Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 717, listelenen: 81-100
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Pandemic process in children
(İnönü Üniversitesi Tıp Fakültesi, 2023)Aim: When compared to adults, it is seen that the COVID-19 disease in children has a milder course. However, considering that there are cases with severe course and even death, it is aimed to analyze the COVID-19 PCR ... -
Factors affecting mortality in COVID-19 patients treated with intravenous immunoglobulin
(İnönü Üniversitesi Tıp Fakültesi, 2023)Aim: Intravenous immunoglobulin (IVIG), used as an option in the treatment of severe Coronavirus disease 2019 (COVID-19), has been shown to have effects on the suppression of the hyperinflammatory state through immunomodulatory ... -
FOBTs with lower detection limits increase the colonoscopy rates
(Türk Klinik Biyokimya Derneği, 2023)Aim: Colon cancer, accounting for almost 10% of all cancers in both genders worldwide, is the fourth most common cause of cancer-related deaths. Approximately 95% of cases are originated from adenomas. In recent years, ... -
Cellular immunity in individuals classified by antibody, after covid-19 infection/vaccine
(Türk Klinik Biyokimya Derneği, 2023)Aim: Regarding coronavirus disease (COVID-19), despite antibody measurement alone providing insufficient data, studies evaluating immune responses to vaccination or disease have focused on humoral immunity. Uncoupled humoral ... -
Tumor-infiltrating lymphocytes may predict prognosis in breast cancer patients receiving neoadjuvant chemotherapy
(2023)Objective: Investigation of the histopathological features in core biopsies can predict the chemotherapy responses and thus provide information about the prognosis of breast cancer patients. Tumor-infiltrating lymphocytes ... -
Targeting ITGβ3 to overcome trastuzumab resistance through epithelial–mesenchymal transition regulation in HER2-positive breast cancer
(MDPI, 2024)HER2-positive breast cancer, representing 15–20% of all breast cancer cases, often develops resistance to the HER2-targeted therapy trastuzumab. Unfortunately, effective treatments for advanced HER2-positive breast cancer ... -
Colorimetric and fluorimetric sensing of trace amount of Hg2+in real samples by a new rhodamine B-based Schiff base probe: Smartphone, living cell applications and DFT calculation
(Elsevier, 2024)In this study, a Schiff base-based probe, named as 2-((methyl benzoate-4-yl)methyleneamino)-3 ',6 '-bis(diethylamino)spiro[isoindoline-1,9 '-xanthene]-3-one (2), was successfully synthesized and characterized by various ... -
PAI1 regulates cell morphology and migration markers in trastuzumab-resistant HER2-positive breast cancer cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)HER2-positive breast cancer is a significant cause of mortality. Overcoming trastuzumab resistance requires a deeper understanding of its molecular mechanisms to develop effective therapies. This study investigates the ... -
Chitosan-coated scorpion venom ameliorates acute lung injury caused by klebsiella pneumoniae
(Springer, 2024)Nosocomial infections caused by antibiotic-resistant bacteria result in significant economic costs and human health issues, including acute lung injury. The purpose of this study was to investigate the scorpion venom in ... -
Synthetic and non-synthetic inhibition of ADAM10 and ADAM17 reduces inflammation and oxidative stress in LPS-induced acute kidney injury in male and female mice
(Elsevier, 2024)Acute kidney injury (AKI) is a severe medical condition that can lead to illness and death. A disintegrin and metalloprotease (ADAM) protein family is a potential treatment target for AKI due to its involvement in inflammation, ... -
Factors affecting mortality in COVID-19 patients treated with tocilizumab
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024)The aim of our study was to evaluate the risk factors associated with mortality in COVID-19 patients. During March 2020 to March 2022, 136 patients who were treated with tocilizumab in the service and intensive care unit ... -
The role of platelet to lymphocyte ratio (plr) in predicting early treatment response in diffuse large b cell lymphoma
(Springer, 2024)Background: Systemic inflammatory response in diffuse large B-cell lymphoma (DLBCL) is closely related to disease prognosis. Our aim is to determine the role of pretreatment platelet-to-lymphocyte ratio (PLR) in predicting ... -
Immune system dysregulation in the pathogenesis of non-alcoholic steatohepatitis: unveiling the critical role of T and B lymphocytes
(Frontiers Media SA, 2024)Non-alcoholic fatty liver disease (NAFLD), characterized by the excessive accumulation of fat within the cytoplasm of hepatocytes (exceeding 5% of liver weight) in individuals without significant alcohol consumption, has ... -
Stereology of the dorsal root ganglion in peripheral nerve studies
(Nova Science Publishers, Inc., 2024)Qualitative histopathology has long been the gold standard for evaluating morphological tissue changes in all organ systems, including the peripheral and central nervous systems. However, it is not fully capable of ... -
Evaluation of choroidal thickness and retinal vessel density with serum HIF-1α and TNF-α level in patients with OSAS
(Taylor & Francis Ltd., 2024)Purpose: To reveal changes in choroidal thickness, retinal vessel density, and serum HIF-1α and TNF-α levels in obstructive sleep apnea syndrome (OSAS) and their correlation. Methods: This prospective case-control study ... -
Factors affecting mortality at home and hospital in oncology patients and the effect of age
(Turkiye Klinikleri, 2024)Objective: Several factors assessing cancer mortality and impacting the choice of place of death for terminally ill patients have been previously documented. We examined the relationships between several oncological factors, ... -
Relationship between breast cancer and cardiac myxoma
(Tehran University of Medical Sciences, 2024)... -
Production of platelet-rich plasma (PRP)-enriched scaffolds for bone tissue regeneration with 3D printing technology
(Elsevier, 2024)Bone disorders signify diverse abnormalities in the structure, development, and functions of bone tissue in the human body, with a significant correlation to ageing, insufficient physical activity, and escalating obesity. ... -
The effects of mineral trioxide aggregate and second-generation autologous growth factor on pulpotomy via TNF-α and NF-kβ/p65 pathways
(Springer, 2024)This study aims to investigate the effect of Mineral Trioxide Aggregate (MTA), a bioactive endodontic cement, and Concentrated Growth Factor (CGF), a second-generation autologous growth factor, on pulpotomy-induced pulp ... -
Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats
(Springer, 2024)Scalding burns are a common form of thermal injury that often leads to systemic complications. Pro-inflammatory cytokines like interleukin-6 (IL-6) and the activation of signal transducer and activator of transcription 3 ...
