Ara
Toplam kayıt 5, listelenen: 1-5
A promoter polymorphism in the PON1 gene is associated with essential hypertension
(Lippincott Williams & Wilkins, 2015)
Objective:
Increased vascular oxidative stress, the main risk factor of cardiovascular diseases, is seen as a role in the pathophysiology of essential hypertension. Genetic factors also play an important role in the ...
Investigation of the cyp3a4 and pon1 gene variants in turkish patients with familial coronary artery disease
(Lippincott Williams & Wilkins, 2015)
Objective:
Coronary artery disease (CAD), a complex multifactorial disorder, has been suggested to be associated by the interaction of both environmental and genetic risk factors.
The CYP 2C19*2 and CYP2C19*17 polymorphisms play a vital role in platelet responsiveness to clopidogrel after percutaneous coronary intervention: a pharmacogenomic study
(Elsevier, 2015)
Background: Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor. Dual antiplatelet therapy with
clopidogrel and aspirin is recommended treatment by current guidelines for patients ...