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Toplam kayıt 19, listelenen: 1-10
Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats
(Wolters Kluwer Medknow Publications, 2014)
Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ...
Adalimumab ameliorates abdominal aorta cross clamping which induced liver injury in rats
(Hindawi Ltd, 2014)
The aim of this study was to investigate the possible protective effects of adalimumab (ADA) on cell damage in rat liver tissue during ischemia/reperfusion (I/R) injury of infrarenal abdominal aorta. Thirty male Wistar-albino ...
Infliximab modulates cisplatin-induced hepatotoxicity in rats
(Galenos Publ, 2016)
Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ...
The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats
(Acta Cirurgica Brasileira, 2016)
PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation ...
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
(Verduci Publisher, 2014)
OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ...
Effect of infliximab against cisplatin-induced nephrotoxicity
(Saudi Med J, 2014)
Objectives: To investigate whether infliximab (Ib), an inhibitor of tumor necrosis factor alpha (TNF-alpha), prevents cisplatin (Cis)-induced nephrotoxicity. Methods: the study was performed in the Department of Internal ...
Topiramate has protective effect on renal injury
(Comenius Univ, 2015)
Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ...
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ...
Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period
(Iniestares, S.A., 2015)
OBJECTIVES: Electromagnetic radiation (ER) emitted from cell phones may exert a detrimental influence on human health and may affect the man reproductive system. We aimed to study the biological and morphological effects ...
Effect of infliximab on renal injury due to methotrexate in rat
(Iranian Soc Nephrolgy, 2015)
Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective ...