Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 700, listelenen: 481-500
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Fibroblast growth factor 21 and its relation to metabolic parameters in women with polycystic ovary syndrome
(Taylor & Francis Ltd, 2014)Objective. the aim of this study was to compare the serum levels of fibroblast growth factor 21 (FGF-21) between patients with polycystic ovary syndrome (PCOS) and control subjects and to assess the possible relation with ... -
Comparison of standard triple therapy, sequential therapy and moxifloxacin-based triple therapy for Helicobacter pylori infection: Patients' compliance and bacterial eradication rates
(Wiley, 2014)ObjectiveTo compare the patients' compliance with and the efficacy of existing treatments for Helicobacter pylori eradication, including moxifloxacin-based triple therapy, sequential treatment and the standard treatment. ... -
Effect of infliximab against cisplatin-induced nephrotoxicity
(Saudi Med J, 2014)Objectives: To investigate whether infliximab (Ib), an inhibitor of tumor necrosis factor alpha (TNF-alpha), prevents cisplatin (Cis)-induced nephrotoxicity. Methods: the study was performed in the Department of Internal ... -
Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats
(Wolters Kluwer Medknow Publications, 2014)Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ... -
In vitro study of human lymphocytes cytological and biochemical effects by zingiberene
(Taylor & Francis Inc, 2014)In this study, the cytological and biochemical effects of zingiberene (ZBN) on human lymphocytes cultures were investigated. the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and lactate dehydrogenase ... -
Analysis of cytokine gene polymorphism allelic variation in the Turkish population with inflammatory bowel disease
(Allied Acad, 2014)Inflammatory bowel diseases (IBD), Crohn's Disease (CD) and Ulcerative Colitis (UC) are complex diseases showing genetic heterogeneity that arise with the interaction of the genetic and environmental agents. the prevalence ... -
Determination of a novel integron-located variant (bla(OXA-320)) of class D beta-lactamase in Proteus mirabilis
(Wiley, 2014)Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. the isolate was identified ... -
MIF/CD74 guided therapeutic strategy for relapsed glioblastoma patients
(Amer Assoc Cancer Research, 2014)Abstract Introduction: No universally effective systemic treatments are available for patients whose malignant brain tumor recurs after primary treatment. The treatment for Glioblastoma (GBM) patients consists of surgical ... -
Hepcidin expression in psoriasis patients
(Medknow Publications & Media Pvt Ltd, 2014)Background: Iron is an essential nutrient for mammals. Accelerated loss of nutrients through hyperproliferation and desquamation from the skin in psoriasis is known. Hepcidin is an important and recently discovered regulator ... -
Syringaldehyde exerts neuroprotective effect on cerebral ischemia injury in rats through anti-oxidative and anti-apoptotic properties
(Shenyang Editorial Dept Neural Regeneration Res, 2014)There are few studies on the neuroprotective effects of syringaldehyde in a rat model of cerebral ischemia. the study aimed to elucidate the mechanisms underlying the neuroprotective effects of syringaldehyde on ischemic ... -
Anatomic variations of sphenoid sinus pneumatization in a sample of Turkish Population: MRI study
(Soc Chilena Anatomia, 2014)There are a number of variations regarding morphometric anatomy and degree of pneumatization of the sphenoid sinus. in our study, we planned to examine and show the differences of pneumatization of the sphenoid sinus ... -
Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer
(Int Inst Anticancer Research, 2015)Background/Aim: Oxidative stress plays a role on the development of colorectal cancer. Manganese superoxide disnzutase (MnSOD) and glutathione peroxidase I (GPXI) are crucial in regulating oxidative balance and its ... -
Clinical significance of neutrophil gelatinase-associated lipocalin in crimean-congo hemorrhagic fever
(Hindawi Ltd, 2015)Neutrophil gelatinase-associated lipocalin (NGAL), which is an important prognostic marker for sepsis and inflammatory diseases, is mostly released from neutrophils. Crimean-Congo hemorrhagic fever (CCHF) patients are ... -
Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?
(Elsevier Science Bv, 2015)Objective: Resveratrol, a phytoalexin polyphenol, has anti-angiogenic, antioxidant, anti-inflammatory properties. We aimed to compare the anti-inflammatory and anti-angiogenic effects of resveratrol and leuprolide acetate ... -
In vitro cytotoxic, genotoxic and antioxidant/oxidant effects of guaiazulene on human lymphocytes
(Inst Tecnologia Parana, 2015)The aim of this study was to evaluate for the cytotoxicity, genotoxicity and antioxidant/oxidant activity of GYZ on human peripheral blood lymphocytes (PBLs). Guaiazulene (GYZ) was added into culture tubes at various ... -
Wernicke's encephalopathy in a patient with unresectable gastric carcinoma and literature review
(E-Century Publishing Corp, 2015)Wernicke's encephalopathy (WE) is a disease classically associated with nutrition deficiency. It is characterized by typical symptoms like confusion, ataxia and ophthalmoparesis, and developes due to thiamine deficieny in ... -
Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats
(Shenyang Editorial Dept Neural Regeneration Res, 2015)Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally ... -
Soluble urokinase-type plasminogen activator receptor is a novel biomarker predicting acute exacerbation in COPD
(Dove Medical Press Ltd, 2015)Background: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition, and progresses with acute exacerbations. (AE). During AE, levels of acute phase reactants such as C-reactive protein (CRP) and ... -
Topiramate has protective effect on renal injury
(Comenius Univ, 2015)Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ... -
Copeptin: a new predictor for severe obstructive sleep apnea
(Dove Medical Press Ltd, 2015)Introduction: Copeptin which is the C-terminal fragment of antidiuretic hormone (ADH), is a biomarker that has been reported to be increased in various cardiovascular disorders, cerebrovascular diseases and associated with ...