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Toplam kayıt 403, listelenen: 391-400
Indenoquinoxaline-phenylacrylohydrazide hybrids as promising drug candidates for the treatment of type 2 diabetes: In vitro and in silico evaluation of enzyme inhibition and antioxidant activity
(Elsevier, 2024)
Existing drugs that are being used to treat type-2 diabetes mellitus are associated with several side effects; thus, exploring potential drug candidates is still an utter need these days. Hybrids of indenoquinoxaline and ...
Synthesis and biological evaluation of coumarin-amino acid-benzotriazole conjugates
(Springer, 2024)
Objective: It is aimed to synthesize new amino acid-conjugated coumarin-benzotriazole molecules and to investigate their acetylcholinesterase, urease, and lipase inhibition properties. Methods: Urease inhibitory activities ...
Effect of environmental pollution on nutritional indices and the phenoloxidase activity of agelastica alni (Coleoptera: Chrysomelidae) larvae
(Springer, 2024)
Abstract: The present study investigated the nutritional indices and immune responses of Agelastica alni L. larvae in heavy metal pollution (cadmium, zinc, copper, nickel, and iron). Larvae collected from 2 different ...
Human health risk assessment of heavy metals accumulation in different genders and tissues of whiting fish (Merlangius merlangus euxinus Nordmann, 1840) from Rize, Turkey
(Elsevier, 2024)
The contamination of fish resulting from marine pollution is a major concern, as it poses potential adverse effects on human health. Therefore, heavy metal concentrations (Cr, Fe, Ni, Cu, Zn, and Pb) in different genders ...
Experimental and computational studies on 4-[(3,5-dimethyl-1H-pyrazol-1-yl) methoxy]phthalonitrile and synthesis and spectroscopic characterization of its novel phthalocyanine magnesium(ii) and tin(ii) metal complexes
(Elsevier B.V., 2013)
The molecular structure of the substituted phthalonitrile was analyzed crystallographically and compared with optimized geometric structure. The structural properties of the compound such as energy, vibrational frequency, ...
Microwave-assisted synthesis of some 1, 2, 4-triazol-3-ones and potentiometric determination of their pKa in amfiprotic and dipolar aprotic-water mixtures
(0-Belirlenecek, 2013)
The novel 5-alkyl(aryl)-4-(aryl)-2, 4-dihydro-3H-1, 2, 4-triazol-3-ones (1-12) were synthesized by reaction of (N?-ethoxycarbonyl)-4-alkyl(aryl)hydrazonic acid ethyl ester with primary amines by microwave irradiation. ...
Synthesis and in vitro antioxidant activities of novel 4-(3-methyl-2- thienylmethyleneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives with their acidic properties
(2013)
In the present study 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5- ones 2a-i reacted with 3-methyl-thiophene-2-carboxyaldehyde to afford the corresponding 3-alkyl(aryl)-4-(3- methyl-2-thienylmethyleneamino)-4,5-dihydro- ...
Evaluation of phenolic compounds in Tilia rubra Subsp. caucasica by HPLC-UV and HPLC-UV-MS/MS
(Taylor & Francis Ltd., 2014)
Profile of phenolic compounds of Tilia rubra subsp. caucasica was measured by high performance liquid chromatography coupled with ultraviolet and tandem mass spectroscopy. Three different extraction methods (methonolic, ...
An efficient synthesis of some new bisbenzimidazoles via microwave technique
(2014)
2,2’-[1,4 (1,3)-Phenylenedi(methylene)]bis-1 H -benzimidazole derivatives were obtained from the reaction of 1,4- or (1,3)-bisiminoester hydrochloride and o -phenylenediamine derivatives under microwave irradiation. Ester ...
Synthesis of benzimidazoles containing piperazine ring as potential therapeutic agents against diabetes mellitus and antioxidant activities
(Elsevier, 2024)
We synthesized a novel 6-(4-substitue-piperazin-1-yl)-2-aryl-1H-benzimidazole derivatives starting from 5-(4-substitue-piperazin-1-yl)-2-nitroaniline with different aldehydes. A quick "onepot" nitro reductive cyclization ...