dc.contributor.author | Kazancıoğlu, Leyla | |
dc.contributor.author | Batçık, Şule | |
dc.contributor.author | Arpa, Medeni | |
dc.contributor.author | Kazdal, Hızır | |
dc.contributor.author | Koyuncu, Tolga | |
dc.contributor.author | Bilgin, H. | |
dc.contributor.author | Erel, Özcan | |
dc.date.accessioned | 2023-10-27T06:49:43Z | |
dc.date.available | 2023-10-27T06:49:43Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Kazancioglu, L., Batcik, S., Arpa, M., Kazdal, H., Koyuncu, T., Bilgin, H., & Erel, O. (2023). The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia. European review for medical and pharmacological sciences, 27(18), 8523–8530. https://doi.org/10.26355/eurrev_202309_33777 | en_US |
dc.identifier.issn | 1128-3602 | |
dc.identifier.issn | 2284-0729 | |
dc.identifier.issn | 1128-3602 | |
dc.identifier.uri | https://doi.org/10.26355/eurrev_202309_33777 | |
dc.identifier.uri | https://hdl.handle.net/11436/8584 | |
dc.description.abstract | Abstract. – OBJECTIVE: We aimed to investigate the relationship between intraoperative
body temperature and thiol/disulfide balance in
geriatric patients scheduled for elective transurethral prostate resection surgery with spinal
anesthesia.
PATIENTS AND METHODS: 71 patients classified as categories 1 and 2, according to American Society of Anesthesiologists (ASA) classification, were included in the study. The core temperature of the patients was recorded in the operating room after monitoring, at 5 and 30 minutes after spinal anesthesia. Total thiols, native
thiols, disulfide amounts, disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol were calculated as percentages after monitorization (Tpreoperative) and at 60 minutes after spinal
anesthesia (Tintraoperative).
RESULTS: The disulfide levels in the Tintraoperative
period (29±8.9 mmol/L) were higher than the disulfide levels measured in the Tpreoperative period (18.2±8.8
mmol/L) (p<0.001). In the Tpreoperative period, the disulfide/native thiol (%) level was 4.6±2, while the disulfide/total thiol (%) level was 4.2±1.6. In the Tintraoperative
period, the disulfide/native thiol (%) level was 8±2.3,
while the disulfide/total thiol (%) level was 6.8±1.7.
Native thiol/total thiol (%) levels for the Tpreoperative
and Tintraoperative periods were 91.5±3.3 mmol/L and
86.3±3.4 mmol/L, respectively. A correlation was
found between native, total thiol levels and patient
age in the Tpreoperative and Tintraoperative periods.
CONCLUSIONS: Oxidative stress can be reduced in geriatric patients with the possibility of
developing involuntary perioperative hypothermia by regularly monitoring body temperature
and applying warming techniques. | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Thiols | en_US |
dc.subject | Disulfides | en_US |
dc.subject | Transurethral prostate resection | en_US |
dc.subject | Hypothermia, | en_US |
dc.subject | Oxidative stress | en_US |
dc.title | The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Kazancıoğlu, Leyla | |
dc.contributor.institutionauthor | Batçık, Şule | |
dc.contributor.institutionauthor | Arpa, Medeni | |
dc.contributor.institutionauthor | Kazdal, Hızır | |
dc.contributor.institutionauthor | Koyuncu, Tolga | |
dc.identifier.doi | 10.26355/eurrev_202309_33777 | en_US |
dc.identifier.volume | 27 | en_US |
dc.identifier.issue | 18 | en_US |
dc.identifier.startpage | 8523 | en_US |
dc.identifier.endpage | 8530 | en_US |
dc.relation.journal | European Review for Medical and Pharmacological Sciences | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |