Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 717, listelenen: 201-220
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Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
(Sakarya Üniversitesi, 2021)Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2) agonisti ve serotonin reseptör (5-HT2C) antagonisti olan antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ... -
The relationship of serum asymmetric dimethylarginine concentrations and lung involvement in patients with COVID-19 infection
(2021)Aim: COVID-19 infections the tissue through angiotensin converting enzyme 2 receptor, which is also expressed on endothelial cells. Endothelial dysfunction may be associated with lung involvement. Asymmetric dimethylarginine ... -
Comparison of DNA isolation methods from mammalian sperm cells and development of a new protocol
(Effect Publishing Agency ( EPA ), 2021)Sperm DNA tightly packed with protamines makes the DNA isolation procedure from sperm cells long and laborious. Cell lysis is also a challenging step because of the disulfide bonds-rich membranes of the sperm cells. In ... -
Covid-19 hastalarında kardiyak troponin-ı’nın cinsiyet ilişkili prognostik değeri
(Kırıkkale Üniversitesi, 2021)Amaç: Kardiyak troponinler kardiyak ve non-kardiak birçok hastalıkta yükselebilmektedir. Çalışmamızda COVID-19 hastalarının hastaneye kabulünde kardiyak troponin-I seviyesinin yoğun bakım ihtiyacı ve tüm nedenlere ... -
Çeşitli klinik örneklerden izole edilen gram negatif gsbl pozitif bakterilerin antibiyotiklere direnç oranları
(DNT Ortadoğu Yayıncılık A.Ş., 2021)Amaç: Genişlemiş Spektrumlu Beta Laktamaz (GSBL) pozitif mikroorganizmaların neden olduğu enfeksiyonların tedavisindeki zorluklar günümüzde en önemli sağlık sorunlarından biridir. çeşitli bakteriyolojik kültürlerinden ... -
Geraniolun sıçanlarda anksiyete/depresyon benzeri davranış ve hipokampal kolinerjik sistem üzerine etkileri
(2021)Amaç: Kronik stresin depresyon benzeri davranışları arttırdığı bilinmektedir. Geraniol nöromodülatör ve antidepresan etkileri bilinen doğal bir monoterpendir. Bu çalışma, kronik kısıtlama stresi depresyon modeli sıçanlarda ... -
The effects of dexmedetomidine against ruptured abdominal aortic aneurysm injury to myocardial tissue induced by abdominal aorta clamping
(Effect Publishing Agency ( EPA ), 2021)Objectives: This study aims to examine the potential protective effect of the selective alpha-2 adrenergic receptor agonist dexmedetomidine (DEX) against aortic occlusion-induced myocardial injury. Patients and methods: ... -
Comparison of Er:YAG modalities (PIPS-SWEEPS) onEliminating of enterococcus faecalis populations
(Selçuk Üniversitesi Dişhekimliği Fakültesi, 2021)Comparison of Er:YAG Modalities (PIPS-SWEEPS) on Eliminating of Enterococcus Faecalis Populations Background: To determine the effectiveness of novel two Er:YAG lasers modalities, photon-initiated photoacoustic ... -
Yoğun bakım ünitelerinde izole edilen candida türleri ve antifungal duyarlılıkları: Üç yıllık çalışma
(2021)Amaç: Candida, yoğun bakım hastalarında yüksek mortalite ile sonuçlanan ciddi enfeksiyonlara neden olur. Bu retrospektif çalışmada çeşitli klinik örneklerinden Candida suşları izole edilmiş yoğun bakım hastalarına ait ... -
Çeşitli klinik örneklerden izole edilen stenotrophomonasmaltophilia suşlarının dağılımı ve antimikrobiyal duyarlılıkları: 8 yıllık çalışma
(2021)Amaç: Hastane enfeksiyonları ve buna bağlı mortalitenin artması çoklu ilaç direncine sahip fırsatçı patojenleri her zamankinden daha fazla gündeme getirmiştir. Bunlar arasında yer alan stenotrophomonas maltophilia önemi ... -
Effectiveness of laboratory parameters as morbidity and mortality indicators in patients with coronavirus disease-2019 admitted to the intensive care unit
(2021)Objective: Laboratory parameters may predict the severity and mortality of coronavirus disease-2019 (COVID-19). We investigated the relationship of laboratory findings obtained at admission and 72nd hour and mortality and ... -
GLUT-1 expression in breast cancer
(Federation of Turkish Pathology Societies, 2022)Objective: Numerous studies have been conducted to predict the prognosis of breast cancers. The effect of glucose transporter protein 1 (GLUT-1), the main carrier protein responsible for glucose transport, was investigated ... -
Histopathological evaluation of the effects of dexmedetomidine against pituitary damage ınduced by X-ray irradiation
(Taylor & Francis Ltd., 2022)Background: The present study, aimed to investigate the potential negative effects of x-ray radiation and the effects of the α2-adrenergic receptor agonist dexmedetomidine on the pituitary gland. Methods: Twenty-four ... -
Association of serum interleukin-17 and Interleukin-23 levels with disease activity, function, mobility, enthesitis index in patients with ankylosing spondylitis
(Georg Thieme Verlag, 2022)Aim: More and more studies have demonstrated that the interleukin (IL)-23/IL-17 axis is highly associated with immune dysfunction and activated autoimmune inflammation. The purposes of this study were to determine the serum ... -
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
(Verduci Editore, 2022)OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ... -
Evaluation of thiol-disulfide homeostasis in active ankylosing spondylitis patients
(Ediciones Doyma, S.L., 2021)Introduction and objectives: The etiopathogenesis of ankylosing spondylitis (AS), which is a chronic, progressive, inflammatory, systemic disease, has not been fully elucidated yet. Thiol-disulfide homeostasis, a component ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
(Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
The effect of usnea longissima extract on lung cancer cell line (A549)
(2021)Objective: Some lichens are known to demonstrate anticancer activity. However, to the best of our knowledge, no information is available about the activity of Usnea longissima against human lung cancer A549 cells. This ... -
What does the procalcitonin level tell us in patients with acute pancreatitis?
(College of Physicians and Surgeons Pakistan, 2022)Objective: To determine the factors affecting the procalcitonin level, and its association with the severity of pancreatitis in patients with acute pancreatitis (AP). Study Design: Cross-sectional analytical study. Place ... -
Hiv seropositivity in patients admitted to our hospital: Six year evaluation
(Duzce University, 2021)Aim: Detecting human immunodeficiency virus (HIV)-infected individuals is very important in terms of quality of patients’ lives. However, it should be kept in mind that there may be false positives and tests must be ...
