Browsing FEF, Kimya Bölümü Koleksiyonu by Author "Kahveci, Bahittin"
Now showing items 21-40 of 59
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Microwave-assisted synthesis of new benzimidazole derivatives with lipase inhibition activity
Menteşe, Emre; Bektaş, Hakan; Ülker, Serdar; Bekircan, Olcay; Kahveci, Bahittin (Taylor & Francis Ltd, 2014)A practical protocol has been used for the synthesis of benzimidazoles. the reaction of iminoester hydrochlorides of phenylacetic with 4,5-dichloro-1,2-phenylenediamine under microwave irradiation leads to the benzimidazole ... -
Microwave-assisted synthesis of novel 2,4-dihydro-5-[4-(trifluoromethyl) phenyl]-3h-1,2,4-triazol-3-ones and potentiometric determination of their pKa in nonaqueous solvents
Özil, Musa; İslamoğlu, Fatih; Menteşe, Emre; Kahveci, Bahittin (Wiley, 2010)The novel 4-amino- or 4-aryl-substituted 2,4-dihydro-5-[(4-trifluoromethyl) phenyl]-3H-1,2,4-triazol-3-ones 3a-3g were synthesized by reaction of N-(ethoxycarbonyl)-4-(trifluoromethyl)benzenehydrazonic acid ethyl ester (2) ... -
Microwave-assisted synthesis of some 1, 2, 4-triazol-3-ones and potentiometric determination of their pKa in amfiprotic and dipolar aprotic-water mixtures
İslamoğlu, Fatih; Menteşe, Emre; Özil, Musa; Turumtay, Emine Akyüz; Kahveci, Bahittin (0-Belirlenecek, 2013)The novel 5-alkyl(aryl)-4-(aryl)-2, 4-dihydro-3H-1, 2, 4-triazol-3-ones (1-12) were synthesized by reaction of (N?-ethoxycarbonyl)-4-alkyl(aryl)hydrazonic acid ethyl ester with primary amines by microwave irradiation. ... -
Microwave-assisted synthesis of some 1H-1,2,4-triazol-3-one derivatives
Karaali, Nesrin; Menteşe, Emre; Yılmaz, Fatih; Usta, Asu; Kahveci, Bahittin (Bureau Scientific Publ, 2013)4-Amino-5-(methyl/ethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one were synthesized from the reaction of (methyl/ethyl)-ester ethoxycarbonyl hydrazone with hydrazine hydrate and then, converted to corresponding Schiff bases using ... -
Microwave-assisted synthesis of some 2-substituted quinazolin-4(3h)-one derivatives from imıioester hydrochlorides
Menteşe, Emre; Kahveci, Bahittin (Editura Acad Romane, 2014)Herein, a method that involves a reaction of iminoester hydrochloride with methyl anthranilate via microwave assisted synthesis is reported. This efficient procedure provides pure products within few minutes. This method ... -
Microwave-assisted synthesis of some 5(6)-nitro-1h-benzimidazoles and their hydrazide derivatives
Yılmaz, Fatih; Menteşe, Emre; Karaali, Nesrin; Kahveci, Bahittin (Chem Soc Ethiopia, 2013)A series of 5(6)-nitro-1H-benzimidazole and their hydrazide derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o-phenylenediamine under microwave irradiation. the structure of all synthesized ... -
Microwave-assisted synthesis of some new benzimidazole derivatives with their antimicrobial activity
Menteşe, Emre; Yılmaz, Fatih; Beriş, Fatih Şaban; Bekircan, Olcay; Kahveci, Bahittin (Bentham Science Publ Ltd, 2015)2-(2-Chlorobenzyl)-1H-benzimidazole (2) was prepared from the reaction of o-phenylenediamine and ethylimido-o-chlorophenylacetate hydrochloride (1) under microwave irradiation. the acetate and hydrazide derivatives of 2(2- ... -
Microwave-assisted synthesis of some new benzylidenamino compounds and potentiometric determination of their pKa
A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new benzylidenamino compounds (4a-f) ... -
Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Ülker, Serdar (Springer, 2015)By using the microwave technology, a new protocol has been developed for the synthesis of new coumarin derivatives including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly ... -
Microwave-assisted synthesis of some novel benzimidazole derivatives containing imine function and evaluation of their antimicrobial activity
