Konu "Oxidative stress" için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 80, listelenen: 1-20
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Adalimumab ameliorates abdominal aorta cross clamping which induced liver injury in rats
(Hindawi Ltd, 2014)The aim of this study was to investigate the possible protective effects of adalimumab (ADA) on cell damage in rat liver tissue during ischemia/reperfusion (I/R) injury of infrarenal abdominal aorta. Thirty male Wistar-albino ... -
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
Assessment of thiol/disulphide homeostasis in patients with knee osteoarthritis
(CSIR-National Institute of Science Communication and Policy Research (CSIR-NIScPR), 2021)Our aim was to explore the thiol/disulphide homeostasis and the link with functional status in patients who have knee OA. Sixty knee OA patients and 50 healthy individuals were enrolled in this study. We measured serum ... -
Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension
(Taylor & Francis Inc, 2016)Human serum paraoxonase 1 (PON1) is carried by high-density lipoprotein in blood circulation and is shown to be effective in preventing oxidized phospholipids carried by low-density lipoprotein particles, thus it acts as ... -
Biochemical and pathological changes in the male rat kidney and bladder following exposure to continuous 900-MHz electromagnetic field on postnatal days 22-59
(Taylor & Francis Ltd, 2017)Purpose: To investigate the effect on male rat kidney and bladder tissues of exposure to 900-megahertz (MHz) electromagnetic field (EMF) applied on postnatal days 22-59, inclusive. Materials and methods: Twenty-four male ... -
Carbonic anhydrase I-II autoantibodies and oxidative status in long-term follow-up of patients with Crimean-Congo haemorrhagic fever
(Taylor & Francis Ltd, 2018)Context: Crimean-Congo haemorrhagic fever (CCHF) is a life-threatening acute febrile haemorrhagic disease. Objective: This study was to measure levels of the oxidative stress biomarkers malondialdehyde (MDA), total oxidant ... -
Comparison of effects of dexmedetomidine and amifostine against X-ray radiation-induced parotid damage
(Springer, 2022)Radiotherapy can be employed as a therapeutic modality alone in the early stages of cancer and is used together with other treatments such as surgery and chemotherapy in more advanced stages. However, exposure to ionizing ... -
Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer
(Int Inst Anticancer Research, 2015)Background/Aim: Oxidative stress plays a role on the development of colorectal cancer. Manganese superoxide disnzutase (MnSOD) and glutathione peroxidase I (GPXI) are crucial in regulating oxidative balance and its ... -
Dexmedetomidine alleviates vacuolization and necrosis in tubular epithelial cells induced by aortic cross-clamping
(Verduci Publisher, 2023)OBJECTIVE: Acute kidney inju-ry (AKI) is one of the main causes of mortality in patients undergoing emergency surgery due to an abdominal aortic aneurysm. This study aimed to determine the potential nephroprotec-tive ... -
Dexmedetomidine attenuates pneumocyte apoptosis and inflammation induced by aortic ischemia-reperfusion injury
(Taylor & Francis Ltd., 2022)Objective Despite significant improvements in interventional vascular aneurysm repair procedures and intensive care patient management, there has been no significant decrease in mortality due to ruptured abdominal aortic ... -
Did diet compliance and remission reduce oxidative stress in celiac patients?
(Associacao Medica Brasileira, 2024)OBJECTIVE: We aimed to examine the effect of remission status on thiol–disulfide homeostasis in celiac patients and thus to indirectly determine the effect of oxidative stress and inflammation caused by non-compliance with ... -
Dynamic thiol/disulphide balance in patients undergoing hypotensive anesthesia in elective septoplasties
(Wiley-Hindawi, 2021)Objective We aimed to investigate the effects of hypotensive anaesthesia on oxidative stress with serum thiol/disulphide balance in patients undergoing elective septoplasty procedures under general anaesthesia. Methods ... -
The effect of bee pollen on reproductive and biochemical parameters in methotrexate-induced testicular damage in adult rats
(De Gruyter Open Ltd., 2021)Objectives: Methotrexate (MTX) is an anticancer drug used in chemotherapy. MTX was known for its toxic effects involving most of the organs including testis. Bee pollen is healthy food for human and has antioxidant effect. ... -
The effect of hesperidin and quercetin on oxidative stress, NF-kappa B and SIRT1 levels in a STZ-induced experimental diabetes model
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Objective: the aim of this study is to investigate the roles of SIRT1 and NF-kappa B in the pathogenesis of diabetes mellitus in rats with STZ-induced diabetes and determine the effects of hesperidin and quercetin on ... -
Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats
(E-Century Publishing Corp, 2015)This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ... -
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
(Taylor & Francis Ltd., 2022)Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ... -
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats
(Taylo & Francis Ltd., 2021)Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ... -
Effects of astaxanthin on biochemical and histopathological parameters related to oxidative stress on testes of rats on high fructose regime
(Wiley, 2018)Astaxanthin (ASX) is a xanthophyll family of hydroxycarotenoids which contains several double bonds. It is produced by Haemococcus pluvialis, a microalgae and possesses antioxidant and anti-inflammatory properties. the aim ... -
Effects of bone marrow-derived mesenchymal stem cells on doxorubicin-induced liver injury in rats
(Wiley, 2022)Doxorubicin (DOX) is a potent chemotherapeutic agent and has toxic effects on various organs, including the liver. In the current study, we aimed to investigate the effects of bone-marrow-derived mesenchymal stem cell ... -
The effects of dexmedetomidine against ruptured abdominal aortic aneurysm injury to myocardial tissue induced by abdominal aorta clamping
(Effect Publishing Agency ( EPA ), 2021)Objectives: This study aims to examine the potential protective effect of the selective alpha-2 adrenergic receptor agonist dexmedetomidine (DEX) against aortic occlusion-induced myocardial injury. Patients and methods: ...