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Toplam kayıt 19, listelenen: 11-19
Protective effects of infliximab on lung injury induced by methotrexate
(Elsevier Espana Slu, 2015)
Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ...
Protective effect of infliximab against carbon tetrachloride-induced hepatotoxicity
(Begell House Inc, 2015)
Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ...
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
(Wroclaw Medical Univ, 2016)
Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ...
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
(Verduci Publisher, 2016)
OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ...
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
(Mashhad Univ Med Sciences, 2016)
Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ...
High dose zoledronic acid increases ischemia-reperfusion damage of the liver
(Verduci Publisher, 2021)
OBJECTIVE: Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, has been reported to exhibit a protective effect against cancers and prevent bone fractures. It also induces apoptosis by increasing proinflammatory ...
Is adalimumab protective in ischemia‐reperfusion injury in lung?
(Mashhad University of Medical Sciences, 2015)
Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I?R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor?alpha (TNF??) inhibitor agent. We aimed ...
Zoledronic acid aggravates kidney damage during ischemia reperfusion injury in rat
(Begell House Inc., 2015)
Introduction: Zoledronic acid (ZA), a bisphosphonate, increases the levels of cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-?), and reactive oxygen species (ROS) in subjects without cancer. ...
Topiramate reduces aortic cross-clamping-induced lung injury in male rats
(NLM (Medline), 2018)
BACKGROUND: Topiramate (TPM) decreases cytokine release and generation of reactive oxygen species (ROS). Cytokine and endothelin-1 (ET-1) secretion and ROS formation play an important role in ischemia-reperfusion (I/R) ...