Kurum Yazarı "Kırbaş, Aynur" TF, Temel Tıp Bilimleri Bölümü Koleksiyonu İçin Listeleme
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Infliximab modulates cisplatin-induced hepatotoxicity in rats
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Kırbaş, Aynur; Tümkaya, Levent; Yılmaz, Arif; Türkyılmaz, Ayşegül Küçükali; Sehitoğlu, İbrahim; Yüce, Süleyman (Galenos Publ, 2016)Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ... -
Investigation of surfactant protein-D and interleukin-6 levels in patients with blunt chest trauma with multiple rib fractures and pulmonary contusions: a cross-sectional study in Black Sea Region of Turkey
Kurt, Aysel; Türüt, Hasan; Aıipayam, Ahmet; Kırbaş, Aynur; Yüce, Süleyman; Cüre, Medine Cumhur; Cüre, Erkan (Bmj Publishing Group, 2016)Objective: Multiple rib fractures (RFs) and pulmonary contusions (PCs), with resulting systemic lung inflammation, are the most common injuries caused by blunt chest trauma (BCT) in motor vehicle accidents. This study ... -
Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?
Tekin, Yeşim Bayoğlu; Güven, Süleyman; Kırbaş, Aynur; Kalkan, Yıldıray; Tümkaya, Levent; Güven, Emine Seda Güvendağ (Elsevier Science Bv, 2015)Objective: Resveratrol, a phytoalexin polyphenol, has anti-angiogenic, antioxidant, anti-inflammatory properties. We aimed to compare the anti-inflammatory and anti-angiogenic effects of resveratrol and leuprolide acetate ... -
Is SCUBE1 helpful to predict the arterial thrombotic risk in patients with multiple myeloma: a preliminary study
Akdoğan, Emin; Ayaz, Teslime; Kırbaş, Aynur; Rakıcı, Halil (Lithographia, 2019)Background: Signal peptide-CUB-EGF-like domain-containing protein I (SCUBE1) is expressed in vascular endothelium and human platelets. SCUBE I levels are increased in acute arterial thrombosis. Multiple myeloma patients ... -
Lisinopril attenuates renal oxidative injury in L-NAME-induced hypertensive rats
Öktem, Faruk; Kırbaş, Aynur; Armağan, Abdullah; Kuybulu, Ayça Esra; Yılmaz, H. Ramazan; Özguner, Fehmi; Uz, Efkan (Springer, 2011)Hypertension and related oxidative stress are involved in the pathogenesis of any renal diseases. Angiotensin-converting enzyme inhibitors have multi-directional renoprotective effects. In this study, we aimed to investigate ... -
Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome
Şahin, Figen Kır; Şahin, Serap Baydur; Ural, Ülkü Mete; Cüre, Medine Cumhur; Şentürk, Şenol; Tekin, Yeşim Bayoğlu; Balık, Gülşah; Cüre, Erkan; Yüce, Süleyman; Kırbaş, Aynur (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2015)Obesity, insulin resistance (IR), inflammation, and hyperandrogenism may lead to polycystic ovary syndrome (PCOS) and hypertension. Nesfatin-1 (N1) may be related to IR, obesity, and hypertension. Furthermore, a vitamin D ... -
A novel biomarker in the diagnosis of parapneumonic effusion: neutrophil gelatinase-associated lipocalin
Gümüş, Aziz; Özkaya, Şevket; Özyurt, Songül; Çınarka, Halit; Kırbaş, Aynur; Şahin, Ünal; Ece, Ferah (BioMed Central Ltd., 2014)Background: The protein neutrophil gelatinase-associated lipocalin (NGAL) is a mediator synthesized and released by neutrophils. Its physiological function is as yet unclear. Levels in blood increase in several inflammatory ... -
Paraoxonase and arylesterase activity and total oxidative/anti-oxidative status in patients with idiopathic Parkinson's disease
Kırbaş, Aynur; Kırbaş, Serkan; Cüre, Medine Cumhur; Tüfekçi, Ahmet (Elsevier Sci Ltd, 2014)This study investigated serum paraoxonase (PON1) and arylesterase activity along with determination of oxidative status via measurement of total oxidant status (TOS), total anti-oxidant status (TAS) and oxidative stress ... -
Plasma catestatin concentration is independently correlated with high-density lipoprotein cholesterol levels in untreated hypertensive patients
Durakoğlugil, Murtaza Emre; Ayaz, Teslime; Kocaman, Sinan Altan; Kırbaş, Aynur; Durakoğlugil, Tuğba; Erdoğan, Turan; Çetin, Mustafa; Şahin, Osman Zikrullah; Çiçek, Yüksel (Elsevier Science Inc, 2013)Purpose Catestatin (CST), a novel peptide derived from Chromogranin A, has diverse cardiovascular actions in addition to diminished sympathoadrenal flow. We intended to investigate metabolic and vascular associations of CST. -
Plasma homocysteine levels in dry eye patients
