Yazar "Birdane, Alparslan" için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Association and haplotype analysis of the PON1, ITGB3 and CYP3A4 genes, strong candidates for familial coronary artery disease susceptibility
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özbayer, Cansu; Ulus, Taner; Özdemir, Mahmut; Ata, Necmi; Güneş, Hasan Veysi (2023)Objective: Genetic predisposition is very common among the patients with coronary artery disease (CAD), a complex and multifactorial disease. Our objective was to determine the possible association between the most ... -
Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension
Coşan, Didem Turgut; Çolak, Emine; Saydam, Faruk; Yazıcı, Hüseyin uğur; Değirmenci, İrfan; Birdane, Alparslan; Çolak, Ertuğrul; Güneş, Hasan Veysi (Taylor & Francis Inc, 2016)Human serum paraoxonase 1 (PON1) is carried by high-density lipoprotein in blood circulation and is shown to be effective in preventing oxidized phospholipids carried by low-density lipoprotein particles, thus it acts as ... -
The CYP2C19*2 and CYP2C19*17 polymorphisms play a vital role in clopidogrel responsiveness after percutaneous coronary intervention: A pharmacogenomics study
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özdemir, Mahmut; Ulus, Taner; Özbayer, Cansu; Çolak, Ertuğrul; Ata, Necmi; Güneş, Hasan Veysi (Wiley, 2017)Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor. Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current guidelines for patients undergoing ... -
Haplotype analyses of CYP2C19*2 and CYP2C19*17 genetic polymorphisms in clopidogrel non-responsiveness after percutaneous coronary intervention with stent implantation
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özdemir, Mahmut; Özbayer, Cansu; Ata, Necmi; Güneş, Hasan Veysi (Nature Publishing Group, 2018).... -
Investigation of the cyp3a4 and pon1 gene variants in turkish patients with familial coronary artery disease
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özdemir, Mahmut; Özbayer, Cansu; Ata, Necmi; Güneş, Hasan Veysi (Lippincott Williams & Wilkins, 2015)Objective: Coronary artery disease (CAD), a complex multifactorial disorder, has been suggested to be associated by the interaction of both environmental and genetic risk factors. -
A promoter polymorphism in the PON1 gene is associated with essential hypertension
Coşan, Didem Turgut; Çolak, Ertuğrul; Saydam, Faruk; Yazıcı, Hüseyin Uğur; Değirmenci, İrfan; Birdane, Alparslan; Güneş, Hüseyin Veysi (Lippincott Williams & Wilkins, 2015)Objective: Increased vascular oxidative stress, the main risk factor of cardiovascular diseases, is seen as a role in the pathophysiology of essential hypertension. Genetic factors also play an important role in the ...