Ara
Toplam kayıt 22, listelenen: 1-10
Protective effect of astaxanthin against cisplatin-induced gastrointestinal toxicity in rats
(Springer Wien, 2022)
Background the aim of the present study was to demonstrate astaxanthin's attenuating effects against cisplatin (CIS)-induced gastrointestinal toxicity in a rat model. Methods Thirty-two Wistar rats (weight 200-250 g) were ...
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
(Elsevier, 2021)
It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ...
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats
(Taylo & Francis Ltd., 2021)
Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ...
Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress
(Elsevier Ireland Ltd., 2021)
Chronic stress is a potential problem associated with anxiety, depression, and cognitive dysfunction. Bee pollen, a powerful antioxidant, has many therapeutic effects. In this study, we aimed to examine the effects of one ...
Periodontitis exacerbates the renal degenerative effects of obesity in rats
(Wiley, 2021)
Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ...
Influences of periodontitis on hippocampal inflammation, oxidative stress, and apoptosis in rats
(Wiley, 2021)
Background and aim The hippocampus, which has a central role in cognitive and behavioral activities, is one of the most sensitive parts of the brain to systemic inflammatory diseases. This animal study aims to comprehensively ...
Melatonin improves periodontitis-induced kidney damages by decreasing inflammatory stress and apoptosis in rats
(Wiley-Blackwell, 2020)
Background: Two main aims of this animal study were to inspect the possible effects of periodontitis on the structure and functions of the kidneys and the therapeutic effectiveness of melatonin. Methods: Twenty-four male ...
Lasting hepatotoxic effects of prenatal mobile phone exposure
(Taylor & Francis Ltd, 2017)
Objective: in this study, the livers of rats born to mothers exposed to electromagnetic field (EMF) were examined 60 days postpartum for biochemical and histopathological changes.Methods: Pregnant rats were exposed to ...
Effects of gadolinium-based MRI contrast agents on liver tissue
(Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...