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Toplam kayıt 26, listelenen: 21-26
A simple and efficient synthesis of benzimidazoles containing piperazine or morpholine skeleton at C-6 position as glucosidase inhibitors with antioxidant activity
(Academic Press Inc Elsevier Science, 2018)
A novel 2-(aryl)-6-morpholin-4-yl(or 4-methylpiperazin-1-yl)-1H-benzimidazole derivatives were designed and expeditiously synthesized starting from 5-morpholin-4-yl(or 4-methylpiperazin-1-yl)-2-nitroaniline with various ...
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
(Academic Press Inc Elsevier Science, 2018)
In this study, a new series of benzimidazole and bisbenzimidazole derivatives were prepared via the reaction of iminoester hydrochlorides and o-phenylenediamines and then screened for their lipase inhibition properties. ...
Synthesis, inhibitory properties on the metabolic enzymes and antioxidant activity of a new series benzimidazole derivatives
(Editura Acad Romane, 2019)
In this study, a series of new 1, 2-disubstituted benzimidazole was synthesized starting from 5, 6-dichloro-2-(4-methoxybenzyl)-1H-benzimidazole compound which was converted to the ester and hydrazide derivative, respectively. ...
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
(Academic Press Inc Elsevier Science, 2019)
A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ...
Synthesis, antioxidant and antiurease activities of some new 5,6-dichloro-2-(4-fluorobenzyl)-1H-benzimidazolle derivatives containing furan, oxadiazole, triazole and thiadiazole moieties
(Bentham Science Publ Ltd, 2019)
Background: Benzimidazoles and its derivatives have been attracting interest for many years because of their biological activities. Benzimidazoles containing different heterocyclic moieties have wide range of biological ...
Synthesis and characterization of ring-type and branched polymers including polyethylene glycols by "click" chemistry
(Springer International Publishing Ag, 2019)
Synthesis of ring-type (or branched) polymers including polyethylene glycols was archived via "click" chemistry of 5,6-diazido-2-benzyl-1H-benzimidazole (Di-N-3) [or triazidoacetohydrazide derivative (Tri-N-3)] and terminally ...