Ara
Toplam kayıt 58, listelenen: 21-30
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
(Taylor & Francis Ltd., 2022)
Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ...
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway
(Wiley, 2022)
Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ...
Effect of the prenatal electromagnetic field exposure on cochlear nucleus neurons and oligodendrocytes in rats
(Springer Heidelberg, 2022)
Electromagnetic radiation from elecromagnetic field (EMF) sources has been an important health concern for a long time. The vast majority of this exposure is due to the widespread use of mobile phones, an important source ...
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
(Elsevier, 2022)
Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ...
Histopathological evaluation of the effects of dexmedetomidine against pituitary damage ınduced by X-ray irradiation
(Taylor & Francis Ltd., 2022)
Background: The present study, aimed to investigate the potential negative effects of x-ray radiation and the effects of the α2-adrenergic receptor agonist dexmedetomidine on the pituitary gland. Methods: Twenty-four ...
Biochemical and histopathological investigation of liver tissues on high fat diet fed rats
(Galenos Yayıncılık, 2022)
Objective: Hepatic steatosis is a common cause of liver disease and has become more prevalent recently. This study was conducted to investigate the biochemical and histopathological changes in the liver tissue high fat ...
Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity
(Wroclaw Medical Univ, 2018)
Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ...
Effects of gadolinium-based contrast agents on submandibular gland tissue in rats
(Springer, 2018)
The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on ...
Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats
(Sage Publications Ltd, 2018)
Paracetamol (P), one of the most popular and commonly used analgesic and antipyretic agents, causes hepatotoxicity in overdoses. Amlodipine (AML), an L-type calcium channel blocker, has been shown to have anti-inflammatory ...
Effects of gadolinium-based MRI contrast agents on liver tissue
(Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...