Ara
Toplam kayıt 15, listelenen: 1-10
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
(Elsevier, 2021)
It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ...
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats
(Taylo & Francis Ltd., 2021)
Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ...
Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress
(Elsevier Ireland Ltd., 2021)
Chronic stress is a potential problem associated with anxiety, depression, and cognitive dysfunction. Bee pollen, a powerful antioxidant, has many therapeutic effects. In this study, we aimed to examine the effects of one ...
Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
(Springer, 2021)
Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ...
The effect of bee pollen on reproductive and biochemical parameters in methotrexate-induced testicular damage in adult rats
(De Gruyter Open Ltd., 2021)
Objectives: Methotrexate (MTX) is an anticancer drug used in chemotherapy. MTX was known for its toxic effects involving most of the organs including testis. Bee pollen is healthy food for human and has antioxidant effect. ...
Geraniolun sıçanlarda anksiyete/depresyon benzeri davranış ve hipokampal kolinerjik sistem üzerine etkileri
(2021)
Amaç: Kronik stresin depresyon benzeri davranışları arttırdığı bilinmektedir. Geraniol nöromodülatör
ve antidepresan etkileri bilinen doğal bir monoterpendir. Bu çalışma, kronik kısıtlama stresi
depresyon modeli sıçanlarda ...
Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
(Sakarya Üniversitesi, 2021)
Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2)
agonisti ve serotonin reseptör (5-HT2C) antagonisti olan
antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ...
Chronic restraint stress impairs spatial memory while decreasing hippocampal BDNF levels in rats
(İnönü Üniversitesi Tıp Fakültesi, 2022)
Aim: This study investigated the potential role of chronic restraint stress (CRS) on spatial
memory, recognition memory, brain-derived neurotrophic factor (BDNF) and acetylcholine
(ACh) levels in young adult rats.
Material ...
Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus
(Elsevier, 2023)
Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side ef-fects, including cognitive impairment. Agomelatine, a synthetic melatonin analogue, is an important antide-pressant. ...
Investigation of symptoms and lung functions in tea packaging factory employees
(Taylor & Francis Ltd., 2023)
Inhalation of organic powders may lead to various diseases such as asthma-like syndrome and hypersensitivity pneumonia. The study aim to evaluate respiratory health effects by respiratory function measurements, respiratory ...