Yazar "RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" için TR-Dizin İndeksli Yayınlar Koleksiyonu listeleme
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The effects of royal jelly on the oxidantantioxidant system in rats with N-methyl- N-nitrosourea-induced breast cancer
Malkoç, Meltem; Altay, Diler Us; Alver, Ahmet; Ersöz, Şafak; Şen, Tuğba Mazlum; Kural, Birgül Vanizor; Uydu, Hüseyin Avni (2018)Objectives: To determine the effect of royal jelly (RJ) on the oxidant-antioxidant balance in rats with N-methyl-Nnitrosourea (MNU) induced breast cancer and to compare this with the chemotherapeutic agent paclitaxel. ... -
Eight year evaluation of HIV/tuberculosis co-infection in patients admitted to our hospital
Bahçeci, İlkay; Alpdoğan, Yunus Emre; Duran, Ömer Faruk; İbik, Yunus Emre; Arslan, Nuray; Şahin, Kazım (Yuzuncu Yil Universitesi Tip Fakultesi, 2023)Human immunodeficiency virus (HIV) is a disease that causes serious mortality and morbidity worldwide. Due to the weakening of the immune system, opportunistic infections are common in HIV-positive patients. Tuberculosis, ... -
Geraniolun sıçanlarda anksiyete/depresyon benzeri davranış ve hipokampal kolinerjik sistem üzerine etkileri
Amaç: Kronik stresin depresyon benzeri davranışları arttırdığı bilinmektedir. Geraniol nöromodülatör ve antidepresan etkileri bilinen doğal bir monoterpendir. Bu çalışma, kronik kısıtlama stresi depresyon modeli sıçanlarda ... -
Hiv seropositivity in patients admitted to our hospital: Six year evaluation
Bahçeci, İlkay; Yıldız, İlknur Esen (Duzce University, 2021)Aim: Detecting human immunodeficiency virus (HIV)-infected individuals is very important in terms of quality of patients’ lives. However, it should be kept in mind that there may be false positives and tests must be ... -
How to decrease the rejection rates: reasons of sample rejection and solutions
Çelik, Saadet; Seyrekel, Tuncay; Arpa, Medeni (Walter de Gruyter GMBH, 2018)Objective: Sample rejection is an important step in the laboratory related with the patient safety. Periodical analysis of rejected samples is necessary to define the causes of rejection and follow-up the requirements for ... -
In vitro activity of ceftaroline to MRSA isolates: a multicenter study
Mengeloğlu, Fırat Zafer; Taş, Tekin; Koçoğlu, Esra; Çopur Çiçek, Aysegül; Yanık, Keramettin; Güneş, Hayati; Çiftçi, İhsan Hakkı; Durmaz, Süleyman; Bucak, Özlem; Güçkan, Rıdvan; Terzi, Hüseyin Agah; Yavuz, Muhsine Zeynep (Ankara Microbiology Soc, 2013)Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging pathogen that cause severe community- and hospital-acquired infections. Studies continue on searching alternatives due to the limited number of therapeutic ... -
In vitro cytotoxic, genotoxic, and oxidative effects of acyclic sesquiterpene farnesene
Farnesene (FNS) is an acyclic sesquiterpene. It has a wide range of important biological effects such as antioxidant, antimicrobial, and antifungal properties, although its cytotoxic, cytogenetic, and oxidative effects ... -
Infliximab modulates cisplatin-induced hepatotoxicity in rats
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Kırbaş, Aynur; Tümkaya, Levent; Yılmaz, Arif; Türkyılmaz, Ayşegül Küçükali; Sehitoğlu, İbrahim; Yüce, Süleyman (Galenos Publ, 2016)Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ... -
Investigation of a glioblastoma risk-associated SNP of the PTPRB Gene in familial glioblastoma
Sevim Nalkıran, Hatice; Rakıcı, Sema Yılmaz; Nalkıran, İhsan (Turkiye Klinikleri, 2023)Objective: To investigate the association of the single nucleotide polymorphism (SNP) rs2252784 in the protein tyrosine phos-phatase receptor type B (PTPRB) gene with familial glioblastoma multiforme (GBM). Material and ... -
An investigation of ensemble learning methods in classification problems and an application on non-small-cell lung cancer data
Kıvrak, Mehmet; Çolak, Cemil (Effect Publishing Agency ( EPA ), 2022)This study aims to classify NSCLC death status and consists of patient records of 24 variables created by the open-source dataset of the cancer data site. Besides, basic classifiers such as SMO (Sequential Minimal ... -
Investigation of Gpx1 gene expression, serum Gpx1 and selenium levels on colorectal cancer
