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Toplam kayıt 24, listelenen: 11-20
Kinetic characterization of GES-22 beta-lactamase harboring the M169L clinical mutation
(Japan Antibiotics Research Assoc, 2016)
The class A p-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a ...
PaCaHa inhibits proliferation of human cancer cells in vitro
(2016)
Background/aim: The aim of this study was to investigate the antiproliferative and cytotoxic effects of a newly synthesized molecule named paracetamol acetohydroxamic acid (PaCaHa) on human neoplastic cell lines. Materials ...
A Novel integron gene cassette harboring VIM-38 Metallo-beta-lactamase in a clinical pseudomonas aeruginosa isolate
(Korean Soc Laboratory Medicine, 2016)
Dear Editor,
Multidrug resistance of Pseudomonas aeruginosa has been attributed to both intrinsic and acquired antibiotic-resistance mechanisms. Multidrug-resistant (MDR) P. aeruginosa isolates have become a serious ...
Three seasonal comprehensive evaluation process of Digitalis trojana Ivan's phenolics
(Elsevier Science Bv, 2016)
Digitalis trojana Ivan, a member of Digitalis genus, has highly bioactive properties due to, efficient phenolics. These compounds have shown to convert into each other in a limited time. Seasonal fluctuations of this plant ...
Characterization of class 1 and class 2 integron gene cassettes in escherichia coil strains isolated from urine cultures: A multicenter study
(Ankara Microbiology Soc, 2016)
Escherichia coli is the most common pathogen isolated from both nosocomial and community acquired urinary tract infections. Although there are many studies from different centers concerning the antibiotic susceptibility ...
Comparison of verona integron-borne metallo-beta-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(Amer Soc Microbiology, 2016)
Metallo-beta-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. the Verona integron-borne metallo-beta-lactamase ...
Determination of the staphylococcal cassette chromosome in methicillin-resistant Staphylococcus aureus strains isolated from various clinical samples
(Science & Innovation, Ltd, 2016)
Aim - the present study aimed to detect mecA and staphylococcal cassette chromosome mec (SCCmec) types in methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from various clinical samples in two university ...
High prevalence of NDM metallo-β-lactamase among ESBL-producing Escherichia coli İsolates
(Akademiai Kiado Zrt, 2017)
Resistance to beta-lactams in Enterobacteriaceae has been increasing worldwide. This study aimed to determine the frequency of beta-lactamase genes and antibiotic resistance rates of 140 extended-spectrum beta-lactamase ...
Evaluation of the carbapenem inactivation method for detection of carbapenemase-producing gram-negative bacteria in comparison with the RAPIDEC CARBA NP
(Mary Ann Liebert, Inc, 2017)
Timely detection of carbapenemases by both phenotypic and genotypic methods is essential for developing strategies to control the spread of infections by carbapenem-resistant isolates and related morbidity and mortality. ...
Effect of mazEF, higBA and relBE toxin-antitoxin systems on antibiotic resistance in Pseudomonas aeruginosa and Staphylococcus isolates
(Med Coll Malawi, 2018)
Background A toxin-antitoxin (TA) system is a set of two or more closely linked genes that are encoded as a poison and a corresponding antidote on a protein. in typical bacterial physiology, an antitoxin binds to a toxin ...