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay (Wiley, 2014)4-Bromo-o-phenylenediamine and ethylimido-p-bromophenylacetate, 1, were subjected to microwave irradiation to synthesize benzimidazole derivative, compound 2. Ester derivative, 3, and hydrazide derivative, 4, of compound ... -
Microwave-promoted synthesis and biological activity of some 2-hetarylmethyl-4-(4-hetarylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one derivatives
Özil, Musa; Bodur, Osman; Ülker, Serdar; Kahveci, Bahittin (Springer, 2015)A series of fused and non-fused 1,2,4-triazole derivatives were prepared starting from ethyl 4-[1-(2-ethoxy-2-oxoethyl)-3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]benzoate. Firstly, both ethyl ester groups were ... -
Mıcrowave-assısted synthesıs of some novel benzımıdazole compounds contaınıng oxadıazole moıety
Kahveci, Bahittin; Sosan, Nesibe; Menteşe, Emre; Yılmaz, Fatih (Editura Acad Romane, 2013)5(6)-Nitro-2-alkyllaryl-1H-benzimidazoles were obtained from the reaction of iminoester hydrochlorides and 4-nitro-o-phenylenediamine, and converted to their ester and hydrazide derivatives. Hydrazide derivatives were used ... -
A new green protocol for the synthesis of 2-substituted perimidines from hydrazones under catalyst- and solvent-free conditions
Menteşe, Emre; Yılmaz, Fatih; Kahveci, Bahittin (Bulgarian Academy of Sciences, 2018)A new green protocol was developed for the synthesis of 2-substituted perimidines. The protocol involves a reaction of ethoxy carbonylhydrazone with 1,8-diaminonaphthalene under solvent- and catalyst-free conditions. Simple ... -
A Novel route to one-pot three-component synthesis of benzimidazo [2,1-b]-quinazolin-1-one derivatives
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Karaali, Nesrin (Bentham Science Publ Ltd, 2013)One-pot three-component synthesis of benzimidazo[2,1-b]-quinazolin-1-ones was efficiently performed under microwave irradiation and solvent-free condition. the method provides some advantages such as low cost, experimental ... -
Rapid and efficient microwave-assisted synthesis of some new triazol-3-one derivatives
Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Wiley, 2013)A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new triazol-3-ones via microwave ... -
Rapid and efficient synthesis of a new series of 2-aryl-5-fluoro-6(4-phenylpiperazin-1-yl)-1H-benzimidazoles using microwave heating
Menteşe, Emre; Yılmaz, Fatih; İslamoğlu, Fatih; Kahveci, Bahittin (Sage Publications Ltd, 2015)A new series of 2-aryl-5-fluoro-6-(4-phenylpiperazin-1-yl)-1H-benzimidazoles was synthesised from the reaction of 4-fluoro-5-(4-phenylpiperazin-1-yl) benzene-1,2-diamine and iminoester hydrochlorides. 4-Fluoro-5-(4-pheny ... -
Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives
Menteşe, Emre; Yılmaz, Fatih; Karaali, Nesrin; Ülker, Serdar; Kahveci, Bahittin (Maik Nauka/Interperiodica/Springer, 2014)This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. the structure of ... -
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
Özil, Musa; Emirik, Mustafa; Etlik, Semiha Yılmaz; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2016)A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ... -
Studies on the protonation constants of some triazoles in ethanol-water mixtures
İslamoğlu, Fatih; Kahveci, Bahittin; Özil, Musa; Akyüz, Emine (Chemical Publishing Co., 2008)Several studies, involving the formation and investigation of biological activities of some triazoles derivatives. These derivatives have weak acidic properties. To gain more information about the effect of solvent on ... -
Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies
Menteşe, Emre; Güner, Adem; Polatlı, Elifsu; Emirik, Mustafa; Bektaş, Hakan; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2020)The synthesis, docking study, and investigation of the anticancer activities of some coumarin derivatives containing the triazole ring are reported in this study. the newly synthesized compounds were screened for their in ...