Ara
Toplam kayıt 31, listelenen: 11-20
The protective effect of syringic acid on ischemia injury in rat brain
(2015)
Background/aim: Brain ischemia and treatment are important topics in neurological science. Free oxygen radicals and inflammation formed after ischemia are accepted as the most significant causes of damage. Currently there ...
Topiramate has protective effect on renal injury
(Comenius Univ, 2015)
Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ...
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ...
Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period
(Iniestares, S.A., 2015)
OBJECTIVES: Electromagnetic radiation (ER) emitted from cell phones may exert a detrimental influence on human health and may affect the man reproductive system. We aimed to study the biological and morphological effects ...
Neuroprotective effect of p-coumaric acid in rat model of embolic cerebral ischemia
(Mashhad Univ Med Sciences, 2015)
Objective(s): Stroke poses a crucial risk for mortality and morbidity. Our study aimed to investigate the effect of p-coumaric acid on focal cerebral ischemia in rats. Material and Methods: Rats were randomly divided into ...
Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats
(E-Century Publishing Corp, 2015)
This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ...
Effect of infliximab on renal injury due to methotrexate in rat
(Iranian Soc Nephrolgy, 2015)
Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective ...
Histopathological effects of intramuscular metamizole sodium on rat sciatic nerve
(Mashhad Univ Med Sciences, 2016)
Objective(s): We investigated the histopathological effects of metamizole sodium (MS) on the sciatic nerve. Materials and Methods: This study was performed using 48 adult male Wistar albino rats. Ten groups were constituted ...
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
(Wroclaw Medical Univ, 2016)
Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ...
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
(Verduci Publisher, 2016)
OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ...