Novel phthalocyanines bearing 1,2,4 triazole substituents: Synthesis, characterization, photophysical and photochemical properties
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CitationDemirbaş, Ü., Özçiftçi, Z., Akçay, H.T. & Menteşe, E. (2020). Novel phthalocyanines bearing 1,2,4 triazole substituents: Synthesis, characterization, photophysical and photochemical properties. Polyhedron, 181, 114470. https://doi.org/10.1016/j.poly.2020.114470
4-(4,5-Diphenyl-4H-1,2,4-triazol-3-ylthio)phthalonitrile ( 3) and its non-peripherally tetra substituted zinc(II) phthalocyanine (4) and magnesium(II) phthalocyanine (5) derivatives were prepared. the novel compounds 3-5 were characterized spectroscopically. To determine the photodynamic therapy potential of 4 and 5, their photophysical and photochemical properties were investigated. the magnesium(II) phthalocyanine (5) showed the highest fluorescence quantum yield. in addition, non-peripheral substitution of the 4-(4,5-diphenyl-4H-1,2,4-triazol-3-ylthio) groups on the phthalocyanine ring did not affect the fluorescence properties of the phthalocyanines. the zinc(II) phthalocyanine (4) exhibited the highest singlet oxygen quantum yield value. the 4 and 5 exhibited lower photostability than Std-ZnPc. These results show that the zinc(II) phthalocyanine (4) can be used in photodynamic therapy applications with its singlet oxygen production and photostability. (C) 2020 Elsevier Ltd. All rights reserved.