Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 558, listelenen: 1-20
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Klinik örneklerden izole edilen karbapenem dirençli pseudomonas aeruginosa izolatlarındaki antibiyotik direncinin moleküler analizi
(2024)Pseudomonas aeruginosa riskli hasta gruplarında morbidite ve mortalitede artışa neden olan fırsatçı patojendir. Karbapenem direncinin tehdit haline geldiği günümüzde, direnç genleri mobil genetik elemanlar aracılığıyla ... -
Investigating the relationship between breast cancer and the postmenopausal period: a systematic meta-analysis
(MRE Press, 2023)One possible explanation for the ongoing debate surrounding breast cancer risk factors is that differences in assessment methodologies lead to conflicting results. One way to address methodological differences in assessment ... -
Dexamethasone and concentrated growth factors on peripheral nerve injury: A clinic-relevant animal study
(Elsevier, 2024)Background: Mandibular nerve injury is a common clinical condition that affects clinicians’ management and patients’ quality of life. In the literature, there are various effective treatments available. The primary purpose ... -
Prognostic importance of PD-L1 expression in bladder cancer patients
(Wolters Kluwer Medknow Publications, 2023)Background: PD-L1/PD-1 molecules are known as important mediators in immune-escape mechanisms of tumors. PD-L1 is highly expressed in various malignancies, including bladder cancer. However, the prognostic value of PD-L1 ... -
Determination of antimicrobial and quorum sensing inhibition potentials of different types of berries from Rize
(Kastamonu University, 2024)Aim of the study: The rapid increase in antibiotic resistance in recent years poses a major threat to public health. Studies indicate that this resistance issue, expressed in alarming numbers, will lead to significant loss ... -
Mortality predictors using chest computed tomography findings in COVID-19 patients
(Gazi University, 2024)Objective: The coronavirus disease (COVID) pandemic is still ongoing. Computed tomography (CT) is widely used in coronavirus disease -2019 (COVID-19) patients for lung damage determination. The aim of this study was to ... -
Investigation of irisin levels in patients with major depressive disorder
(Yerküre Tanıtım & Yayıncılık Hizmetleri, 2024)Objective: Major depressive disorder (MDD) is a common psychiatric disorder. Irisin, produced by proteolysis of FNDC5, is thought to be an exercise -induced hormone that may play a critical role in inducing antidepressant ... -
The relationship between anthropometric and metabolic risk factors and testicular function in healthy young men
(Korean Society for Reproductive Medicine, 2024)Objective: This study investigated the relationship of anthropometric and metabolic risk factors with seminal and sex steroidal hormone parameters in a screened population of healthy males. Methods: The participants were ... -
Metabologenomics and network pharmacology to understand the molecular mechanism of cancer research
(Baishideng Publishing Group Inc. Tutar Y. Metabologenomics and network pharmacology to understand the molecular mechanism of cancer research. World J Clin Cases 2024; 12(3): 474-478 [PMID: 38322468 DOI: 10.12998/wjcc.v12.i3.474], 2024)In this editorial I comment on the article "Network pharmacological and molecular docking study of the effect of Liu-Wei-Bu-Qi capsule on lung cancer" published in the recent issue of the World Journal of Clinical Cases ... -
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
(Springer, 2024)Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ... -
The assessment of neuronal plasticity following sciatic nerve injuries in rats using electron microscopy and stereological methods
(Elsevier, 2024)The transmission of signals to the cell body from injured axons induces significant alterations in primary sensory neurons located in the ganglion tissue, the site of the perikaryon of the affected nerve fibers. Disruption ... -
The effects of Garcinia kola and curcumin on the dorsal root ganglion of the diabetic rat after peripheral nerve transection injury
(Elsevier, 2024)Objective: To test the protective effects of Garcinia kola and curcumin on the ganglion tissues of diabetic rats following the use of autologous vein graft in peripheral nerve transection injury. Methods: The sciatic nerve ... -
The effect of interleukin-20 on periodontal tissue destruction in individuals with periodontitis
(Wiley, 2024)Background and ObjectivePeriodontitis is an inflammatory disease that destroys periodontal tissues. Interleukin-20 (IL-20), on the other hand, is known as a potent angiogenic, chemotactic, and pro-inflammatory cytokine ... -
Long-term protective effects of lamotrigine in a rat ovarian ischemia-reperfusion model
(Elsevier, 2024)Ovarium torsion is a gynecological emergency that is common in women of reproductive age and requires early diagnosis and intervention. In this study, we aimed to investigate the long-term anatomical, histological and ... -
Investigation of the effects of white tea on liver fibrosis: An experimental animal model
(Wiley, 2024)Liver fibrosis is a common, progressive disease that affects millions of patients worldwide. In this study, it was aimed at investigating the effect of white tea on liver fibrosis in an in-vivo environment by creating an ... -
Effects of mineral trioxide aggregate and methyl sulfonyl methane on pulp exposure via RUNX2 and RANKL pathways
(Springer Link, 2024)The aim of this study was to determine the therapeutic effects of mineral trioxide aggregate (MTA) and methyl sulfonyl methane (MSM) on pulp damage due to pulp exposure through the RUNX2 and RANKL pathways. Seventy-two ... -
To determine LDL phenotypes using lipids, lipoproteins, apoproteins, and sdLDL through association rule mining
(Erciyes University Faculty of Medicine, 2023)Objective: The atherogenic lipoprotein phenotype is closely associated with the risk assessment of Coronary Artery Disease (CAD) and the monitoring of treatment processes. Particularly, high levels of small dense low-density ... -
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis
(Wiley, 2024)Objective and Background: Psychological stress is a potential modifiable environmental risk factor causally related to the exacerbation of periodontitis and other chronic inflammatory diseases. This animal study aimed to ... -
The effects of white tea (Camellia Sinensis) and infliximab against cisplatin-induced testicular damage via oxidative stress and apoptosis
(2023)Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, ... -
Inhibition of O6-methylguanine-DNA-methyltransferase (MGMT) by lomeguatrib reduces multiple myeloma cell viability and impairs DNA repair in MGMT-proficient cells
(Wiley, 2024)The function of direct DNA damage repair protein, namely MGMT in MM, and the impact of MGMT on melphalan treatment remains unclear. We showed a significantly higher MGMT mRNA expression in CD138+ myeloma cells than in ...