifier.volume | 34 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 98 | en_US |
dc.identifier.endpage | 103 | en_US |
dc.ri.edit | oa | en_US |
dc.relation.journal | Annals of Laboratory Medicine | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |