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Toplam kayıt 67, listelenen: 31-40
Comparison of linear versus macrocyclic gadolinium chelates in rat skeletal muscle
(2022)
OBJECTIVE: We investigated the effects on skeletal muscle of gadolinium based linear and macrocyclic radiocontrast agents
applied at experimental intervals using histopathological methods.
METHODS: Thirty-two male ...
The protective effects of red ginseng and amifostine against renal damage caused by ionizing radiation
(2022)
This study aimed to elucidate the effects of amifostine (ethyol) (AM), a synthetic radioprotector, and red ginseng (RG), a natural radioprotective agent, against the toxic effect of ionizing radiation (IR) on kidney tissues ...
Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity
(Wroclaw Medical Univ, 2018)
Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ...
Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury
(Springer, 2018)
Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ...
Effects of gadolinium-based contrast agents on submandibular gland tissue in rats
(Springer, 2018)
The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on ...
Effects of gadolinium-based MRI contrast agents on liver tissue
(Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...
The effect of gadolinium-based contrast agents on rat testis
(Wiley, 2018)
Previous studies have reported that repeated administrations of linear gadolinium-based contrast agents lead to their accumulation in the brain and other tissues in individuals with normal renal functions. the purpose of ...
Effects of infliximab against methotrexate toxicity in splenic tissue via the regulation of CD3, CD68, and C200R in rats
(Karger, 2018)
Methotrexate (MTX), which has been used in clinical practice for approximately 70 years, is still widely employed in the treatment of rheumatoid arthritis (RA), psoriasis, and cancer. Although MTX toxicity causes nephrotoxicity, ...
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
(Elsevier, 2019)
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ...
The effects of N-acetylcysteine on radiotherapy-induced small intestinal damage in rats
(Sage Publications Ltd, 2019)
Six million cancer patients worldwide receive radiotherapy, either alone or in combination with other cancer treatments annually. the purpose of this study was to investigate, at the structural and molecular levels, the ...