TF, Dahili Tıp Bilimleri Bölümü Koleksiyonu by Institution Author "Arpa, Medeni"
Now showing items 1-19 of 19
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Assessment of thiol/disulphide homeostasis in patients with knee osteoarthritis
Devrimsel, Gül; Arpa, Medeni; Beyazal, Münevver Serdaroğlu; Erel, Özcan (CSIR-National Institute of Science Communication and Policy Research (CSIR-NIScPR), 2021)Our aim was to explore the thiol/disulphide homeostasis and the link with functional status in patients who have knee OA. Sixty knee OA patients and 50 healthy individuals were enrolled in this study. We measured serum ... -
Association of serum interleukin-17 and Interleukin-23 levels with disease activity, function, mobility, enthesitis index in patients with ankylosing spondylitis
Beyazal, Münevver Serdaroğlu; Tayfun, Aliekber; Devrimsel, Gül; Yıldırım, Murat; Arpa, Medeni (Georg Thieme Verlag, 2022)Aim: More and more studies have demonstrated that the interleukin (IL)-23/IL-17 axis is highly associated with immune dysfunction and activated autoimmune inflammation. The purposes of this study were to determine the serum ... -
A comparison study of dual-energy spectral CT and 18F-FDG PET/CT in primary tumors and lymph nodes of lung cancer
Kupik, Osman; Metin, Yavuz; Eren, Gülnihan; Metin, Nurgül Orhan; Arpa, Medeni (Turkish Society of Radiology, 2021)PURPOSE We aimed to investigate whether there is a correlation between dual-energy spectral computed tomography (DESCT) and 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) parameters ... -
Do volume-based and metabolic 18F FDG PET/CT parameters identify groups at risk for poor prognosis in patients with newly diagnosed metastatic and non-metastatic non-small cell lung cancer?
Kupik, Osman; Bozkurt, Mehmet; Asa, Sertaç; Eren, Gülnihan; Gündoğdu, Hasan; Arpa, Medeni (Akad Doktorlar Yayinevi, 2020)To determine the relationship between F-18 FDG PET/CT parameters of the primary tumor/nodal metastasis/distant metastasis and overall survival (OS) of patients with newly diagnosed non-small cell lung cancer (NSCLC). Data ... -
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
Topçu, Atilla; Öztürk, Aykut; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Taylor & Francis Ltd., 2022)Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ... -
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
Özdemir, Ayşe; Topçu, Atilla; Mercantepe, Tolga; Arpa, Medeni; Karakaş, Sibel Mataracı; Özdemir, Ali Sezin; Tümkaya, Levent; Mercantepe, Filiz (Verduci Publisher, 2023)OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
Deniz, Esra; Topçu, Atilla; Öztürk, Aykut; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
Evaluation of thiol-disulfide homeostasis in active ankylosing spondylitis patients
Arpa, Medeni; Şen, Bayram; Beyazal, Münevver Serdaroğlu; Erel, Özcan (Ediciones Doyma, S.L., 2021)Introduction and objectives: The etiopathogenesis of ankylosing spondylitis (AS), which is a chronic, progressive, inflammatory, systemic disease, has not been fully elucidated yet. Thiol-disulfide homeostasis, a component ... -
Evaluation of thiol/disulfide homeostasis in bronchiectasis
Özyurt, Songül; Özçelik, Neslihan; Kara, Bilge Yılmaz; Arpa, Medeni; Metin, Yavuz; Erel, Özcan; Neşelioğlu, Salim (Hindawi, 2022)Purpose. Thiols are sulfhydryl-containing organic compounds that have an important role in preventing cellular oxidative stress. This study compares the blood oxidative stress marker levels in bronchiectasis cases during ... -
Neutrophil gelatinase-associated lipocalin as a potential biomarker for pulmonary thromboembolism
Özyurt, Songül; Karataş, Mevlüt; Arpa, Medeni; Kara, Bilge Yılmaz; Duman, Hakan; Memoğlu, Melek; Şahin, Ünal (Walter de Gruyter Gmbh, 2020)Objective: Pulmonary thromboembolism (PTE) is a clinical condition that can be lethal unless promptly diagnosed and treated. the objective was to evaluate the significance of scrum neutrophil gelatinase-associated lipocalin ... -
PET-CT and MR imaging in the management of axillary nodes in early stage breast cancer
Baran, Mehmet Tarık; Gündoğdu, Hasan; Demiral, Gökhan; Kupik, Osman; Arpa, Medeni; Pergel, Ahmet (Coll Physicians & Surgeons Pakistan, 2020)Objective: To discriminate between malignant or benign axillary lymph nodes in breast cancer using MRI, PET-CT, and sentinel lymph node biopsy. Study Design: Observational study. Place and Duration of Study: Department of ... -
Prognostic significance of C-reactive protein/albumin and neutrophil/lymphocyte ratios in patients with COVID-19
Polat, Hatice Beyazal; Arpa, Medeni; Polat, Zehra; Beyazal, Mehmet; Çeliker, Fatma Beyazal; Ayaz, Teslime; Ertürk, Ayşe (Publishing Office of the University of Rzeszow, 2024)Introduction and aim. COVID-19 causes an uncontrolled and generalized inflammatory response of the host immune system. Early recognition of the disease and early prediction of the clinical course are of great importance. ... -
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway
Öztürk, Aykut; Topçu, Atilla; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Yılmaz, Eda Kutlu (Wiley, 2022)Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ... -
The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis
Yıldız, İlknur Esen; Topçu, Atilla; Bahçeci, İlkay; Arpa, Medeni; Tümkaya, Levent; Mercantepe, Tolga; Batçık, Şule; Yıldız, Yasin (Pergamon-Elsevier Science Ltd., 2021)Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ... -
Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats
Rakıcı, Sema Yılmaz; Tümkaya, Levent; Erdivanlı, Özlem Çelebi; Yazıcı, Ufuk; Dursun, Engin; Arpa, Medeni; Mercantepe, Tolga (Taylor & Francis Ltd, 2019)Purpose: We investigated the radioprotective effect of endogenous melatonin release at different times associated with the circadian rhythm on head and neck radiotherapy. Materials and methods: Two groups of animals were ... -
Relationship between galectin-3 level and disease activity in ankylosing spondylitis patients
Devrimsel, Gül; Arpa, Medeni; Beyazal, Münevver Serdaroğlu (Springer, 2023)Background and aimsAnkylosing spondylitis (AS) is a chronic inflammatory disease that chiefly affects the sacroiliac joints and the spine. Galectin-3, a chimera-type member of the galectin family, binds glycoconjugates ... -
The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia
Kazancıoğlu, Leyla; Batçık, Şule; Arpa, Medeni; Kazdal, Hızır; Koyuncu, Tolga; Bilgin, H.; Erel, Özcan (2023)Abstract. – OBJECTIVE: We aimed to investigate the relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients scheduled for elective transurethral prostate resection surgery ... -
The relationship of serum asymmetric dimethylarginine concentrations and lung involvement in patients with COVID-19 infection
Emlek, Nadir; Yılmaz, Ahmet Seyda; Ergül, Elif; Gündoğdu, Hasan; Arpa, Medeni; Koç, Haldun; Öztürk, Muhammet; Aydın, Cihan (2021)Aim: COVID-19 infections the tissue through angiotensin converting enzyme 2 receptor, which is also expressed on endothelial cells. Endothelial dysfunction may be associated with lung involvement. Asymmetric dimethylarginine ...