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Toplam kayıt 7, listelenen: 1-7
Molecular docking studies and synthesis of novel bisbenzimidazole derivatives as inhibitors of alpha-glucosidase
(Pergamon-Elsevier Science Ltd, 2016)
A series of bisbenzimidazole derivatives starting from o-phenylenediamine and 4-nitro-o-phenylenediamine were prepared with oxalic acid. Most of the reactions were conducted using both the microwave and conventional methods ...
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
(Academic Press Inc Elsevier Science, 2016)
A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ...
Synthesis and molecular docking studies of potent urease inhibitors based on benzoxazole scaffold
(Wiley-V C Verlag GMBH, 2021)
In this study, we report the synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzoxazole derivatives. The title compound in the series namely (2-(benzo[d]oxazol-2-ylthi ...
Developing a scaffold for urease inhibition based on benzothiazoles: Synthesis, docking analysis, and therapeutic potential
(Wiley-V C Verlag GMBH, 2021)
The synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzothiazole derivatives are reported. The title compounds in the two series, namely, 2-({5-[(benzothiazol-2-ylthio ...
Synthesis and characterization of two new hydroxamic acids derivatives and their metal complexes. An investigation on the keto/enol, E/Z and hydroxamate/hydroxirnate forms
(Elsevier Science Bv, 2017)
2-phenylbenzimidazole-N-acetohydroxamic acid (HL1), 2-phenylbenzimidazole-N-butanohydroxamic acid (HL2) and Ni(II), Cu(II), Zn(II) and Cd(II) metal complexes have been synthesized and characterized by elemental analyses, ...
Synthesis and molecular docking studies of novel triazole derivatives as antioxidant agents
(Bentham Science Publ Ltd, 2020)
A series of 1,2,4-triazole and 1,2,4- thiadiazole derivatives were prepared starting from ethyl 4-(3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)benzoate. Firstly, both ethyl ester groups were simultaneously transformed ...
Binuclear Cu(II), Ni(II) and Zn(II) complexes of hydrazone Schiff bases: Synthesis, spectroscopy, DFT calculations, and SOD mimetic activity
(Elsevier, 2023)
Two new salicylaldimine-based N-heterocyclic hydrazone ligands, N'-[(2-hydroxyphenyl) methylene]2-(2-phenyl-1H-benzimidazol-1-yl)acetohydrazone (H 2 L 1 ) and 2-[2-(3-chlorobenzyl)-1H-benzimidazol-1yl]-N'-[(2-(hydroxyimi ...