Kurum Yazarı "Yazıcı, Zihni Açar" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus
Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Şahin, Zafer; Akyıldız, Kerimali; Karataş, Kader Semra; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar (Elsevier, 2023)Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side ef-fects, including cognitive impairment. Agomelatine, a synthetic melatonin analogue, is an important antide-pressant. ... -
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Akyıldız, Kerimali; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar; Yılmaz, Adnan (Elsevier, 2021)It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ... -
Contribution of neutrophil activation in the differentiation of urine infection and contamination in pregnant women
Şahin, Kazım; Dilek, Aziz Ramazan; Güven, Emine Seda Güvendağ; Yazıcı, Zihni Açar (Karger, 2015)Background: Urinary tract infections are among the most common bacterial infections of humans. Urine culture is the gold standard for asymptomatic bacteriuria and pyuria is not always present in bacteriuria, nor is it ... -
Correlation of suicidal thoughts and toxoplasmosis in patients with depression
Bahçeci, İlkay; Bahçeci, Bülent; Şentürk, Şenol; Yıldız, İlknur Esen; Yazıcı, Zİhni Açar (Cureus Inc., 2021)Objective We investigated the correlation between serum anti-Toxplasma gondii IgG and suicidal thoughts in depressive patients. Methods Depressive patients with (n = 100) and without (n = 100) suicidal thoughts ... -
COVID-19 vaccine immunity in oncology patients
Uslu, Gonca Hanedan; Rakıcı, Sema Yılmaz; Çiçek, Ayşegül Çopur; Yazıcı, Zihni Açar (AEPRESS Sro, 2023)BACKGROUND: To investigate the effect of vaccine types applied in our country against 2019 coronavirus disease on the formation of protective antibodies in oncology patients. MATERIALS AND METHODS: The data of 81 cancer ... -
Effect of the prenatal electromagnetic field exposure on cochlear nucleus neurons and oligodendrocytes in rats
Tümkaya, Levent; Baş, Orhan; Mercantepe, Tolga; Çınar, Seda; Özgür, Abdulkadir; Yazıcı, Zihni Açar (Springer Heidelberg, 2022)Electromagnetic radiation from elecromagnetic field (EMF) sources has been an important health concern for a long time. The vast majority of this exposure is due to the widespread use of mobile phones, an important source ... -
Effects of gadodiamide and gadoteric acid on lung tissue: A comparative study
Çeliker, Fatma Beyazal; Tümkaya, Levent; Suzan, Zehra T.; Topçu, Atilla; Mercantepe, Tolga; Çınar, Seda; Yazıcı, Zihni Açar; Yılmaz, Adnan (Wiley, 2022)We set out to investigate the effects of gadodiamide and gadoteric acid, used for magnetic resonance imaging, on the lungs. In this study, 32 male Sprague Dawley rats were used. These were allocated into four groups; The ... -
Glass particle contamination threat in nursing practice: A pilot study
Erkoç Hut, Arzu; Yazıcı, Zihni Açar (Wiley, 2021)Aim The aim of this study was to determine the level of glass particle contamination from medical ampoules during breakage in nursing practice and their removal by filtration. Design Glass medical ampoules were broken-open ... -
Identification of the potential matrix protein of invertebrate iridescent virus 6 (IIV6)
Gencer, Dönüş; Yeşilyurt, Aydın; Özşahin, Emine; Muratoğlu, Hacer; Yazıcı, Zihni Açar; Demirbağ, Zihni; Nalcacıoğlu, Remziye (Elsevier, 2023)Invertebrate iridescent virus 6 (IIV6) is a nucleocytoplasmic virus with a similar to 212 kb linear dsDNA genome that encodes 215 putative open reading frames (ORFs). Proteomic analysis has revealed that the IIV6 virion ... -
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab
Bahçeci, İlkay; Tümkaya, Levent; Mercantepe, Tolga; Aslan, Nuray; Duran, Ömer Faruk; Söztanacı, Umut Serkan; Yazıcı, Zihni Açar (Taylor & Francis Ltd., 2022)Methotrexate (MTX) has been in use for the treatment of rheumatoid arthritis (RA), psoriasis, and cancer since 1948. Its toxic side effects on tissues and organs have been well documented but splenotoxicity has not been ... -
Lasting hepatotoxic effects of prenatal mobile phone exposure
Yılmaz, Adnan; Tümkaya, Levent; Akyıldız, Kerimali; Kalkan, Yıldıray; Bodur, Ali Fuat; Sargın, Fatma; Efe, Hasan; Uydu, Hüseyin Avni; Yazıcı, Zihni Açar (Taylor & Francis Ltd, 2017)Objective: in this study, the livers of rats born to mothers exposed to electromagnetic field (EMF) were examined 60 days postpartum for biochemical and histopathological changes.Methods: Pregnant rats were exposed to ... -
Lymphocyte subpopulations in Sheehan's syndrome
Atmaca, Hulusi; Araslı, Mehmet; Yazıcı, Zihni Açar; Armutçu, Ferah; Tekin, İshak Özel (Springer, 2013)The role of autoimmunity in the development of Sheehan's syndrome is obscure. There are a limited number of studies investigating the immunological alterations accompanying Sheehan's Syndrome. Our objective was to evaluate ... -
Marine-Lenhart syndrome with papillary thyroid carcinoma
Atmaca, Hulusi; Çolak, Ramis; Yazıcı, Zihni Açar; Kefeli, Mehmet; Tosun, Fevziye Canbaz (Medknow Publications & Media Pvt Ltd, 2015)Graves' disease with accompanying functioning nodules is known as Marine-Lenhart syndrome. Autonomously functioning thyroid nodules (AFTNs) also within Graves' thyroid tissue are almost always bening in nature. A 45-year-old ... -
Protective effects of amifostine, curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damage in rats
Mercantepe, Tolga; Ünal, Deniz; Tümkaya, Levent; Yazıcı, Zihni Açar (Spandidos Publ Ltd, 2018)Cisplatin is an effective antineoplastic drug that is usually used to treat a number of different types of cancer in the clinic. One of the most notable side effects of cisplatin use is infertility. the present study was ... -
Radioprotective effects of dexmedetomidine on X-ray-induced testicular damage
Dil, Eyüp; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Yılmaz, Adnan; Samancı, Tuğba Çelik; Yazıcı, Zihni Açar (Verduci Publisher, 2023)OBJECTIVE: Approximately 70% of cancer patients require radiotherapy. However, despite its effectiveness in the treatment of cancer, radiotherapy can also affect and damage surrounding healthy tissues in addition to ... -
The use of cerebral oximetry in acute carbon monoxide intoxication: A preliminary study
Kalkan, Asım; Bilir, Özlem; Ersunan, Gökhan; Yazıcı, Zihni Açar; Özel, Deniz; Taş, Mahmut; Yavaşi, Özcan (Keio University School of Medicine, 2015)The purpose of this study was to assess the clinical usefulness of near-infrared spectroscopy (cerebral oximetry) in patients presenting to the emergency department (ED) with carbon monoxide (CO) intoxication. Eighteen ... -
Wernicke's encephalopathy in a patient with unresectable gastric carcinoma and literature review
Rakıcı, Sema Yılmaz; Erdemli, Sema Doğan; Yazıcı, Zihni Açar; Cengiz, Ercüment; Acar, Özlem Günay; Tufan, Gülnihal (E-Century Publishing Corp, 2015)Wernicke's encephalopathy (WE) is a disease classically associated with nutrition deficiency. It is characterized by typical symptoms like confusion, ataxia and ophthalmoparesis, and developes due to thiamine deficieny in ...