Yazar "Çiçek, Ayşegül Çopur" için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Distribution of beta-lactamase genes among carbapenem-resistant klebsiella pneumoniae strains isolated from patients in Turkey
Iraz, Meryem; Düzgün, Azer Özad; Sandallı, Cemal; Doymaz, Mehmet Ziya; Akkoyunlu, Yasemin; Saral, Ayşegül; Peleg, Anton Y.; Özgümüş, Osman Birol; Beriş, Fatih Şaban; Karaoğlu, Hakan; Çiçek, Ayşegül Çopur (Korean Soc Laboratory Medicine, 2015)Background: the emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the beta-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ... -
Does prolidase indicate worsening of Hepatitis B infection?
Duygu, Fazilet; Aksoy, Nurten; Çiçek, Ayşegül Çopur; Bütün, İlknur; Ünlü, Şebnem (John Wiley & Sons Inc, 2013)Background Hepatitis B infection is a health problem that affects more than 400 million people all over the world. We aimed to evaluate the usability of prolidase enzyme that plays an important role in collagen synthesis. ... -
Effect of mazEF, higBA and relBE toxin-antitoxin systems on antibiotic resistance in Pseudomonas aeruginosa and Staphylococcus isolates
Coşkun, Umut Safiye Say; Çiçek, Ayşegül Çopur; Kılınç, Çetin; Güçkan, Rıdvan; Dağcıoğlu, Yelda; Demir, Osman; Sandallı, Cemal (Med Coll Malawi, 2018)Background A toxin-antitoxin (TA) system is a set of two or more closely linked genes that are encoded as a poison and a corresponding antidote on a protein. in typical bacterial physiology, an antitoxin binds to a toxin ... -
Evaluating molecular epidemiology of carbapenem non-susceptible Klebsiella pneumoniae isolates with MLST, MALDI-TOF MS, PFGE
İbik, Yunus Emre; Ejder, Nebahat; Sevim, Elif; Rakıcı, Erva; Tanrıverdi, Elif Seren; Çiçek, Ayşegül Çopur (SpringerNature, 2023)Background This study aimed to evaluate antibiotic resistance genes and virulence genes and the clonal relationship of the carbapenem-nonsusceptible Klebsiella pneumoniae strains by molecular methods which are isolated ... -
Evaluation of the carbapenem inactivation method for detection of carbapenemase-producing gram-negative bacteria in comparison with the RAPIDEC CARBA NP
Aktaş, Elif; Malkoçoğlu, Gülşah; Otlu, Barış; Çiçek, Ayşegül Çopur; Kulah, Canan; Cömert, Füsun; Sandallı, Cemal; Gürsoy, Nafia Canan; Erdemir, Duygu; Bulut, Mehmet Emin (Mary Ann Liebert, Inc, 2017)Timely detection of carbapenemases by both phenotypic and genotypic methods is essential for developing strategies to control the spread of infections by carbapenem-resistant isolates and related morbidity and mortality. ... -
High prevalence of NDM metallo-β-lactamase among ESBL-producing Escherichia coli İsolates
Çetinkol, Yeliz; Sandallı, Cemal; Çalgın, Mustafa Kerem; Yıldırım, Arzu Altunçekiç; Akyıldız, Esma; Karaman, Esin; Çiçek, Ayşegül Çopur (Akademiai Kiado Zrt, 2017)Resistance to beta-lactams in Enterobacteriaceae has been increasing worldwide. This study aimed to determine the frequency of beta-lactamase genes and antibiotic resistance rates of 140 extended-spectrum beta-lactamase ... -
Investigation of class 1 integrons with antibiotic resistance genes in multidrug-resistant acinetobacter baumannii strains and determination of plant extract effects on multidrug-resistant isolates
Saral, Ayşegül; Cinemre, Sedanur; Okumuş, Funda; Akar, Zeynep; Çiçek, Ayşegül Çopur; Düzgün, Azer Özad (Soc Stiinte Farmaceutice Romania, 2021)This study aimed to investigate the presence of resistance genes in multidrug-resistant A. baumannii isolates as well as to determine the antibacterial activity of selected plant extracts against isolates. 41 strains were ... -
Investigation of the clonal associations in Acinetobacter Baumannii strains isolated from the respiratory samples of patients in a tertiary research hospital
