Ara
Toplam kayıt 296, listelenen: 101-110
Evaluation of monomer elution, microhardness, and roughness of experimental dental composite resins prepared from Bis-EFMA, a novel monomer system
(Wiley, 2021)
This study aimed to compare the monomer elution, microhardness, and roughness of experimental resin-based composites (RBCs) prepared from a novel monomer system derived from 9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene) ...
Design and synthesis of benzimidazole derivatives as apoptosis-inducing agents by targeting Bcl-2 protein
(Springer, 2022)
Bcl-2, an anti-apoptotic protein, is a well-known and appealing cancer therapy target. Novel series of benzimidazole derivatives were synthesized and tested for their activity as Bcl-2 inhibitors on T98G glioblastoma, PC3 ...
Synthesis, structural, spectral, antioxidant, bioactivity and molecular docking investigations of a novel triazole derivative
(Taylor & Francis Ltd., 2021)
The structural, spectroscopic and electronic properties of 4-(4-nitrophenyl)-5-(pyridin-3-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione have been analyzed by using single crystal X-ray diffraction (SCXRD), H-1 and C-13 NMR ...
Some characteristics of new and innovative COX inhibitor derivatives: Potent hCA-I and hCA-II inhibitors supported by molecular docking studies
(John & Wiley Ltd., 2022)
In this study, two novel metallophthalocyanines (ZnPc and CoPc) were synthesized using the corresponding metal salts 4-(4-(4-[4-chlorophenyl]-5-methylisoxazol-3-yl)phenoxy)-phthalonitrile (11), prepared from the reaction ...
Urease and acetylcholinesterase enzyme inhibitor novel phthalonitrile azo compounds
(Scientific Publishers, 2022)
Based on the relationship between Helicobacter pylori and Alzehimer's disease, new azo phthalonitrile compounds containing different amino pyridines have been synthesized. These compounds can inhibit both Urease and ...
Synthesis and docking studies of novel benzimidazole derivatives containing thiophene and triazole rings as potential urease inhibitors
(Springer, 2022)
Abstract: A new series of 5,6-dichloro-benzimidazoles containing thiophene ring derivatives of thiosemicarbazides and triazoles were designed, synthesized and characterized by spectral methods like as IR, 1H-NMR, 13C-NMR ...
Investigation of the usability of some triazole derivative compounds as drug active ingredients by ADME and molecular docking properties
(University Mohammed Premier Oujda, 2022)
In this study, some important ADME parameters such as physicochemical properties, lipophilicity, water solubility, pharmacokinetics, medicinal chemistry and drug-likeness properties of ten triazole derivative compounds, ...
Potential therapeutic effect of turmeric contents against SARS-CoV-2 compared with experimental COVID-19 therapies: in silico study
(Taylor & Francis Inc, 2020)
Inspired by the 'There is no scientific evidence that turmeric prevents COVID-19' statement made by WHO, the protective or therapeutic potential of the compounds in turmeric contents was investigated against COVID-19 with ...
Synthesis of Some New Ciprofloxacin Hybrids as Potential Antimicrobial Agents
(Wiley, 2017)
A new series of ciprofloxacin hybrid compounds as new type of antimicrobial agents were synthesized and evaluated for antibacterial activity against Gram-positive and Gram-negative bacteria.
Crystallographic, spectroscopic (FTIR and NMR) and quantum computational calculation studies on bis(2-methoxy-4-((E)-prop-1-enyl)phenyl)oxalate
(Elsevier Science Bv, 2017)
In this paper, we report first, a new synthesis of bis(2-methoxy-4-((E)-prop-1-enyl)phenyl)oxalate, namely, C22H22O6, (I). Then, we present detailed FTIR, H-1 NMR,C-13 NMR spectroscopies and single-crystal X-ray diffraction ...