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The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia

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Erişim

info:eu-repo/semantics/closedAccess

Tarih

2023

Yazar

Kazancıoğlu, Leyla
Batçık, Şule
Arpa, Medeni
Kazdal, Hızır
Koyuncu, Tolga
Bilgin, H.
Erel, Özcan

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Künye

Kazancioglu, L., Batcik, S., Arpa, M., Kazdal, H., Koyuncu, T., Bilgin, H., & Erel, O. (2023). The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia. European review for medical and pharmacological sciences, 27(18), 8523–8530. https://doi.org/10.26355/eurrev_202309_33777

Özet

Abstract. – OBJECTIVE: We aimed to investigate the relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients scheduled for elective transurethral prostate resection surgery with spinal anesthesia. PATIENTS AND METHODS: 71 patients classified as categories 1 and 2, according to American Society of Anesthesiologists (ASA) classification, were included in the study. The core temperature of the patients was recorded in the operating room after monitoring, at 5 and 30 minutes after spinal anesthesia. Total thiols, native thiols, disulfide amounts, disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol were calculated as percentages after monitorization (Tpreoperative) and at 60 minutes after spinal anesthesia (Tintraoperative). RESULTS: The disulfide levels in the Tintraoperative period (29±8.9 mmol/L) were higher than the disulfide levels measured in the Tpreoperative period (18.2±8.8 mmol/L) (p<0.001). In the Tpreoperative period, the disulfide/native thiol (%) level was 4.6±2, while the disulfide/total thiol (%) level was 4.2±1.6. In the Tintraoperative period, the disulfide/native thiol (%) level was 8±2.3, while the disulfide/total thiol (%) level was 6.8±1.7. Native thiol/total thiol (%) levels for the Tpreoperative and Tintraoperative periods were 91.5±3.3 mmol/L and 86.3±3.4 mmol/L, respectively. A correlation was found between native, total thiol levels and patient age in the Tpreoperative and Tintraoperative periods. CONCLUSIONS: Oxidative stress can be reduced in geriatric patients with the possibility of developing involuntary perioperative hypothermia by regularly monitoring body temperature and applying warming techniques.

Kaynak

European Review for Medical and Pharmacological Sciences

Cilt

27

Sayı

18

Bağlantı

https://doi.org/10.26355/eurrev_202309_33777
https://hdl.handle.net/11436/8584

Koleksiyonlar

  • PubMed İndeksli Yayınlar Koleksiyonu [2443]
  • TF, Dahili Tıp Bilimleri Bölümü Koleksiyonu [1559]
  • TF, Temel Tıp Bilimleri Bölümü Koleksiyonu [691]
  • WoS İndeksli Yayınlar Koleksiyonu [5260]



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