Ara
Toplam kayıt 544, listelenen: 161-170
Comparison of verona integron-borne metallo-beta-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(Amer Soc Microbiology, 2016)
Metallo-beta-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. the Verona integron-borne metallo-beta-lactamase ...
The role of RAAS inhibition by aliskiren on paracetamol-induced hepatotoxicity model in rats
(Wiley, 2016)
Paracetamol is one of the most popular and widely used analgesic and antipyretic agents, but an overdose can cause hepatotoxicity and lead to acute liver failure. Aliskiren directly inhibits renin which downregulates the ...
Determination of genotypic and phenotypic characteristics of friedreich's ataxia and autosomal dominant spinocerebellar ataxia types 1, 2, 3, and 6
(Aves, 2016)
Introduction: This study aimed to analyze the genotypic characteristics of Friedreich's ataxia (FA) and autosomal dominant ataxias [such as spinocerebellar ataxia (SCA) types 1, 2, 3, and 6] using molecular and biological ...
Biochemical, histopathological and immunohistochemieal evaluation of the protective and therapeutic effects of thymoquinone against ischemia and ischemia/reperfusion injury in the rat ovary
(Karger, 2016)
Aim: To evaluate the antioxidant effects of thymoquinone (TQ) and to investigate the biochemical, histopathological and immunohistochennical changes in experimental rat ovarian torsion. Methods: A total of 48 female adult ...
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
(Mashhad Univ Med Sciences, 2016)
Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ...
Protective effects of estrogen and bortezomib in kidney tissue of post-menopausal rats: an ultrastructural study
(Taylor & Francis Ltd, 2016)
Purpose: Symptoms and disorders related to menopause and its associated estrogen deficiency have become a considerable health concern worldwide. Ovarian hormone depletion/estrogen deficiency can be usefully studied using ...
Effects of long-term exposure to 900 megahertz electromagnetic field on heart morphology and biochemistry of male adolescent rats
(Taylor & Francis Ltd, 2016)
The pathological effects of exposure to an electromagnetic field (EMF) during adolescence may be greater than those in adulthood. We investigated the effects of exposure to 900 MHz EMF during adolescence on male adult rats. ...
Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension
(Taylor & Francis Inc, 2016)
Human serum paraoxonase 1 (PON1) is carried by high-density lipoprotein in blood circulation and is shown to be effective in preventing oxidized phospholipids carried by low-density lipoprotein particles, thus it acts as ...
A multicenter evaluation of blood culture practices, contamination rates, and the distribution of causative bacteria
(Ahvaz Jundishapur Univ Med Sci, 2016)
Background: the prognostic value of blood culture testing in the diagnosis of bacteremia is limited by contamination. Objectives: in this multicenter study, the aim was to evaluate the contamination rates of blood cultures ...
Relationship of serum osteoprotegerin with arterial stiffness, preclinical atherosclerosis, and disease activity in patients with ankylosing spondylitis
(Springer London Ltd, 2016)
Patients with ankylosing spondylitis (AS) reportedly have a higher mortality and morbidity risk. Osteoprotegerin (OPG) was recently defined as an important cardiovascular (CV) marker in the general population. We aimed to ...