dc.contributor.author | Uydu, Hüseyin Avni | |
dc.contributor.author | Bostan, Mehmet | |
dc.contributor.author | Yılmaz, A. | |
dc.contributor.author | Demir, Adem | |
dc.contributor.author | Atak, Mehtap | |
dc.contributor.author | Şaturoğlu, Ömer | |
dc.contributor.author | Temiz, A. | |
dc.contributor.author | Çiçek, Yağız Anıl | |
dc.contributor.author | Erdoğan, Turan | |
dc.contributor.author | Çetin, Mustafa | |
dc.contributor.author | Canga, Aranzazu Gonzalez | |
dc.date.accessioned | 2020-12-19T20:04:59Z | |
dc.date.available | 2020-12-19T20:04:59Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Uydu, HA., Bostan, M., Yılmaz, A., Demir, A., Atak, M., Şatıroğlu, O., Temiz, A. ve diğerleri. (2013). Comparison of inflammatory biomarkers for detection of coronary stenosis in patients with stable coronary artery disease. European Review For Medical and Pharmacological Sciences, 17(1), 112-118. | en_US |
dc.identifier.issn | 1128-3602 | |
dc.identifier.uri | https://hdl.handle.net/11436/3390 | |
dc.description | Erdogan, Turan/0000-0003-2986-5457; Cetin, Mustafa/0000-0001-6342-436X; yilmaz, adnan/0000-0003-4842-1173 | en_US |
dc.description | WOS: 000319223400015 | en_US |
dc.description | PubMed: 23329531 | en_US |
dc.description.abstract | BACKGROUND: the objective of the current study was to evaluate the role of various inflammatory biomarkers in detection of coronary stenosis in patients with stable coronary artery disease (CAD) and healthy people. METHODS: A total of 111 patients with stable coronary artery disease, and 66 healthy subjects were enrolled in the study. Serum levels of lipoprotein-associated-phospholipase A2 (Lp-PLA(2)), high-sensitivity C-reactive protein (hs-CRP), and myeloperoxidase (MPO) were measured to compare patient and control groups. RESULTS: Baseline characteristics were similar between healthy and patient groups, with the exception of age. ANCOVA and log-transformed data of inflammatory biomarkers revealed that, Lp-PLA(2) (p < 0,001) and hs-CRP (p < 0,05) levels in all patient groups were significantly higher than in the control group. Conversely, there was no significant difference in MPO levels among groups. CONCLUSIONS: in stable CAD patients, serum Lp-PLA(2) levels are more compatible than hsCRP and MPO levels in the detection of coronary stenosis. | en_US |
dc.description.sponsorship | PfizerPfizer; ServierServier; Astra ZenecaAstraZeneca | en_US |
dc.description.sponsorship | This study was supported by the drug companies Pfizer, Servier and Astra Zeneca. the Authors thank all of the companies that helped during this investigation. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Verduci Publisher | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Coronary Artery Disease | en_US |
dc.subject | Lp-PLA(2) | en_US |
dc.subject | MPO | en_US |
dc.subject | hsCRP | en_US |
dc.title | Comparison of inflammatory biomarkers for detection of coronary stenosis in patients with stable coronary artery disease | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
dc.identifier.volume | 17 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 112 | en_US |
dc.identifier.endpage | 118 | en_US |
dc.relation.journal | European Review For Medical and Pharmacological Sciences | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |