Kurum Yazarı "Özil, Musa" WoS İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Binuclear Cu(II), Ni(II) and Zn(II) complexes of hydrazone Schiff bases: Synthesis, spectroscopy, DFT calculations, and SOD mimetic activity
Zengin, Ali; Serbest, Kerim; Emirik, Mustafa; Özil, Musa; Menteşe, Emre; Faiz, Özlem (Elsevier, 2023)Two new salicylaldimine-based N-heterocyclic hydrazone ligands, N'-[(2-hydroxyphenyl) methylene]2-(2-phenyl-1H-benzimidazol-1-yl)acetohydrazone (H 2 L 1 ) and 2-[2-(3-chlorobenzyl)-1H-benzimidazol-1yl]-N'-[(2-(hydroxyimi ... -
Bioevaluation of synthetic pyridones as dual inhibitors of alpha-amylase and alpha-glucosidase enzymes and potential antioxidants
Saleem, Faiza; Khan, Khalid Mohammed; Ullah, Nisar; Özil, Musa; Baltaş, Nimet; Hameed, Shehryar; Salar, Uzma; Wadood, Abdul; Rehman, Ashfaq Ur; Kumar, Mukesh; Taha, Muhammad; Haider, Syed Moazzam (Wiley, 2022)Herein, a library of novel pyridone derivatives 1-34 was designed, synthesized, and evaluated for alpha-amylase and alpha-glucosidase inhibitory as well as antioxidant activities. Pyridone derivatives 1-34 were synthesized ... -
Ecofriendly solventless synthesis and reduction reaction of some triazole compounds and evaluation of their antimicrobial activity
Özil, Musa; Menteşe, Emre; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Taylor & Francis Inc, 2013)A number of triazole-3-one compounds have been synthesized, and reduction of the carbonyl group in the molecule has been carried out to give a corresponding hydroxyl group that possesses asymmetric carbon atom in good ... -
Efficient synthesis of 5-(substituted)benzyl-2,4-dihydro-3H-1,2,4-triazol- 3-ones using microwave irradiation
A growing body of literature has shown the effectiveness of using microwave irradiation in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new 5-aryl-2,4-dihydro-3H-1,2,4- ... -
An efficient synthesis of benzimidazoles via a microwave technique and evaluation of their biological activities
Kahveci, Bahittin; Menteşe, Emre; Özil, Musa; Ülker, Serdar; Ertürk, Murat (Springer Wien, 2013)A simple and practical protocol was developed for the synthesis of benzimidazoles. the protocol uses iminoester hydrochloride which is very useful in the reaction with 4,5-dichloro-1,2-phenylenediamine under microwave ... -
Efficient, rapid, and high-yield synthesis of aryl Schiff base derivatives and their in vitro and in silico inhibition studies of hCA I, hCA II, AChE, and BuChE
Özil, Musa; Balaydın, Halis T.; Doğan, Berna; Şentürk, Murat; Durdağı, Serdar (Wiley, 2024)This study reports a rapid and efficient synthesis of four novel aryl Schiff base derivatives. Biological activity and molecular modeling studies were conducted to evaluate the inhibitory effects of these compounds on human ... -
Emerging glyco-based strategies to steer immune responses
Anderluh, Marko; Berti, Francesco; Bzducha-Wrobel, Anna; Chiodo, Fabrizio; Colombo, Cinzia; Compostella, Federica; Durlik, Katarzyna; Ferhati, Xhenti; Holmdahl, Rikard; Jovanovic, Dragana; Kaca, Wieslaw; Lay, Luigi; Marinovic-Cincovic, Milena; Marradi, Marco; Özil, Musa; Polito, Laura; Reina-Martin, Jose Juan; Reis, Celso A.; Sackstein, Robert; Silipo, Alba; Svajger, Urban; Vanek, Ondrej; Yamamoto, Fumiichiro; Richichi, Barbara; van Vliet, Sandra J. (Wiley, 2021)Glycan structures are common posttranslational modifications of proteins, which serve multiple important structural roles (for instance in protein folding), but also are crucial participants in cell-cell communications and ... -
Hydrazinyl thiazole linked indenoquinoxaline hybrids: Potential leads to treat hyperglycemia and oxidative stress; Multistep synthesis, alpha-amylase, and antioxidant activities
Hameed, Shehryar; Khan, Khalid Mohammed; Salar, Uzma; Özil, Musa; Baltaş, Nimet; Saleem, Faiza; Qureshi, Urooj; Taha, Muhammad; Ul-Haq, Zaheer (Elsevier, 2022)A library of hydrazinyl thiazole-linked indenoquinoxaline hybrids 1-36 were synthesized via a multistep reaction scheme. All synthesized compounds were characterized by various spectroscopic techniques including EI-MS ... -
Indenoquinoxaline-phenylacrylohydrazide hybrids as promising drug candidates for the treatment of type 2 diabetes: In vitro and in silico evaluation of enzyme inhibition and antioxidant activity
Hameed, Shehryar; Saleem, Faiza; Özil, Musa; Baltaş, Nimet; Salar, Uzma; Ashraf, Sajda; Ul-Haq, Zaheer; Taha, Muhammad; Khan, Khalid Mohammed (Elsevier, 2024)Existing drugs that are being used to treat type-2 diabetes mellitus are associated with several side effects; thus, exploring potential drug candidates is still an utter need these days. Hybrids of indenoquinoxaline and ... -
Indole-pyridine carbonitriles: multicomponent reaction synthesis and bio-evaluation as potential hits against diabetes mellitus
Solangi, Mehwish; Khan, Khalid Mohammed; Ji, Xingyue; Özil, Musa; Baltaş, Nimet; Salar, Uzma; Khan, Alamgir; Ul-Haq, Zaheer; Meghwar, Herchand; Taha, Muhammad (2023)Background: Diabetes mellitus is a significant health disorder; therefore, researchers should focus on discovering new drug candidates. Methods: A series of indole-pyridine carbonitrile derivatives, 1-34, was synthesized ... -
Microwave-assisted synthesis of some novel benzimidazole derivatives containing imine function and evaluation of their antimicrobial activity
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay (Wiley, 2014)4-Bromo-o-phenylenediamine and ethylimido-p-bromophenylacetate, 1, were subjected to microwave irradiation to synthesize benzimidazole derivative, compound 2. Ester derivative, 3, and hydrazide derivative, 4, of compound ... -
Microwave-promoted synthesis and biological activity of some 2-hetarylmethyl-4-(4-hetarylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one derivatives
Özil, Musa; Bodur, Osman; Ülker, Serdar; Kahveci, Bahittin (Springer, 2015)A series of fused and non-fused 1,2,4-triazole derivatives were prepared starting from ethyl 4-[1-(2-ethoxy-2-oxoethyl)-3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]benzoate. Firstly, both ethyl ester groups were ... -
Molecular docking studies and synthesis of novel bisbenzimidazole derivatives as inhibitors of alpha-glucosidase
Özil, Musa; Emirik, Mustafa; Beldüz, Ali; Ülker, Serdar (Pergamon-Elsevier Science Ltd, 2016)A series of bisbenzimidazole derivatives starting from o-phenylenediamine and 4-nitro-o-phenylenediamine were prepared with oxalic acid. Most of the reactions were conducted using both the microwave and conventional methods ... -
Multicomponent diastereoselective synthesis of tetrahydropyridines as α-amylase and α-glucosidase enzymes inhibitors
Saleem, Faiza; Shamim, Fariha; Özil, Musa; Baltaş, Nimet; Salar, Uzma; Ashraf, Sajda; Ul-Haq, Zaheer; Taha, Muhammad; Solangi, Mehwish; Khan, Khalid Mohammed (2023)Background: Researchers seeking new drug candidates to treat diabetes mellitus have been exploring bioactive molecules found in nature, particularly tetrahydropyridines (THPs). Methods: A library of THPs (1–31) were ... -
Recent advances on smart glycoconjugate vaccines in infections and cancer
Anderluh, Marko; Berti, Francesco; Bzducha-Wrobel, Anna; Chiodo, Fabrizio; Colombo, Cinzia; Compostella, Federica; Durlik, Katarzyna; Ferhati, Xhenti; Holmdahl, Rikard; Jovanovic, Dragana; Kaca, Wieslaw; Lay, Luigi; Marinovic-Cincovic, Milena; Marradi, Marco; Özil, Musa; Polito, Laura; Reina, Jose Juan; Reis, Celso A.; Sackstein, Robert; Silipo, Alba; Svajger, Urban; Vanek, Ondrej; Yamamoto, Fumiichiro; Richichi, Barbara; van Vliet, Sandra J. (Wiley, 2021)Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, ... -
Regioselective syntheses of 2-oxopyridine carbonitrile derivatives and evaluation for antihyperglycemic and antioxidant potential
Saleem, Faiza; Haider, Maham; Khan, Khalid Mohammed; Özil, Musa; Baltaş, Nimet; Ul-Haq, Zaheer; Qureshi, Urooj; Salar, Uzma; Taha, Muhammad; Hameed, Shehryar; Ullah, Nisar (Elsevier, 2023)A library of 2-oxopyridine carbonitriles 1-34 was synthesized by regioselective nucleophilic substitution reactions. In the first step, a one-pot multicomponent reaction yield pyridone intermediates. The resulting pyridone ... -
A simple and efficient synthesis of benzimidazoles containing piperazine or morpholine skeleton at C-6 position as glucosidase inhibitors with antioxidant activity
Özil, Musa; Parlak, Cansu; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2018)A novel 2-(aryl)-6-morpholin-4-yl(or 4-methylpiperazin-1-yl)-1H-benzimidazole derivatives were designed and expeditiously synthesized starting from 5-morpholin-4-yl(or 4-methylpiperazin-1-yl)-2-nitroaniline with various ... -
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
Özil, Musa; Emirik, Mustafa; Etlik, Semiha Yılmaz; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2016)A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ... -
Solvent-free synthesis of novel phthalocyanines containing triazole derivatives under microwave irradiation
Özil, Musa; Canpolat, Mutlu (Pergamon-Elsevier Science Ltd, 2013)An efficient microwave processing method has been developed for the synthesis of novel metal-free phthalocyanine and metallophthalocyanines containing 1,2,4-triazole-3-one derivatives under microwave irradiation in ... -
Synthesis and characterization of two new hydroxamic acids derivatives and their metal complexes. An investigation on the keto/enol, E/Z and hydroxamate/hydroxirnate forms
Adıgüzel, Ekrem; Yılmaz, Fatih; Emirik, Mustafa; Özil, Musa (Elsevier Science Bv, 2017)2-phenylbenzimidazole-N-acetohydroxamic acid (HL1), 2-phenylbenzimidazole-N-butanohydroxamic acid (HL2) and Ni(II), Cu(II), Zn(II) and Cd(II) metal complexes have been synthesized and characterized by elemental analyses, ...