Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 700, listelenen: 81-100
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Production of platelet-rich plasma (PRP)-enriched scaffolds for bone tissue regeneration with 3D printing technology
(Elsevier, 2024)Bone disorders signify diverse abnormalities in the structure, development, and functions of bone tissue in the human body, with a significant correlation to ageing, insufficient physical activity, and escalating obesity. ... -
The effects of mineral trioxide aggregate and second-generation autologous growth factor on pulpotomy via TNF-α and NF-kβ/p65 pathways
(Springer, 2024)This study aims to investigate the effect of Mineral Trioxide Aggregate (MTA), a bioactive endodontic cement, and Concentrated Growth Factor (CGF), a second-generation autologous growth factor, on pulpotomy-induced pulp ... -
Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats
(Springer, 2024)Scalding burns are a common form of thermal injury that often leads to systemic complications. Pro-inflammatory cytokines like interleukin-6 (IL-6) and the activation of signal transducer and activator of transcription 3 ... -
Non-genetic heterogeneity and immune subtyping in breast cancer: Implications for immunotherapy and targeted therapeutics
(Elsevier, 2024)Breast cancer (BC) is a complex and multifactorial disease, driven by genetic alterations that promote tumor growth and progression. However, recent research has highlighted the importance of non-genetic factors in shaping ... -
Electrophysiological and histopathological evaluation of the effectiveness of melatonin and glatiramer acetate for traumatic facial nerve injuries
(Elsevier, 2024)Aim: This study aimed to evaluate the effect of systemic/local use of melatonin and glatiramer acetate on regeneration in traumatic nerve injury models. Materials and methods: A total of 42 male Wistar albino rats were ... -
Prognostic significance of C-reactive protein/albumin and neutrophil/lymphocyte ratios in patients with COVID-19
(Publishing Office of the University of Rzeszow, 2024)Introduction and aim. COVID-19 causes an uncontrolled and generalized inflammatory response of the host immune system. Early recognition of the disease and early prediction of the clinical course are of great importance. ... -
An electrochemical immuno-cytosensor modified with nanofibers for the determination of a carcinoembryonic antigen
(Springer, 2024)In this study, La0.25Fe0.75FeO3 (PNp)perovskite nanoparticle was synthesized using the sol–gel method. PNp-coated polyacrylonitrile (PAN) nanofibers were prepared by electrospinning on the pencil graphite electrode (PGE) ... -
Integrin β3 reprogramming stemness in HER2-positive breast cancer cell lines
(MDPI, 2024)HER2-positive breast cancer, characterised by overexpressed HER2 levels, is associated with aggressive tumour behaviour and poor prognosis. Trastuzumab is a standard treatment; however, approximately 50% of patients develop ... -
Does genetic variation in PNPLA3, TM6SF2 and HSD17B13 have a role in the development or prognosis of hepatocellular carcinoma in Turkish patients with Hepatitis B?
(2024)BACKGROUND AND AIMS: Progression to hepatocellular carcinoma (HCC) is restricted by viral suppression in chronic hepatitis B (CHB); however, some patients still progress despite antiviral therapy. Presence of single ... -
Propolis reduces inflammation and dyslipidemia caused by high-cholesterol diet in mice by lowering ADAM10/17 activities
(MDPI, 2024)Atherosclerosis is one of the most important causes of cardiovascular diseases. A disintegrin and metalloprotease (ADAM)10 and ADAM17 have been identified as important regulators of inflammation in recent years. Our study ... -
The effect of 3D modeling on family quality of life, surgical success, and patient outcomes in congenital heart diseases: objectives and design of a randomized controlled trial
(2024)Background: Understanding the severity of the disease from the parents' perspective can lead to better patient outcomes, improving both the child's health-related quality of life and the family's quality of life. The ... -
The relationship between SYNTAX II score and serum pleiotrophin level in patients with non-ST-segment elevation myocardial infarction
(Galenos Publishing House, 2024)Background and Aim: In this study, we aimed to examine the relationship between serum pleiotrophin (PTH) levels at admission and the severity of coronary artery disease (CAD) in patients experiencing non-ST-segment elevation ... -
Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents
(BioMed Central Ltd., 2024)Background: Carbazole-based molecules containing thiosemicarbazide functional groups are recognized for their diverse biological activities, particularly in enhancing therapeutic anticancer effects through inhibiting crucial ... -
Did diet compliance and remission reduce oxidative stress in celiac patients?
(Associacao Medica Brasileira, 2024)OBJECTIVE: We aimed to examine the effect of remission status on thiol–disulfide homeostasis in celiac patients and thus to indirectly determine the effect of oxidative stress and inflammation caused by non-compliance with ... -
Comparative analysis of epigallocatechin-3-gallate and TNF-alpha inhibitors in mitigating cisplatin-induced pancreatic damage through oxidative stress and apoptosis pathways
(Springer, 2024)Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as cancer cells. In this study, we aimed to investigate the effect of ... -
Evaluation of the protective effect of coenzyme Q10 against x-ray irradiation-induced ovarian injury
(Wiley, 2024)Aim: This study focused on the anti-oxidant and anti-apoptotic effects of CoQ10 in ovaries exposed to pelvic radiation. Methods: Thirty-two female rats were randomly assigned into four groups. Group I (control group), Group ... -
Klinik örneklerden izole edilen karbapenem dirençli pseudomonas aeruginosa izolatlarındaki antibiyotik direncinin moleküler analizi
(2024)Pseudomonas aeruginosa riskli hasta gruplarında morbidite ve mortalitede artışa neden olan fırsatçı patojendir. Karbapenem direncinin tehdit haline geldiği günümüzde, direnç genleri mobil genetik elemanlar aracılığıyla ... -
Investigating the relationship between breast cancer and the postmenopausal period: a systematic meta-analysis
(MRE Press, 2023)One possible explanation for the ongoing debate surrounding breast cancer risk factors is that differences in assessment methodologies lead to conflicting results. One way to address methodological differences in assessment ... -
Dexamethasone and concentrated growth factors on peripheral nerve injury: A clinic-relevant animal study
(Elsevier, 2024)Background: Mandibular nerve injury is a common clinical condition that affects clinicians’ management and patients’ quality of life. In the literature, there are various effective treatments available. The primary purpose ... -
Prognostic importance of PD-L1 expression in bladder cancer patients
(Wolters Kluwer Medknow Publications, 2023)Background: PD-L1/PD-1 molecules are known as important mediators in immune-escape mechanisms of tumors. PD-L1 is highly expressed in various malignancies, including bladder cancer. However, the prognostic value of PD-L1 ...
