Başlık için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 576, listelenen: 425-444
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The prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast carcinomas
(Elsevier, 2023)Background and objective: The prognostic importance of lymphoid cells in the tumor microenvironment and their effect on treatment response have been demonstrated in many cancer types. However, there are limited studies on ... -
Prognostic value of hematological parameters
(Derman Medical Publ, 2018)Aim: Acute bacterial and viral infections are usually associated with elevations of the mean platelet volume. We correlated infection with influenza changes in mean platelet volume (MPV), neutrophil-to-lymphocyte ratio ... -
Prolidase activity and oxidative stress in patients with major depressive disorder
(Medicinska Naklada, 2014)Background: the aim of the current study was to determine whether the serum prolidase levels are associated with the etiopathogenesis of depression. Subjects and methods: This study included 29 patients with major depressive ... -
Prolidase activity and oxidative stress in patients with schizophrenia: A preliminary study
(Pakistan Medical Assoc, 2015)Objective: To determine whether serum prolidase levels are associated with the etiopathogenesis of schizophrenia. Methods: the study was conducted at the psychiatry outpatient clinics of the University Hospitals of Recep ... -
A promoter polymorphism in the PON1 gene is associated with essential hypertension
(Lippincott Williams & Wilkins, 2015)Objective: Increased vascular oxidative stress, the main risk factor of cardiovascular diseases, is seen as a role in the pathophysiology of essential hypertension. Genetic factors also play an important role in the ... -
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
(Wroclaw Medical Univ, 2016)Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ... -
Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats
(Sage Publications Ltd, 2018)Paracetamol (P), one of the most popular and commonly used analgesic and antipyretic agents, causes hepatotoxicity in overdoses. Amlodipine (AML), an L-type calcium channel blocker, has been shown to have anti-inflammatory ... -
Protective effect of astaxanthin against cisplatin-induced gastrointestinal toxicity in rats
(Springer Wien, 2022)Background the aim of the present study was to demonstrate astaxanthin's attenuating effects against cisplatin (CIS)-induced gastrointestinal toxicity in a rat model. Methods Thirty-two Wistar rats (weight 200-250 g) were ... -
The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)Purpose: the aim of this experimental study was to investigate the antioxidant effects of astaxanthin against cisplatin-induced nephrotoxicity in rats. Methods: Forty-eight male Sprague-Dawley rats weighing 264.83 +/- 7.39 ... -
The protective effect of astaxanthin on cisplatin-induced ototoxicity
(Wroclaw Medical Univercity, 2021)Background. Promising studies have been conducted with many substances to reduce the ototoxic effects of cisplatin, but there is no treatment that completely eliminates the ototoxic effect. Objectives. To determine the ... -
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
(Mashhad Univ Med Sciences, 2016)Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ... -
Protective effect of infliximab against carbon tetrachloride-induced hepatotoxicity
(Begell House Inc, 2015)Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ... -
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
(Verduci Publisher, 2014)OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
Protective effect of Panax ginseng against serum biochemical changes and apoptosis in kidney of rats treated with gentamicin sulphate
(Springer Link, 2012)The protective effects of Panax ginseng (PG) on gentamicin sulphate (GS) induced acute nephrotoxicity were investigated in rats. A total of 32 adult Sprague- Dawley rats were randomly divided into 4 equal groups and treated ... -
Protective effect of Panax ginseng against serum biochemical changes and apoptosis in liver of rats treated with carbon tetrachloride (CCl 4)
(Elsevier, 2011)The purpose of this study was to investigate possible beneficial effects of Panax ginseng (PG) on carbon tetrachloride (CCl 4)-induced acute hepatotoxicity in rats. CCl 4 challenge elevated serum enzyme activities of liver ... -
Protective effect of resveratrol against methotrexate-induced oxidative stress in the small intestinal tissues of rats
(E-Century Publishing Corp, 2015)The effect of resveratrol on the damage induced by methotrexate (MTX) in rat duodenum and jejunum tissue was investigated and evaluated in comparison with famotidine. the rats were divided into four groups as healthy group ... -
The protective effect of syringic acid on ischemia injury in rat brain
(2015)Background/aim: Brain ischemia and treatment are important topics in neurological science. Free oxygen radicals and inflammation formed after ischemia are accepted as the most significant causes of damage. Currently there ... -
Protective effect of tea grape extract on cisplatin-induced muscle atrophy: A morphological study
(Kowsar Publ, 2018)Background: Even though Cisplatin (Cis) is known to be organotoxic, it is used in neoplastic chemotherapy. in skeletal muscles, the toxic effect manifests as atrophy. Objectives: the tea grape extract (TGE) is a sort of ... -
Protective effect of thymoquinone in preventing trauma-related damage: an experimental study
(Taylo & Francis Ltd., 2021)Background Secondary injury is a potentially modifiable factor of outcome in traumatic brain injury. This study aimed to investigate thymoquinone's effects on trauma-induced neuronal damage. Methods Eighteen adult female ...