Özyurt, Songül; Kostakoğlu, Uğur; Yıldız, İlknur Esen; Ertürk, Ayşe; Sönmez, Emine; Şahin, Ünal; Çiçek, Ayşegül Çopur (Wolters Kluwer Medknow Publications, 2020)Objective: the blaOXA resistance genes and ISAba1 were examined in 70 samples from lower respiratory tract of hospitalized patients. Materials and Methods: of the 67 isolates obtained, almost half (46.3%) of them were from ... -
Kinetic characterization of GES-22 beta-lactamase harboring the M169L clinical mutation
Saral, Ayşegül; Leonard, David A.; Düzgün, Azer Özad; Çiçek, Ayşegül Çopur; June, Cynthia M.; Sandallı, Cemal (Japan Antibiotics Research Assoc, 2016)The class A p-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a ... -
Molecular characterisation and control of Acinetobacter baumannii isolates resistant to multi-drugs emerging in inter-intensive care units
Ertürk, Ayşe; Çiçek, Ayşegül Çopur; Gümüş, Aziz; Cüre, Erkan; Şen, Ahmet; Kurt, Aysel; Karagöz, Alper; Aydoğan, Nebahat; Sandallı, Cemal; Durmaz, Rıza (BmcBMC, 2014)Background: A nosocomial outbreak of Acinetobacter baumannii (AB) infections occurred among intensive care units (ICU) (surgery, medical, cardiovascular surgery, coronary unit) of Recep Tayyip Erdogan University Medical ... -
Molecular epidemiological analysis of integron gene cassettes and tetA/tetB/tetD gene associations in Escherichia coli strains producing extended-spectrum beta-lactamase (ESBL) in urine cultures
Çiçek, Ayşegül Çopur; Şemen, Vicdan; Ejder, Nebahat Aydoğan; Gündoğdu, Deniz Zehra Ulusan; Kalcan, Sema Koçyiğit; Köse, Fatma Tufan; Özgümüş, Osman Birol (Wroclaw Medical University, 2021)Background. Epidemiological studies of tetracycline (TE) resistance genes and integron gene cassettes, particularly in urine samples, are limited in Turkey. Objectives. To investigate antibiotic susceptibility profiles, ... -
A multicenter evaluation of blood culture practices, contamination rates, and the distribution of causative bacteria
Altındiş, Mustafa; Koroğlu, Mehmet; Demiray, Tayfur; Dal, Tuba; Özdemir, Mehmet; Şengil, Ahmet Zeki; Atasoy, Ali Rıza; Doğan, Metin; Çiçek, Ayşegül Çopur; Ece, Gülfem; Kaya, Selçuk; Iraz, Meryem; Gültepe, Bilge Sümbül; Temiz, Hakan; Demirkan, İdris; Aksaray, Sebahat; Çetinkol, Yeliz; Şahin, İdris; Güdücüoğlu, Hüseyin; Kılıç, Abdullah; Koçoğlu, Esra; Gülhan, Barış; Karabay, Oğuz (Ahvaz Jundishapur Univ Med Sci, 2016)Background: the prognostic value of blood culture testing in the diagnosis of bacteremia is limited by contamination. Objectives: in this multicenter study, the aim was to evaluate the contamination rates of blood cultures ... -
Nationwide study of Escherichia coli producing extended-spectrum beta-lactamases TEM, SHV and CTX-M in Turkey
Çiçek, Ayşegül Çopur; Saral, Ayşegül; Düzgün, Azer Özad; Yaşar, Ekrem; Çizmeci, Zeynep; Balcı, Pervin Özlem; Sarı, Fatma; Fırat, Mehmet; Altıntop, Yasemin Ay; Ak, Sibel; Çalışkan, Ahmet; Yıldız, Nazan; Sancaktar, Metin; Budak, Emine Esra; Ertürk, Ayşe; Özgüm, Osman Birol; Sandallı, Cemal (Nature Publishing Group, 2013)Four hundred and forty extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli isolates were collected from 10 different hospitals in Turkey between 2011 and 2012. Clinical specimens consisted of urine (80.45%), ... -
A Novel integron gene cassette harboring VIM-38 Metallo-beta-lactamase in a clinical pseudomonas aeruginosa isolate
Beriş, Fatih Şaban; Akyıldız, Esma; Düzgün, Azer Özad; Coşkun, Umut Safiye Say; Sandallı, Cemal; Çiçek, Ayşegül Çopur (Korean Soc Laboratory Medicine, 2016)Dear Editor, Multidrug resistance of Pseudomonas aeruginosa has been attributed to both intrinsic and acquired antibiotic-resistance mechanisms. Multidrug-resistant (MDR) P. aeruginosa isolates have become a serious ... -
OXA- and GES-type beta-lactamases predominate in extensively drug-resistant Acinetobacter baumannii isolates from a Turkish University Hospital
Çiçek, Ayşegül Çopur; Saral, Ayşegül; Iraz, Meryem; Ceylan, Ayşenur; Düzgün, Azer Özad; Peleg, Anton Y.; Sandallı, Cemal (Elsevier Sci Ltd, 2014)We determined the antibiotic susceptibility and genetic mechanisms of resistance in clinical strains of Acinetobacter baumannii from Istanbul, Turkey. A total of 101 clinical strains were collected between November 2011 ... -
Prevalence and genotype distribution of rotaviruses in children with gastroenteritis in Rize province
Dereci, Selim; Çiçek, Ayşegül Çopur; Acar, Sümeyra Savaş; Bakkaloğlu, Zekiye; Özkasap, Serdar; Kanber, Kadri; Hacısalihoğlu, Şadan; Albayrak, Yücehan; Durmaz, Rıza (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2015)Determination of the distribution of rotavirus genotypes is essential for understanding the epidemiology of this virus responsible for nearly half a million of deaths in patients with gastroenteritis worldwide. in the ... -
Prevalence of rotavirus genotypes in children younger than 5 years of age before the introduction of a universal rotavirus vaccination program: Report of Rotavirus Surveillance in Turkey
Durmaz, Rıza; Kalaycıoğlu, Atia Taner; Acar, Sümeyra; Bakkaloğlu, Zekiye; Karagöz, Alper; Korukluoğlu, Gülay; Ertek, Mustafa; Torunoğlu, Mehmet Ali; Gökahmetoğlu, Selma; Öztürk, Adnan; Bayram, Ayşen; Araz, Nilgün Çöl; Bacalan, Fatma; Gündeşlioğlu, Özlem Özgür; Yaşar, Ekrem; Altındiş, Mustafa; Bükülmez, Ayşegül; Öngen, Betigül; Somer, Ayper; Bayraktar, Banu; Karabulut, Nazan Dalgıç; Uslu, Hakan; Aktaş, Ferda; Kılıç, Ömer; Çiçek, Ayşegül Çopur; Dereci, Selim; Aksaray, Sebahat; Nuhoğlu, Çağatay; Adaleti, Rıza; Bozdayı, Gülendam; Tezer, Hasan; Mutlu, Derya; Yılmaz, Aygen; Şekercioğlu, Ali Osman; Durmaz, Gül; Hacımustafaoğlu, Mustafa; Özakın, Cüneyt; Çelebi, Solmaz; Tezcan, Seda; Aslan, Gönül; Ark, Ersin; Sözen, Ebru; Tanır, Gönül; Özkan, Şengül; Zararsız, Hülya; Çelik, Ümit; Çetin, Emel Sesli; Öz, Metehan; Devrim, İlker; Bayram, Süleyman; Sorguç, Yelda; İnce, Erdal; Güriz, Haluk; Kocabaş, Bilge; Güdücüoğlu, Hüseyin; Tuncer, Oğuz; Aydın, Faruk; Erduran, Erol; Çetinkaya, Zafer; Vahaboğlu, Haluk; Kelesyan, Figen Temel; Anıl, Murat; Yılmaz, Dilek; Çiçek, Candan; Saz, Eylem Ulaş; Kurugöl, Zafer; Eroğlu, Cafer; Güzel, Ahmet; Feyzioğlu, Bahadır; Emiroğlu, Melike; Zeyrek, Fadile Yıldız; Çakmak, Alpay; Kocabaş, Emine; Selimoğlu, Ayşe; Kuzucu, Çiğdem; Sosyal, Ahmet; Bakır, Mustafa; Yağcı, Ayşegül; Uyar, Yavuz; Özlü, Ahmet; Temel, Fehminaz (Public Library of Science, 2014)Background: Group A rotaviruses are the most common causative agent of acute gastroenteritis among children less than 5 years of age throughout the world. This sentinel surveillance study was aimed to obtain baseline data ... -
Rize 82.Yıl Devlet Hastanesi'nde bir yıllık sürede kan kültürlerinden izole edilen mikroorganizmalar ve antibiyotiklere duyarlılıkları
AMAÇ: Şubat 2010 ve Şubat 2011 tarihleri arasında Rize 82.Yıl Devlet Hastanesi Mikrobiyoloji Laborotuvarına gönderilen kan kültür örneklerinden izole edilen çeşitli mikroorganizmalar ve antibiyotiklere duyarlılıkları ... -
Screening of antimicrobial resistance genes and epidemiological features in hospital and community-associated Carbapenem-Desistant Pseudomonas Aeruginosa infections
Çiçek, Ayşegül Çopur; Ertürk, Ayşe; Ejder, Nebahat; Rakıcı, Erva; Kostakoğlu, Uğur; Yıldız, İlknur Esen; Özyurt, Songül; Sönmez, Emine (Dove Medical Press Ltd., 2021)Introduction: Researching carbapenem-resistant isolates enables the identification of carbapenemase-producing bacteria and prevents their spread. Methods: P. aeruginosa isolates were recovered from Medicine Faculty of ... -
Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing
Yashar, Meltem; Başarır, Kerem E.; Tanrıverdi, Elif Seren; Celep, Selçuk; Sirekbasan, Leyla; Rakıcı, Erva; Ejder, Nebahat; Müsellim, Eda; Çiçek, Ayşegül Çopur; Yılmaz, Mesut (Elsevier, 2023)Background: Nosocomial Stenotrophomonas maltophilia-related cases are rising and pose a threat to immunocompromised patients. Twelve patients from our pediatric intensive care unit (PICU) presented with S maltophilia-associated ...