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Toplam kayıt 215, listelenen: 161-170
Celastrol restricts experimental periodontitis related alveolar bone loss by suppressing inflammatory cytokine response
(China Medical University, 2023)
Introduction: Periodontitis is a common chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. The host defense mechanisms are responsible for inflamatuar and destructive ...
Melatonin supports nonsurgical periodontal treatment in patients with Type 2 diabetes mellitus and periodontitis: A randomized clinical trial
(Wiley, 2023)
Background: Diabetes mellitus (DM)-associated hyperinflammatory host response significantly provokes periodontal tissue destruction. In this context, the support of nonsurgical periodontal therapy in diabetics with host ...
Inhibition of O6-methylguanine-DNA-methyltransferase (MGMT) by lomeguatrib reduces multiple myeloma cell viability and impairs DNA repair in MGMT-proficient cells
(Wiley, 2024)
The function of direct DNA damage repair protein, namely MGMT in MM, and the impact of MGMT on melphalan treatment remains unclear. We showed a significantly higher MGMT mRNA expression in CD138+ myeloma cells than in ...
The association of Sort1 expression with LDL subfraction and inflammation in patients with coronary artery disease
(Taylor & Francis Ltd., 2023)
Background: Controversial effect of sortilin on lipoprotein metabolism in the development of atherosclerosis reveals the need for more extensive research Objectives: The aim of this study was to investigate the association ...
Long-term protective effects of lamotrigine in a rat ovarian ischemia-reperfusion model
(Elsevier, 2024)
Ovarium torsion is a gynecological emergency that is common in women of reproductive age and requires early diagnosis and intervention. In this study, we aimed to investigate the long-term anatomical, histological and ...
Effects of mineral trioxide aggregate and methyl sulfonyl methane on pulp exposure via RUNX2 and RANKL pathways
(Springer Link, 2024)
The aim of this study was to determine the therapeutic effects of mineral trioxide aggregate (MTA) and methyl sulfonyl methane (MSM) on pulp damage due to pulp exposure through the RUNX2 and RANKL pathways. Seventy-two ...
Metabologenomics and network pharmacology to understand the molecular mechanism of cancer research
(Baishideng Publishing Group Inc. Tutar Y. Metabologenomics and network pharmacology to understand the molecular mechanism of cancer research. World J Clin Cases 2024; 12(3): 474-478 [PMID: 38322468 DOI: 10.12998/wjcc.v12.i3.474], 2024)
In this editorial I comment on the article "Network pharmacological and molecular docking study of the effect of Liu-Wei-Bu-Qi capsule on lung cancer" published in the recent issue of the World Journal of Clinical Cases ...
The relationship between anthropometric and metabolic risk factors and testicular function in healthy young men
(Korean Society for Reproductive Medicine, 2024)
Objective: This study investigated the relationship of anthropometric and metabolic risk factors with seminal and sex steroidal hormone parameters in a screened population of healthy males. Methods: The participants were ...
The effects of Garcinia kola and curcumin on the dorsal root ganglion of the diabetic rat after peripheral nerve transection injury
(Elsevier, 2024)
Objective: To test the protective effects of Garcinia kola and curcumin on the ganglion tissues of diabetic rats following the use of autologous vein graft in peripheral nerve transection injury. Methods: The sciatic nerve ...
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
(Springer, 2024)
Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ...