Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 700, listelenen: 521-540
-
Investigation of the cyp3a4 and pon1 gene variants in turkish patients with familial coronary artery disease
(Lippincott Williams & Wilkins, 2015)Objective: Coronary artery disease (CAD), a complex multifactorial disorder, has been suggested to be associated by the interaction of both environmental and genetic risk factors. -
A promoter polymorphism in the PON1 gene is associated with essential hypertension
(Lippincott Williams & Wilkins, 2015)Objective: Increased vascular oxidative stress, the main risk factor of cardiovascular diseases, is seen as a role in the pathophysiology of essential hypertension. Genetic factors also play an important role in the ... -
Genistein exerts neuroprotective effect on focal cerebral ischemia injury in rats
(Springer/Plenum Publishers, 2015)Brain ischemia and treatment are one of the important topics in neurological science. Free oxygen radicals and inflammation formed after ischemia are accepted as the most important causes of damage. Currently, there are ... -
Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation
(Pergamon-Elsevier Science Ltd, 2015)Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain ... -
Pleiotropic effects of HDL subfractions and HDL-associated enzymes on protection against coronary artery disease
(Taylor & Francis Ltd, 2015)Objective High-density lipoprotein cholesterol (HDL-C) levels are inversely related to the risk of coronary artery disease (CAD). Alterations in HDL-C subclass distribution and HDL-associated enzyme activities may be more ... -
A novel model approach for esophageal burns in rats: a comparison of three methods
(Sage Publications Inc, 2015)Background: Corrosive esophageal injury causes serious clinical problems. We aimed to create a new experimental esophageal burn model using a single catheter without a surgical procedure. Materials and methods: We conducted ... -
Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period
(Iniestares, S.A., 2015)OBJECTIVES: Electromagnetic radiation (ER) emitted from cell phones may exert a detrimental influence on human health and may affect the man reproductive system. We aimed to study the biological and morphological effects ... -
Determination of tritium concentrations in humans before the development of a nuclear power plant in Turkey
(Taylor & Francis Ltd, 2015)The most widely used method to determine the level of tritium in humans is testing urine. Tritium concentrations in urine samples of 100 persons aged 18-66 years selected randomly from a pilot region in Turkey were analysed. ... -
Effects of chronic exposure to electromagnetic waves on the auditory system
(Taylor & Francis Ltd, 2015)Conclusion: the results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. Objectives: Numerous researches have been done about the risks of ... -
The CYP 2C19*2 and CYP2C19*17 polymorphisms play a vital role in platelet responsiveness to clopidogrel after percutaneous coronary intervention: a pharmacogenomic study
(Elsevier, 2015)Background: Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor. Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current guidelines for patients ... -
Effect of sugammadex on rocuronium induced changes in pancreatic mast cells
(Sage Publications Inc, 2015)Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ... -
The effects of prenatal exposure to a 900-MHz electromagnetic field on the 21-day-old male rat heart
(Taylor & Francis Inc, 2015)The growing spread of mobile phone use is raising concerns about the effect on human health of the electromagnetic field (EMF) these devices emit. the purpose of this study was to investigate the effects on rat pup heart ... -
Can prenatal exposure to a 900 MHz electromagnetic field affect the morphology of the spleen and thymus, and alter biomarkers of oxidative damage in 21-day-old male rats?
(Taylor & Francis Ltd, 2015)We investigated the effects of a 900 Megahertz (MHz) electromagnetic field (EMF), applied during the prenatal period, on the spleen and thymus of 21-day-old male rat pups. Pregnant Sprague-Dawley rats were divided into ... -
Evaluation of carbapenem resistance using phenotypic and genotypic techniques in Enterobacteriaceae isolates
(Bmc, 2015)Background: Bacterial resistance to antibiotics is increasing worldwide. Antibiotic-resistant strains can lead to serious problems regarding treatment of infection. Carbapenem antibiotics are the final treatment option for ... -
Distribution of beta-lactamase genes among carbapenem-resistant klebsiella pneumoniae strains isolated from patients in Turkey
(Korean Soc Laboratory Medicine, 2015)Background: the emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the beta-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ... -
Neurotoxicity of various root canal sealers on rat sciatic nerve: an electrophysiologic and histopathologic study
(Springer Heidelberg, 2015)Objectives the aim of this study was to compare the neurotoxicity of various root canal sealers on rat sciatic nerve by electrophysiologic and histopathologic analyses. Materials and methods A total of 40 male rats were ... -
Protective effects of infliximab on lung injury induced by methotrexate
(Elsevier Espana Slu, 2015)Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ... -
Anthocyanins profiling of Thymus praecox opiz subsp caucasicus var. caucasicus
(Elsevier Science Bv, 2015)Thymus praecox Opiz subsp. caucasicus var. caucasicus (Anzer tea) was studied to determine its anthocyanin content; anthocyanin stability in response to acidic hydrolysis and temperature changes. in this study, anthocyanin ... -
A multicenter evaluation of blood culture practices, contamination rates, and the distribution of causative bacteria
(Ahvaz Jundishapur Univ Med Sci, 2016)Background: the prognostic value of blood culture testing in the diagnosis of bacteremia is limited by contamination. Objectives: in this multicenter study, the aim was to evaluate the contamination rates of blood cultures ... -
Biochemical, histopathological and immunohistochemieal evaluation of the protective and therapeutic effects of thymoquinone against ischemia and ischemia/reperfusion injury in the rat ovary
(Karger, 2016)Aim: To evaluate the antioxidant effects of thymoquinone (TQ) and to investigate the biochemical, histopathological and immunohistochennical changes in experimental rat ovarian torsion. Methods: A total of 48 female adult ...
