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Toplam kayıt 3, listelenen: 1-3
Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
(Sakarya Üniversitesi, 2021)
Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2)
agonisti ve serotonin reseptör (5-HT2C) antagonisti olan
antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ...
Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus
(Elsevier, 2023)
Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side ef-fects, including cognitive impairment. Agomelatine, a synthetic melatonin analogue, is an important antide-pressant. ...
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)
Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with
proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ...