dc.contributor.author | Fandaklı, Seda | |
dc.contributor.author | Korkmaz, Büşra | |
dc.contributor.author | Faiz, Özlem | |
dc.contributor.author | Kılıç, Gözde | |
dc.contributor.author | Erik, İshak | |
dc.contributor.author | Terzioğlu, Salih | |
dc.contributor.author | Yaylı, Nurettin | |
dc.date.accessioned | 2022-10-12T10:53:06Z | |
dc.date.available | 2022-10-12T10:53:06Z | |
dc.date.issued | 2021 | en_US |
dc.identifier.citation | Fandakli, S., Korkmaz, S., Faiz, O., Kilic, G., Erik, I., Terzioglu, S. & Yayli, N. (2021). Chemical Variation, Antimicrobial, Nitric Oxide Scavenging Activities and Tyrosinase Inhibition of Essential Oils and Solvent Extracts from Filipendula vulgaris Moench Growing in Turkey. Iranian Journal Pharmaceutical Reseaarch, 20(3), 110-120. https://doi.org/10.22037/ijpr.2021.114302.14786 | en_US |
dc.identifier.issn | 1735-0328 | |
dc.identifier.issn | 1726-6890 | |
dc.identifier.uri | https://doi.org/10.22037/ijpr.2021.114302.14786 | |
dc.identifier.uri | https://hdl.handle.net/11436/6728 | |
dc.description.abstract | Volatile organic compositions of the essential oils (EOs), solid-phase microextraction (SPME) and SPME of n-hexane extracts from the flower and stem-leaf of Filipendula vulgaris (F. vulgaris) were analyzed by GC-FID/MS. A total of 107 constituents were characterized, flower and stem leaf parts of the plant were found to contain different volatile organic compounds. Tricosane (29.6%), n-nonanal (20.5%) were identified as the main components in the essential oil of the flower, while phytol (35.2%) was found to be a major constituent in the essential oil of stem-leaf. Benzaldehyde (56.0%) and n-nonanal (31.6%) were the major groups in the SPME of stem-leaf and flower, respectively. The volatiles for the SPME of n-hexane extracts of the flower and stem leaf of F. vulgaris were predominated by aromatic compounds (75.0% and 78.5%) and ketones (18.1% and 10.1%), respectively. On the other hand, a total of terpene compounds was found at the most in the EO of the stem-leaf part of the plant (48.6%). In addition, antimicrobial, tyrosinase inhibition, and nitric oxide scavenging activities of the n-hexane (H), methanol (M), aqueous extracts (A) and EOs of F. vulgaris were investigated. EOs and methanol extracts of flower and stem-leaf had high antimicrobial activity against tested various microorganisms. However, n-hexane extracts of the flower and stem-leaf only displayed activity against Mycobacterium smegmatis. Methanol extracts of flower and stem-leaf possessed the best tyrosine inhibition and NO scavenging activity. | en_US |
dc.description.sponsorship | Karadeniz Technical University Research Fund KTU-BAP-6714 | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Shaheed Beheshti University | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Filipendula vulgaris | en_US |
dc.subject | Essential oil | en_US |
dc.subject | GC-FID | en_US |
dc.subject | MS | en_US |
dc.subject | SPME | en_US |
dc.subject | Biological activity | en_US |
dc.title | Chemical variation, antimicrobial, nitric oxide scavenging activities and tyrosinase inhibition of essential oils and solvent extracts from filipendula vulgaris moench growing in Turkey | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Fen - Edebiyat Fakültesi, Kimya Bölümü | en_US |
dc.contributor.institutionauthor | Faiz, Özlem | |
dc.identifier.doi | 10.22037/ijpr.2021.114302.14786 | en_US |
dc.identifier.volume | 20 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 110 | en_US |
dc.identifier.endpage | 120 | en_US |
dc.relation.journal | Iranian Journal Pharmaceutical Reseaarch | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |