Yazar "Cüre, Erkan" için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Infliximab modulates cisplatin-induced hepatotoxicity in rats
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Kırbaş, Aynur; Tümkaya, Levent; Yılmaz, Arif; Türkyılmaz, Ayşegül Küçükali; Sehitoğlu, İbrahim; Yüce, Süleyman (Galenos Publ, 2016)Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ... -
Investigation of surfactant protein-D and interleukin-6 levels in patients with blunt chest trauma with multiple rib fractures and pulmonary contusions: a cross-sectional study in Black Sea Region of Turkey
Kurt, Aysel; Türüt, Hasan; Aıipayam, Ahmet; Kırbaş, Aynur; Yüce, Süleyman; Cüre, Medine Cumhur; Cüre, Erkan (Bmj Publishing Group, 2016)Objective: Multiple rib fractures (RFs) and pulmonary contusions (PCs), with resulting systemic lung inflammation, are the most common injuries caused by blunt chest trauma (BCT) in motor vehicle accidents. This study ... -
Is adalimumab protective in ischemia‐reperfusion injury in lung?
Kurt, Aysel; Tümkaya, Levent; Kalkan, Yıldıray; Türüt, Hasan; Cüre, Medine Cumhur; Cüre, Erkan; Şehitoğlu, İbrahim; Bilgin, Hacer; Usta, Mustafa (Mashhad University of Medical Sciences, 2015)Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I?R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor?alpha (TNF??) inhibitor agent. We aimed ... -
Is increasing the dose of entecavir effective in partial virological responders?
Ertürk, Ayşe; Akdoğan, Remzi Adnan; Parlak, Emine; Cüre, Erkan; Cüre, Medine Cumhur; Öztürk, Çınar (Dove Medical Press Ltd., 2014)Objective: To analyze the effect of increasing Entecavir (ETV) dosage in patients with chronic hepatitis B (CHB) who partially responded to ETV after 1 year. Methods: Twenty-three hepatitis B e antigen (HBeAg)-positive and ... -
Is the mean platelet volume predictive of hip fractures in the elderly?
Cüre, Erkan; Balık, Mehmet Sabri; Cüre, Medine Cumhur; Güvercin, Yılmaz; Erkut, Adem; Yüce, Süleyman; Keskin, Davut (Korean Soc Laboratory Medicine, 2013)Mean platelet volume (MPV) reflects the size of platelets and is accepted as a marker of platelet function. Platelets secrete and express a large number of substances that are crucial mediators of coagulation, inflammation, ... -
Mean platelet volume and vitamin D level
Cüre, Medine Cumhur; Cüre, Erkan; Yüce, Süleyman; Yazıcı, Tarkan; Karakoyun, İnanç; Efe, Hasan (Korean Soc Laboratory Medicine, 2014)Background: Vitamin D deficiency and a high mean platelet volume (MPV) are related to cardiovascular disease. We investigated whether vitamin D deficiency is associated with high MPV. Methods: This study included 434 ... -
Molecular characterisation and control of Acinetobacter baumannii isolates resistant to multi-drugs emerging in inter-intensive care units
Ertürk, Ayşe; Çiçek, Ayşegül Çopur; Gümüş, Aziz; Cüre, Erkan; Şen, Ahmet; Kurt, Aysel; Karagöz, Alper; Aydoğan, Nebahat; Sandallı, Cemal; Durmaz, Rıza (BmcBMC, 2014)Background: A nosocomial outbreak of Acinetobacter baumannii (AB) infections occurred among intensive care units (ICU) (surgery, medical, cardiovascular surgery, coronary unit) of Recep Tayyip Erdogan University Medical ... -
Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome
Şahin, Figen Kır; Şahin, Serap Baydur; Ural, Ülkü Mete; Cüre, Medine Cumhur; Şentürk, Şenol; Tekin, Yeşim Bayoğlu; Balık, Gülşah; Cüre, Erkan; Yüce, Süleyman; Kırbaş, Aynur (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2015)Obesity, insulin resistance (IR), inflammation, and hyperandrogenism may lead to polycystic ovary syndrome (PCOS) and hypertension. Nesfatin-1 (N1) may be related to IR, obesity, and hypertension. Furthermore, a vitamin D ... -
Novel myokine: irisin may be an independent predictor for subclinic atherosclerosis in Behcet's disease
İçli, Abdullah; Cüre, Erkan; Cüre, Medine Cumhur; Uslu, Ali Uğur; Balta, Şevket; Arslan, Şevket; Sakız, Davut; Küçük, Adem (Bmj Publishing Group, 2016)Behcet's disease (BD) is a vasculitic and inflammatory disease causing endothelial dysfunction. Irisin is a metabolic hormone related to insulin resistance and endothelial functions. in this study, we investigated the ... -
Profound hypoglycemia-induced by vaccinium corymbosum juice and laurocerasus fruit
Aktan, Ahmet Hamdi; Özçelik, Abdullah; Cüre, Erkan; Cüre, Medine Cumhur; Yuce, Suleyman (Medknow Publications & Media Pvt Ltd, 2014)An emergency intervention was performed in a 75-year-old male patient with hypoglycemic attack and blackout. Although he was diagnosed with prediabetes before 2 years, he did not take any anti-diabetic drug or follow dietary ... -
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Tümkaya, Levent; Aydın, İbrahim; Kırbaş, Aynur; Efe, Hasan; Kurt, Aysel; Yüce, Süleyman (Wroclaw Medical Univ, 2016)Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ... -
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
Kurt, Aysel; Tümkaya, Levent; Yüce, Süleyman; Türüt, Hasan; Cüre, Medine Cumhur; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Pusuroğlu, Gökhan; Cüre, Erkan (Mashhad Univ Med Sciences, 2016)Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ... -
Protective effect of infliximab against carbon tetrachloride-induced hepatotoxicity
Şehitoğlu, İbrahim; Tümkaya, Levent; Bedir, Recep; Özer, Ender; Cüre, Medine Cumhur; Yüce, Süleyman; Kalkan, Yıldıray; Cüre, Erkan (Begell House Inc, 2015)Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ... -
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
Aydın, İbrahim; Kalkan, Yıldıray; Özer, Ezgi Demir; Yücel, Ahmet Fikret; Pergel, Ahmet; Cüre, Erkan; Cüre, Medine Cumhur; Şahin, Dursun Ali (Verduci Publisher, 2014)OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Kalkan, Yıldıray; Yılmaz, Arif; Yüce, Süleyman (Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
Protective effects of infliximab on lung injury induced by methotrexate
Kurt, Aysel; Tümkaya, Levent; Türüt, Hasan; Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Şehitoğlu, İbrahim; Acıpayam, Ahmet (Elsevier Espana Slu, 2015)Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ... -
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
Erkut, Adem; Cüre, Medine Cumhur; Kalkan, Yıldıray; Balık, Mehmet Sabri; Güvercin, Yılmaz; Yaprak, Esra; Yüce, Süleyman; Şehitoğlu, İbrahim; Cüre, Erkan (Verduci Publisher, 2016)OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ... -
The relationship between atherogenic index and carotid artery atherosclerosis in familial mediterranean fever: A pilot study
İçli, Abdullah; Cüre, Erkan; Uslu, Ali Uğur; Sakız, Davut; Cüre, Medine Cumhur; Özuçan, Miyase; Baykara, Rabia Aydoğan; Karakoyun, Ahmet; Balta, Şevket; Öztürk, Cengiz; Arslan, Şevket; Küçük, Adem (Sage Publications Inc, 2017)Familial Mediterranean fever (FMF) is a disease characterized by chronic inflammation. Atherogenic index of plasma (AIP) is a logarithmic value of the triglyceride to high-density lipoprotein cholesterol ratio and it is a ... -
Relationships between C-kit expression and mean platelet volume in benign, preneoplastic and neoplastic endometrium
Şehitoğlu, İbrahim; Bedir, Recep; Ural, Ülkü Mete; Güçer, Hasan; Yurdakul, Cüneyt; Cüre, Medine Cumhur; Cüre, Erkan; Yüce, Süleyman; Şahin, Figen Kır (Asian Pacific Organization for Cancer Prevention, 2015)Background: c-Kit is a proto-oncogene that encodes a tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker for demonstrating thrombocyte function. We aimed to investigate whether c-kit is expressed ... -
Rize ilinde erişkin yaş gruplarında Hepatit A seroprevalansı
Amaç: Bu çalışmada Rize ilinde yaş grupları için Hepatit A (HAV) seroprevalansını araştırmayı amaçladık. Bunun yanısıra, “Genişletilmiş Ulusal Bağışıklama Programı’nın” hepatit A aşısı eklenerek başlatıldığı sürecin öncesinde ...