Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 587, listelenen: 41-60
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Association between Taql polymorphism of vitamin D receptor gene and vertical growth of the mandible: A cross-sectional study
(2023)Objective: To determine whether the gonial angle on digital panoramic radiographs is associated with vitamin D receptor (VDR) Taql polymorphism. Methods: Genomic DNA samples were collected from the buccal mucosa of patients ... -
The histomorphological and stereological assessment of rat dorsal root ganglion tissues after various types of sciatic nerve injury
(Springer, 2023)Peripheral nerve injuries lead to signifcant changes in the dorsal root ganglia, where the cell bodies of the damaged axons are located. The sensory neurons and the surrounding satellite cells rearrange the composition ... -
Towards a comprehensive tobacco-cessation approach: A pilot-training using simulation based-learning among medical students in Türkiye
(2023)Dear Editor, Tobacco control (TC) is underpinned in two main strategies: preventing youth initiation and promoting tobacco cessation among users1 . Healthcare professionals (HCPs), and specially physicians, should lead ... -
The relationship between laboratory findings and mortality in COVID-19 patients requiring intensive care
(2023)Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows a wide clinical manifestation from asymptomatic infection to life-threatening respiratory failure. This study aimed to determine the ... -
Resveratrol attenuates degeneration and apoptosis of cardiomyocytes induced by aortic clamping
(2023)Introduction: Objective: To investigate the potential beneficial effects of resveratrol (RVT) against ischemia-reperfusion injury of myocardial tissue during surgical treatment of ruptured abdominal aortic aneurysm. Methods: ... -
The effects of dexmedetomidine on trauma-induced secondary injury in rat brain
(Taylor & Francis Ltd., 2023)Background: The objective of this study was to investigate the effect of dexmedetomidine (Dex), a sedative drug with little or no depressant effect on respiratory centers, on secondary injury in rat brain tissue by means ... -
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
Manyetik Rezonans Kontrast Ajanların Sıçan Beyni Üzerine Etkilerinin Histopatolojik Değerlendirilmesi
(2023)Amaç: Gadolinyum tabanlı kontrast ajanlar (GBCA), manyetik rezonans görüntülemelerde (MRG) kontrast sağlamak amaçlı kullanılmaktadır. GBKA yapısına bağlı olarak beyin dokusu ve diğer dokularda birikim olduğu ile ... -
Association and haplotype analysis of the PON1, ITGB3 and CYP3A4 genes, strong candidates for familial coronary artery disease susceptibility
(2023)Objective: Genetic predisposition is very common among the patients with coronary artery disease (CAD), a complex and multifactorial disease. Our objective was to determine the possible association between the most ... -
The effects of topiramate on methotrexate- induced pancreatic injury
(Necmettin Erbakan Üniversitesi, Meram Tıp Fakültes, 2023)Amaç: Bu çalışmada metotreksat ilişkili pankreas hasarında topiramatın pankreasın Langerhans adacık hücreleri üzerine olan etkisinin araştırılması amaçlandı. Gereçler ve Yöntem: Çalışma 04 Temmuz- 24 Temmuz 2022 tarihinde ... -
Eight year evaluation of HIV/tuberculosis co-infection in patients admitted to our hospital
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023)Human immunodeficiency virus (HIV) is a disease that causes serious mortality and morbidity worldwide. Due to the weakening of the immune system, opportunistic infections are common in HIV-positive patients. Tuberculosis, ... -
Investigation of a glioblastoma risk-associated SNP of the PTPRB Gene in familial glioblastoma
(Turkiye Klinikleri, 2023)Objective: To investigate the association of the single nucleotide polymorphism (SNP) rs2252784 in the protein tyrosine phos-phatase receptor type B (PTPRB) gene with familial glioblastoma multiforme (GBM). Material and ... -
Does apoptotic index predict the response to neoadjuvant chemotherapy in patients with breast carcinoma?
(Galenos Publishing, 2023)Objective: Neoadjuvant chemotherapy (NACT) plays a major role in the treatment of patients with locally advanced breast carcinoma. Although most patients have benefited from NACT, the rate of residual tumors is still high ... -
Synthesis and biological evaluation of novel benzylidene thiazolo pyrimidin-3(5H)-one derivatives
(Taylor & Francis Ltd., 2023)Starting compound 1 was synthesized according to reference. 1 Benzylidene thiazole pyrimidin-3(5H)-ones were synthesized reactions of 1 with bromoacetic acid and various aryl-aldehydes in the same vessel via one-step, ... -
Seroprevalence of toxoplasma, rubella and cytomegalovirus in women of fertility age in our region
(Galenos Publishing, 2023)Objective: Toxoplasma gondii (T. gondii), Rubella and Cytomegalovirus (CMV) infections can cause severe morbidity in the fetus when transmissed during pregnancy. In our study, it was aimed to examine the seropositivity ... -
Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome
(Springer, 2023)Purpose: To evaluate serum semaphorin 3A (Sema3A) and interleukin 6 (IL-6) levels in pseudoexfoliation syndrome (PXS) patients to determine whether these mediators play a role in the systemic manifestations of PXS. Methods: ... -
Diagnostic value of serum signal peptide-CUB-EGF-like domain- containing protein 1 levels in patients with acute appendicitis
(Assoc Medica Brasileira, 2023)OBJECTIVE: Acute appendicitis is one of the most common surgical causes of an acute abdomen among patients admitted to the emergency room due to abdominal pain. The clinical diagnosis of acute appendicitis is usually ... -
The effects of coenzyme Q10 (CoQ10) on Ionizing radiation- induced pancreatic β-cell injury
(AVES, 2023)Objective: This study investigated the antioxidant effect of coenzyme Q10 on ionizing radiation induced oxidative damage in pancreatic & beta;-cells. Methods: Twenty-four male rats were assigned to 4 groups. Group 1 ... -
Protective effect of vaccinium myrtillus extract on x-ray irradiation-induced retinal toxicity via enos and 8-ohdgexpression
(Karger, 2023)Every year, hundreds of thousands of cancer patients receive radiotherapy treatment. Oxidative stress is observed in healthy tissues due to irradiation exposure. The present study is the first to address the effects of ... -
The effects of carvacrol on transient receptor potential (TRP) channels in an animal model of parkinson's disease
(Springer, 2023)In this study, we aimed to investigate the effects of carvacrol (CA), a widely used phytochemical having anti-oxidant and neuroprotective effects, on transient receptor potential (TRP) channels in an animal model of ...