Kurum Yazarı "Mercantepe, Tolga" DŞHF, Klinik Bilimler Bölümü Koleksiyonu İçin Listeleme
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Celastrol restricts experimental periodontitis related alveolar bone loss by suppressing inflammatory cytokine response
Altın, Ahmet; Korkmaz, Meltem Zihni; Atak, Mehtap; Mercantepe, Tolga; Yılmaz, Hülya Kılıç (China Medical University, 2023)Introduction: Periodontitis is a common chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. The host defense mechanisms are responsible for inflamatuar and destructive ... -
Dexamethasone and concentrated growth factors on peripheral nerve injury: A clinic-relevant animal study
Kalyoncu, Alperen; Balaban, Emre; Mercantepe, Tolga; Tümkaya, Levent (Elsevier, 2024)Background: Mandibular nerve injury is a common clinical condition that affects clinicians’ management and patients’ quality of life. In the literature, there are various effective treatments available. The primary purpose ... -
Effects of mineral trioxide aggregate and methyl sulfonyl methane on pulp exposure via RUNX2 and RANKL pathways
Ateş, Altar; Kurt, Ayça; Mercantepe, Tolga (Springer Link, 2024)The aim of this study was to determine the therapeutic effects of mineral trioxide aggregate (MTA) and methyl sulfonyl methane (MSM) on pulp damage due to pulp exposure through the RUNX2 and RANKL pathways. Seventy-two ... -
Influences of periodontitis on hippocampal inflammation, oxidative stress, and apoptosis in rats
Köse, Oğuz; Altın, Ahmet; Bayrakdar, Sevda Kurt; Bostan, Semih Alperen; Mercantepe, Tolga; Akyıldız, Kerimali; Tümkaya, Levent; Yılmaz, Adnan; Köse, Sefanur; Yemenoğlu, Hatice; Şener, Leyla Türker; Göker, Kuluslu (Wiley, 2021)Background and aim The hippocampus, which has a central role in cognitive and behavioral activities, is one of the most sensitive parts of the brain to systemic inflammatory diseases. This animal study aims to comprehensively ... -
Melatonin ameliorates periodontitis related inflammatory stress at cardiac left ventricular tissues in rats
Köse, Oğuz; Bayraktar, Sevda Kurt; Akyıldız, Kerimali; Altın, Ahmet; Arabacı, Taner; Yemenoğlu, Hatice; Korkmaz, Mehmet Zihni; Köse, Taha Emre; Şener, Leyla Türker; Mercantepe, Tolga; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2020)BackgroundThe aim of this experimental rat study was to investigate the potential inflammatory effects of periodontitis on cardiac left ventricular tissue and the therapeutic activity of melatonin on these effects. ... -
Melatonin improves periodontitis-induced kidney damages by decreasing inflammatory stress and apoptosis in rats
Köse, Oğuz; Bayrakdar, Sevda Kurt; Ünver, Büşra; Altın, Ahmet; Akyıldız, Kerimali; Mercantepe, Tolga; Bostan, Semih Alperen; Arabacı, Taner; Türker Şener, Leyla; Köse, Taha Emre; Tümkaya, Levent; Yılmaz, Adnan; Kuluşlu, Göker (Wiley-Blackwell, 2020)Background: Two main aims of this animal study were to inspect the possible effects of periodontitis on the structure and functions of the kidneys and the therapeutic effectiveness of melatonin. Methods: Twenty-four male ... -
Periodontitis exacerbates the renal degenerative effects of obesity in rats
Kurt-Bayrakdar, Sevda; Köse, Oğuz; Altın, Ahmet; Akyıldız, Kerimali; Mercantepe, Tolga; Bostan, Semih Alperen; Köse, Taha Emre; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2021)Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ... -
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis
Bostan, Semih Alperen; Yemenoğlu, Hatice; Köse, Oğuz; Akyıldız, Kerimali; Mercantepe, Tolga; Saral, Sinan; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2024)Objective and Background: Psychological stress is a potential modifiable environmental risk factor causally related to the exacerbation of periodontitis and other chronic inflammatory diseases. This animal study aimed to ...