Yayıncı "Elsevier" TF, Temel Tıp Bilimleri Bölümü Koleksiyonu için listeleme
Toplam kayıt 35, listelenen: 1-20
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Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus
(Elsevier, 2023)Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side ef-fects, including cognitive impairment. Agomelatine, a synthetic melatonin analogue, is an important antide-pressant. ... -
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
(Elsevier, 2021)It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ... -
The assessment of neuronal plasticity following sciatic nerve injuries in rats using electron microscopy and stereological methods
(Elsevier, 2024)The transmission of signals to the cell body from injured axons induces significant alterations in primary sensory neurons located in the ganglion tissue, the site of the perikaryon of the affected nerve fibers. Disruption ... -
Association between rs11362 polymorphism in the beta-defensin 1 (DEFB1) gene and dental caries: A meta-analysis
(Elsevier, 2020)Objectives: Beta-defensin 1, encoded by the DEFB1 gene, is an important molecule that confers protection from dental caries. Numerous studies have been conducted on the rs11362 polymorphism in the DEFB1 gene. We evaluated ... -
COVID-19 infection produces subarachnoid hemorrhage; acting now to understand its cause: A short communication
(Elsevier, 2021)In the medical literature, some case reports on the association of the COVID-19 infection and occurrence of spontaneous subarachnoid hemorrhage (SAH)have been reported Aim of the present paper is to search the causes of ... -
The CYP 2C19*2 and CYP2C19*17 polymorphisms play a vital role in platelet responsiveness to clopidogrel after percutaneous coronary intervention: a pharmacogenomic study
(Elsevier, 2015)Background: Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor. Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current guidelines for patients ... -
Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey
(Elsevier, 2013)Objective: To investigate the antibiotic resistance genes inserted into class 1 and class 2 integrons in Acinetobacter baumannii (A. baumannii) isolates obtained from nine different cities in Turkey. Methods: A collection ... -
Dexamethasone and concentrated growth factors on peripheral nerve injury: A clinic-relevant animal study
(Elsevier, 2024)Background: Mandibular nerve injury is a common clinical condition that affects clinicians’ management and patients’ quality of life. In the literature, there are various effective treatments available. The primary purpose ... -
The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology
(Elsevier, 2019)Background: the most commonly used insecticides and pesticides worldwide are organophosphate compounds, chemicals that irreversibly inhibit the cholinesterase enzyme. Acute intoxication with cholinesterase inhibitors is ... -
The effect of royal jelly on CD3+, CD5+, CD45+ T-cell and CD68+ cell distribution in the colon of rats with acetic acid-induced colitis
(Elsevier, 2012)Background: Traditional medicines and health supplements have historically been used to treat many illnesses but most of them have not been evaluated objectively to prove their efficacy. We have been investigating the ... -
The effects of Garcinia kola and curcumin on the dorsal root ganglion of the diabetic rat after peripheral nerve transection injury
(Elsevier, 2024)Objective: To test the protective effects of Garcinia kola and curcumin on the ganglion tissues of diabetic rats following the use of autologous vein graft in peripheral nerve transection injury. Methods: The sciatic nerve ... -
Effects of melatonin on islet neogenesis and beta cell apoptosis in streptozotocin-induced diabetic rats: An immunohistochemical study
(Elsevier, 2012)This investigation was carried out to explore the antidiabetic, antiapoptotic and neogenetic effects of melatonin (MLT) in streptozotocin-induced diabetic rats. Sixty-four male rats were assigned randomly to one of four ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
(Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
Elevated serum osteoprotegerin levels predict in-hospital major adverse cardiac events in patients with ST elevation myocardial infarction
(Elsevier, 2012)The aim of our study was to investigate whether osteoprotegerin (OPG) is related to in-hospital major adverse cardiac events (MACE) and reperfusion parameters in patients with ST elevation myocardial infarction (STEMI). ... -
Estimation of cerebral surface area using vertical sectioning and magnetic resonance imaging: A stereological study
(Elsevier, 2010)Stereological techniques using isotropic uniform random and vertical uniform random sections have been used for surface area estimation. However, there are a few studies in which the surface area of the brain is estimated ... -
Heavy metal resistance of marine bacteria on the sediments of the Black Sea
(Elsevier, 2022)The Black Sea is unfortunately globally established as a highly polluted sea, with contaminants from various sources polluting its marine sediments. This study aimed at analyzing heavy metal resistance levels by heterotrophic ... -
Identification of the potential matrix protein of invertebrate iridescent virus 6 (IIV6)
(Elsevier, 2023)Invertebrate iridescent virus 6 (IIV6) is a nucleocytoplasmic virus with a similar to 212 kb linear dsDNA genome that encodes 215 putative open reading frames (ORFs). Proteomic analysis has revealed that the IIV6 virion ... -
Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats
(Elsevier, 2013)Melatonin is an important antioxidant, and through its anti-inflammatory effects it can control immune responses, oxidative stress, and defense cell infiltration. Periodontitis is a disease of the oral cavity and the ... -
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
(Elsevier, 2019)Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ... -
Long-term protective effects of lamotrigine in a rat ovarian ischemia-reperfusion model
(Elsevier, 2024)Ovarium torsion is a gynecological emergency that is common in women of reproductive age and requires early diagnosis and intervention. In this study, we aimed to investigate the long-term anatomical, histological and ...