Yazar "Sümer, Ayşegül" için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
Saral, Sinan; Kaya, Ali Koray; Topçu, Atilla; Öztürk, Aykut; Sümer, Ayşegül; Pınarbaş, Esra (Sakarya Üniversitesi, 2021)Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2) agonisti ve serotonin reseptör (5-HT2C) antagonisti olan antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ... -
Apelin-13 increased food intake with serum ghrelin and leptin levels in male rats
Saral, Sinan; Alkanat, Mehmet; Sümer, Ayşegül; Canpolat, Sinan (Comenius Univ, 2018)In this study, we aimed to explain the role of apelin-13 on body weight, food and water intake with serum leptin, ghrelin, neuropeptid Y (NPY) and peptid YY (PYY) levels in male rat. Thirty-two Sprague-Dawley male rats ... -
Autoantibodies against carbonic anhydrase I and II in patients with acute myeloid leukemia
Menteşe, Ahmet; Erkut, Nergiz; Demir, Selim; Yaman, Serap Özer; Sümer, Ayşegül; Doğramacı, Şeniz; Alver, Ahmet; Sönmez, Mehmet (2017)Amaç: Kanser, dünyadaki başlıca ölüm nedenlerinden birisi olup, küresel bir toplum sağlığı sorunudur. Organizmanın kendi antijenlerine karşı gelişen otoantikorlar pek çok kanser hastasının serumunda tespit edilmiştir. Son ... -
Carbonic anhydrase I and II autoantibodies in Behcet's disease
Mentese, Ahmet; Alver, Ahmet; Demir, Selim; Sümer, Ayşegül; Özer Yaman, Serap; Karkucak, Murat; Aydın Çapkın, Arzu; Us Altay, Diler; Turan, İbrahim (Publisaude-Edicoes Medicas Lda, 2017)Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a ... -
Chronic restraint stress impairs spatial memory while decreasing hippocampal BDNF levels in rats
Saral, Sinan; Sümer, Ayşegül; Kaya, Ali Koray; Öztürk, Aykut; Topçu, Atilla (İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: This study investigated the potential role of chronic restraint stress (CRS) on spatial memory, recognition memory, brain-derived neurotrophic factor (BDNF) and acetylcholine (ACh) levels in young adult rats. Material ... -
Detection of autoantibodies against carbonic anhydrase I and II in the plasma of patients with gastric cancer
Menteşe, Ahmet; Fidan, Evren; Alver, Ahmet; Demir, Selim; Yaman, Serap Özer; Sümer, Ayşegül; Fidan, Sami; Kavgacı, Halil; Turan, İbrahim (Termedia Publishing House Ltd, 2017)Cancer is the second leading cause of death and gastric cancer is the fourth most common cancer type worldwide. Investigation of autoantibodies in cancer patients has been a popular research area in recent years. the aim ... -
The effect of bee pollen on reproductive and biochemical parameters in methotrexate-induced testicular damage in adult rats
Saral, Özlem; Dokumacıoğlu, Eda; Saral, Sinan; Sümer, Ayşegül; Bulmuş, Özgür; Kaya, Şeyma Özer; Canpolat, Sinan (De Gruyter Open Ltd., 2021)Objectives: Methotrexate (MTX) is an anticancer drug used in chemotherapy. MTX was known for its toxic effects involving most of the organs including testis. Bee pollen is healthy food for human and has antioxidant effect. ... -
Effects of topiramate on adipocyte differentiation and gene expression of certain carbonic anhydrase isoenzymes
Sümer, Ayşegül; Keha, Eşref Edip; Menteşe, Ahmet; Alver, Ahmet (De Gruyter, 2020)Background: Topiramate, an antiepileptic drug, besides its known effects in neurons, is a carbonic anhydrase inhibitor and causes weight loss in treated subjects, but, the mechanisms of weight loss effect have not been yet ... -
Nutrition improves COVID-19 clinical progress
Sümer, Ayşegül; Uzun, Lütfiye Nur; Özbek, Yağmur Demirel; Tok, Hümeyra Hançer; Altınsoy, Canan (Springer, 2022)Nutrition is a basic need and is crucial for the persistence of good health. This awareness has increased since December 2019 during the pandemic that the world is still facing. The importance of nutrition in infectious ...