Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 700, listelenen: 121-140
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Synthesis, characterization, theoretical studies and in vitro embriyotoxic, genotoxic and anticancer effects of novel phenyl(1,4,6-triphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl) methanone
(Taylor & Francis L.T.D., 2023)In this study, phenyl (1,4,6-triphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methanone was obtained by using the Biginelli reaction method. The structure of this compound was analyzed using elemental analysis, IR, 1H, ... -
The potential antioxidant effect of N-acetylcysteine on X-ray ionizing radiation-induced pancreas islet cell toxicity
(Elsevier, 2023)Purpose Previous research has highlighted the impact of X-ray irradiation-induced organ damage, on cancer patients after radiation therapy. The ionizing radiation-induced oxidative stress causes injury to the pancreatic ... -
Analytical investigation of demographic, laboratory, and clinical characteristics of patients with microbial keratitis
(Pamukkale University, 2023)Purpose: In this study, we investigated epidemiological properties, clinical findings, risk factors, direct microscopy, and culture results in patients diagnosed with microbial keratitis. Materials and methods: We examined ... -
Evaluating molecular epidemiology of carbapenem non-susceptible Klebsiella pneumoniae isolates with MLST, MALDI-TOF MS, PFGE
(SpringerNature, 2023)Background This study aimed to evaluate antibiotic resistance genes and virulence genes and the clonal relationship of the carbapenem-nonsusceptible Klebsiella pneumoniae strains by molecular methods which are isolated ... -
The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia
(2023)Abstract. – OBJECTIVE: We aimed to investigate the relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients scheduled for elective transurethral prostate resection surgery ... -
Association between Taql polymorphism of vitamin D receptor gene and vertical growth of the mandible: A cross-sectional study
(2023)Objective: To determine whether the gonial angle on digital panoramic radiographs is associated with vitamin D receptor (VDR) Taql polymorphism. Methods: Genomic DNA samples were collected from the buccal mucosa of patients ... -
The histomorphological and stereological assessment of rat dorsal root ganglion tissues after various types of sciatic nerve injury
(Springer, 2023)Peripheral nerve injuries lead to signifcant changes in the dorsal root ganglia, where the cell bodies of the damaged axons are located. The sensory neurons and the surrounding satellite cells rearrange the composition ... -
Towards a comprehensive tobacco-cessation approach: A pilot-training using simulation based-learning among medical students in Türkiye
(2023)Dear Editor, Tobacco control (TC) is underpinned in two main strategies: preventing youth initiation and promoting tobacco cessation among users1 . Healthcare professionals (HCPs), and specially physicians, should lead ... -
The relationship between laboratory findings and mortality in COVID-19 patients requiring intensive care
(2023)Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows a wide clinical manifestation from asymptomatic infection to life-threatening respiratory failure. This study aimed to determine the ... -
Resveratrol attenuates degeneration and apoptosis of cardiomyocytes induced by aortic clamping
(2023)Introduction: Objective: To investigate the potential beneficial effects of resveratrol (RVT) against ischemia-reperfusion injury of myocardial tissue during surgical treatment of ruptured abdominal aortic aneurysm. Methods: ... -
The effects of dexmedetomidine on trauma-induced secondary injury in rat brain
(Taylor & Francis Ltd., 2023)Background: The objective of this study was to investigate the effect of dexmedetomidine (Dex), a sedative drug with little or no depressant effect on respiratory centers, on secondary injury in rat brain tissue by means ... -
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
Manyetik Rezonans Kontrast Ajanların Sıçan Beyni Üzerine Etkilerinin Histopatolojik Değerlendirilmesi
(2023)Amaç: Gadolinyum tabanlı kontrast ajanlar (GBCA), manyetik rezonans görüntülemelerde (MRG) kontrast sağlamak amaçlı kullanılmaktadır. GBKA yapısına bağlı olarak beyin dokusu ve diğer dokularda birikim olduğu ile ... -
Association and haplotype analysis of the PON1, ITGB3 and CYP3A4 genes, strong candidates for familial coronary artery disease susceptibility
(2023)Objective: Genetic predisposition is very common among the patients with coronary artery disease (CAD), a complex and multifactorial disease. Our objective was to determine the possible association between the most ... -
The effects of topiramate on methotrexate- induced pancreatic injury
(Necmettin Erbakan Üniversitesi, Meram Tıp Fakültes, 2023)Amaç: Bu çalışmada metotreksat ilişkili pankreas hasarında topiramatın pankreasın Langerhans adacık hücreleri üzerine olan etkisinin araştırılması amaçlandı. Gereçler ve Yöntem: Çalışma 04 Temmuz- 24 Temmuz 2022 tarihinde ... -
Eight year evaluation of HIV/tuberculosis co-infection in patients admitted to our hospital
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023)Human immunodeficiency virus (HIV) is a disease that causes serious mortality and morbidity worldwide. Due to the weakening of the immune system, opportunistic infections are common in HIV-positive patients. Tuberculosis, ... -
Investigation of a glioblastoma risk-associated SNP of the PTPRB Gene in familial glioblastoma
(Turkiye Klinikleri, 2023)Objective: To investigate the association of the single nucleotide polymorphism (SNP) rs2252784 in the protein tyrosine phos-phatase receptor type B (PTPRB) gene with familial glioblastoma multiforme (GBM). Material and ... -
Does apoptotic index predict the response to neoadjuvant chemotherapy in patients with breast carcinoma?
(Galenos Publishing, 2023)Objective: Neoadjuvant chemotherapy (NACT) plays a major role in the treatment of patients with locally advanced breast carcinoma. Although most patients have benefited from NACT, the rate of residual tumors is still high ... -
Synthesis and biological evaluation of novel benzylidene thiazolo pyrimidin-3(5H)-one derivatives
(Taylor & Francis Ltd., 2023)Starting compound 1 was synthesized according to reference. 1 Benzylidene thiazole pyrimidin-3(5H)-ones were synthesized reactions of 1 with bromoacetic acid and various aryl-aldehydes in the same vessel via one-step, ... -
Seroprevalence of toxoplasma, rubella and cytomegalovirus in women of fertility age in our region
(Galenos Publishing, 2023)Objective: Toxoplasma gondii (T. gondii), Rubella and Cytomegalovirus (CMV) infections can cause severe morbidity in the fetus when transmissed during pregnancy. In our study, it was aimed to examine the seropositivity ...