İplik, Elif Sinem; Nalkıran, İhsan; Turan, Saime; Arıkan, Soykan; Yaylım, İlhan; Ergen, Hayriye Arzu (Marmara Üniversitesi, Sağlık Bilimleri Enstitüsü, 2019)Objective: Colorectal cancer is one of the first lines when examined the death cause of cancer. It is well known that family history, and racial and ethnic background and daily life are related with colorectal cancer and ... -
Investigation of the relationship between oxidative stress and SCUBE1 levels in high fat diet-induced obese rats
Bodur, Akın; Kahraman, Cemil; Altay, Diler Us; Rendı, Taghi Ahmadi; Menteşe, Ahmet; Alver, Ahmet (2018)Background/aim: This study aimed to investigate signal peptide-Cub-EGF domain-containing protein 1 (SCUBE1) levels and oxidative stress (OS) in a high fat diet (HFD)-induced obese rat model. Materials and methods: Fourteen ... -
Less use of the bipolar cautery can prevent postlaminectomy epidural fibrosis: an experimental study in rats
AIM: To investigate the role of bipolar electrocautery in the occurrence of epidural fibrosis following lumbar spine laminectomy in a rat model. MATERIAL and METHODS: Fourteen male Sprague–Dawley rats (age: 4–6 months, ... -
Molecular epidemiology, antimicrobial resistance and characterization of extended-spectrum beta-lactamases of salmonella enterica serotype paratyphi B clinical Isolates
Bayramogğu, Gülçin; Özgümüş, Osman Birol; Kolaylı, Fetiye; Kamburoğlu, Ahu; Beşli, Yeşim; Dinç, Uğur; Tosun, İlknur; Aydın, Faruk (Ankara Microbiology Soc, 2014)Although Salmonella enterica serotype Paratyphi B is the less frequently isolated serotype worldwide and in Turkey, it is the most common serotype in our hospital, with a marked increase in 2007. the purpose of this study ... -
PaCaHa inhibits proliferation of human cancer cells in vitro
Background/aim: The aim of this study was to investigate the antiproliferative and cytotoxic effects of a newly synthesized molecule named paracetamol acetohydroxamic acid (PaCaHa) on human neoplastic cell lines. Materials ... -
The protective effect of syringic acid on ischemia injury in rat brain
Güven, Mustafa; Aras, Adem Bozkurt; Topaloğlu, Naci; Özkan, Adile; Şen, Halil Murat; Kalkan, Yıldıray; Okuyucu, Ali; Akbal, Ayla; Gökmen, Ferhat; Coşar, Murat (2015)Background/aim: Brain ischemia and treatment are important topics in neurological science. Free oxygen radicals and inflammation formed after ischemia are accepted as the most significant causes of damage. Currently there ... -
Protective roles of Cimin grape tissues on oxidative stress markers in the cellular system model
Aim: To analyze the phenolic composition of the Cimin grape, which is 1 of 2 grape varieties with a protected geographical indication in Turkey and is used locally to treat the symptoms of some disorders such as impotence ... -
Rize ilinde hemodiyaliz hastalarında HBsAg, Anti-HBs ve Anti-HCV seroprevalansı
Çopur, Ayşegül Çiçek; Şahin, Osman Zikrullah; Topaloğlu, Mustafa Kemal; Taşkaya, Ayşe Asena Kazancı; Yenilmez, İsmail Hakkı; Şahin, Kazım; Gündoğdu Ulusan, Deniz Zehra (2013)Amaç: Viral hepatitler hemodiyaliz ünitelerinde hem çalışan hem hastalar için önemli bir risk olmaya devam etmektedir. Enfeksiyon kontrol önlemlerinin ve aşılamanın düzenli yapıldığı diyaliz ünitelerinde hepatit B virus ... -
Sciatic nerve injury following analgesic drug injection in rats: a histopathological examination
Bostan, Habib; Çabalar, Murat; Altınay, Serdar; Kalkan, Yıldıray; Tümkaya, Levent; Kanat, Ayhan; Koçer, Abdulkadir (Kare PUBL, 2018)OBJECTIVE: Sciatic nerve neuropathy can be observed following intramuscular gluteal injections. The histopathological examination of sciatic nerve damage following intramuscular injection in the gluteal region for acute ... -
Seroprevalence of toxoplasma, rubella and cytomegalovirus in women of fertility age in our region
Bahçeci, İlkay; Karaca, Esra; Duran, Ömer Faruk; Aksoy, Duygu; İbik, Yunus Emre; Kırcı, Umut Buğra (Galenos Publishing, 2023)Objective: Toxoplasma gondii (T. gondii), Rubella and Cytomegalovirus (CMV) infections can cause severe morbidity in the fetus when transmissed during pregnancy. In our study, it was aimed to examine the seropositivity ...