Ara
Toplam kayıt 24, listelenen: 11-20
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
(Elsevier, 2022)
Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ...
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
(Verduci Editore, 2022)
OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ...
Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
(Sakarya Üniversitesi, 2021)
Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2)
agonisti ve serotonin reseptör (5-HT2C) antagonisti olan
antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ...
Chronic restraint stress impairs spatial memory while decreasing hippocampal BDNF levels in rats
(İnönü Üniversitesi Tıp Fakültesi, 2022)
Aim: This study investigated the potential role of chronic restraint stress (CRS) on spatial
memory, recognition memory, brain-derived neurotrophic factor (BDNF) and acetylcholine
(ACh) levels in young adult rats.
Material ...
Comparison of linear versus macrocyclic gadolinium chelates in rat skeletal muscle
(2022)
OBJECTIVE: We investigated the effects on skeletal muscle of gadolinium based linear and macrocyclic radiocontrast agents
applied at experimental intervals using histopathological methods.
METHODS: Thirty-two male ...
The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation
(Pergamon-Elsevier Science Ltd, 2020)
Aims: Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately 2.38 million people a year die from respiratory ...
Protective effects of nebivolol on ovarian ischemia-reperfusion injury in rat
(Wiley, 2020)
Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring at rates of 2.7-7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) and histopathological changes in ...
Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus
(Elsevier, 2023)
Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side ef-fects, including cognitive impairment. Agomelatine, a synthetic melatonin analogue, is an important antide-pressant. ...
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
(Verduci Publisher, 2023)
OBJECTIVE: Burns are a global
medical and economic problem. In addition to
high costs, the lengthy therapeutic process and
the emotional trauma experienced by patients
and their families indirectly worsen the socioeconomic ...
The effect of the calcium channel blocker nimodipine on hippocampal BDNF/Ach levels in rats with experimental cognitive impairment
(Taylor & Francis Ltd., 2023)
Objective
Alzheimer’s disease (AD) occurs in approximately 10% to 30% of individuals aged 65 or older worldwide. Novel therapeutic agents therefore need to be discovered in addition to traditional medications. Nimodipine ...