Şekeryapan, Berrak; Öner, Veysi; Kırbaş, Aynur; Türkyılmaz, Kemal; Durmuş, Mustafa (Lippincott Williams & Wilkins, 2013)Purpose: To compare plasma homocysteine levels between patients with dry eye disease and normal control subjects. Methods: Plasma homocysteine (enzyme immunoassay), vitamin B12, and folate levels were determined in 38 ... -
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Tümkaya, Levent; Aydın, İbrahim; Kırbaş, Aynur; Efe, Hasan; Kurt, Aysel; Yüce, Süleyman (Wroclaw Medical Univ, 2016)Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Kalkan, Yıldıray; Yılmaz, Arif; Yüce, Süleyman (Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
The relation between carotid intima media thickness and serum osteoprotegerin levels in nonalcoholic fatty liver disease
Ayaz, Teslime; Kırbaş, Aynur; Durakoğlugil, Tuğba; Durakoğlugil, Murtaza Emre; Şahin, Serap Baydur; Şahin, Osman Zikrullah; Kırvar, Abdulkadir; Taşçı, Filiz (Mary Ann Liebert, Inc, 2014)Aim: This study was designed to evaluate carotid intima media thickness (CIMT) and serum osteoprotegerin (OPG) levels in nonalcoholic fatty liver disease (NAFLD) in comparison to healthy controls and to investigate factors ... -
The relationship between bone formation and functional status in symptomatic lumbar spinal stenosis
Devrimsel, Gül; Küçükali, Ayşegül Türkyılmaz; Yıldırım, Murat; Kırbaş, Aynur (Bayçınar Tıbbi Yayıncılık, 2014)Amaç: Çalışmamızdaki amacımız, semptomatik lomber spinal stenozu (LSS) olan hastalarda kemik formasyonu ile fonksiyonel durum arasındaki ilişkiyi değerlendirmektir. Gereç ve Yöntemler: Çalışmaya, polikliniğine başvuran ... -
Relationship between pulse wave velocity and serum YKL-40 level in patients with early rheumatoid arthritis
Türkyılmaz, Ayşegül Küçükali; Devrimsel, Gül; Kırbaş, Aynur; Çiçek, Yüksel; Karkucak, Murat; Çapkın, Erhan; Gökmen, Ferhat (Springer Heidelberg, 2013)Subclinical atherosclerosis has been demonstrated in patients with early rheumatoid arthritis (ERA) without any signs of cardiovascular disease (CVD). the aim of this study was to investigate the relationship between serum ... -
The relationship between serum YKL-40 levels and arterial stiffness in patients with ankylosing spondylitis
Türkyılmaz, Ayşegül Küçükali; Devrimsel, Gül; Beyazal, Münevver Serdaroğlu; Kırbaş, Aynur; Çiçek, Yüksel Gülen; Çapkın, Erhan; Karkucak, Murat; Gökmen, Ferhat (Publisaude-Edicoes Medicas Lda, 2017)Objective: Serum YKL-40 plays roles in inflammatory and vascular processes. Our aim was to evaluate serum YKL-40 levels in patients with ankylosing spondylitis (AS) and to investigate their potential relationship with ... -
Response to a letter to the editor entitled "low serum B12 level does not mean vit. B12 deficiency-problems related to the diagnosis of vitamin B12 deficiency"
Öner, Veysi; Türkylmaz, Kemal; Türkyılmaz, Ayşegül Küçükali; Kırbaş, Aynur; Kırbaş, Serkan; Şekeryapan, Berrak (Taylor & Francis Inc, 2014)We thank Dr Grzybowski1 for the interest he has shown in our article entitled ‘‘Evaluation of peripapillary retinal nerve fiber layer thickness in patients with vitamin B12 deficiency using spectral domain optical ... -
The role of hypoxia at primary dysmenorrhea, utilizing a novel hypoxia marker-scubel
Tekin, Yeşim Bayoğlu; Güven, Emine Seda Güvendağ; Kırbaş, Aynur; Üstüner, Işık; Doğan, Osman Deniz; Balık, Gülşah; Şahin, Figen Kır (Elsevier Science Inc, 2015)Study Objective: To determine the SCUBE1 levels in adolescents with primary dysmenorrhea. Design: A prospective cross-sectional study. Setting: A university hospital outpatient clinic, Rize, Turkey. Participants: A total ... -
Serum levels of homocysteine, asymmetric dimethylarginine and nitric oxide in patients with Parkinson's disease
Kırbaş, Serkan; Kırbaş, Aynur; Tufekçi, Ahmet; Cüre, Medine Cumhur; Çakmak, Sevim; Yazıcı, Tarkan; Cüre, Erkan (Taylor & Francis Ltd, 2016)Objectives: Endothelial dysfunction has been implicated as a crucial event in the development of several neurodegenerative diseases. the aim of this study was to investigate the serum homocysteine, asymmetric dimethylarginine ... -
Serum paraoxonase and arylesterase activity and oxidative status in patients with multiple sclerosis
Kırbaş, Aynur; Kırbaş, Serkan; Anlar, Ömer; Efe, Hasan; Yılmaz, Adnan (Elsevier Sci Ltd, 2013)The aim of this study was to investigate serum paraoxonase and arylesterase activities, and to determine oxidative status via the measurement of total oxidant status (TOS), total antioxidant status (TAS) and the oxidative ...