Başlık için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 586, listelenen: 305-324
-
Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF)
(Nature Publishing Group, 2019)Recurrence in patients with glioblastoma (GBM) is inevitable resulting in short survival times, even in patients with O-6-Methylguanine-DNA Methyltransferase (MGMT) methylation. Other pathways must be activated to escape ... -
Identification of bacteria obtained from dactylorhiza urvilleana rhizoid region, metal tolerances, bioremidant characteristics and effects on maize germination in copper presence
(Galenos Yayıncılık, 2023)Rapidly increasing industrialization and technological developments cause hazardous wastes to spread to the environment at a high rate. In our study, three bacterial (5O1, 5O8, 112O1) strains isolated from the rhizoid ... -
Identification of the potential matrix protein of invertebrate iridescent virus 6 (IIV6)
(Elsevier, 2023)Invertebrate iridescent virus 6 (IIV6) is a nucleocytoplasmic virus with a similar to 212 kb linear dsDNA genome that encodes 215 putative open reading frames (ORFs). Proteomic analysis has revealed that the IIV6 virion ... -
Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats
(Elsevier, 2013)Melatonin is an important antioxidant, and through its anti-inflammatory effects it can control immune responses, oxidative stress, and defense cell infiltration. Periodontitis is a disease of the oral cavity and the ... -
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
(Springer, 2024)Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ... -
The impact of diurnal variation of PSA on timing of measurement in prostate biopsy
(Wiley, 2019)Background Prostate-specific antigen (PSA) synthesis is related to testosterone, which has a diurnal rhythm. PSA might have a diurnal variation and the timing of measurement could change the clinical practice for prostate ... -
The impact of resveratrol on oxidative stress induced by methotrexate in rat ileum tissue: evaluation of biochemical and histopathological features and analysis of gene expression
(Karger, 2016)Objective: the aim of this study was to assess the impact of resveratrol (RST) on oxidative stress induced by methotrexate in rat ileum tissue. Materials and Methods: Twenty-four rats were divided into 4 groups with 6 in ... -
In vitro activity of ceftaroline to MRSA isolates: a multicenter study
(Ankara Microbiology Soc, 2013)Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging pathogen that cause severe community- and hospital-acquired infections. Studies continue on searching alternatives due to the limited number of therapeutic ... -
In vitro cytotoxic, genotoxic and antioxidant/oxidant effects of guaiazulene on human lymphocytes
(Inst Tecnologia Parana, 2015)The aim of this study was to evaluate for the cytotoxicity, genotoxicity and antioxidant/oxidant activity of GYZ on human peripheral blood lymphocytes (PBLs). Guaiazulene (GYZ) was added into culture tubes at various ... -
In vitro cytotoxic, genotoxic, and oxidative effects of acyclic sesquiterpene farnesene
(2014)Farnesene (FNS) is an acyclic sesquiterpene. It has a wide range of important biological effects such as antioxidant, antimicrobial, and antifungal properties, although its cytotoxic, cytogenetic, and oxidative effects ... -
In vitro study of human lymphocytes cytological and biochemical effects by zingiberene
(Taylor & Francis Inc, 2014)In this study, the cytological and biochemical effects of zingiberene (ZBN) on human lymphocytes cultures were investigated. the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and lactate dehydrogenase ... -
Increased bladder wall thickness in diabetic and nondiabetic women with overactive bladder
(Korean Continence Soc, 2013)Purpose: Bladder wall thickness has been reported to be associated with overactive bladder (OAB) in women. Diabetic women have an increased risk for OAB syndrome and may have an increased risk for bladder wall thickness. ... -
Increased circulating soluble CD40 levels in patients with slow coronary flow phenomenon: an observational study
(2013)Amaç: Koroner yavaş akım (KYA) epikardiyal koroner arterlerin obstrüktif hastalık olmaksızın yavaş dolması ile karakterize bir durumdur. CD40/ CD40 ligandı (CD40L) sistemi artmış enflamasyon ve protrombotik yatkınlık ... -
Increased serum resistin levels in patients with coronary slow-flow phenomenon
(Urban und Vogel GmbH, 2013)Background. Slow coronary flow (SCF) is an angiographic finding characterized by delayed opacification of the epicardial coronary arteries without obstructive coronary disease. Resistin, an adipocytokine, plays a major ... -
Increased YKL-40 levels in patients with isolated coronary artery ectasia: an observational study
(2013)Amaç: YKL-40, yeni bir yerel enflamasyon biyobelirteci, aterosklerotik plaklar içerisinde makrofajlar tarafından salınırlar. Koroner arter ektazisi (KAE) etyopatogenezisi kesin olarak ortaya konulmamış klinik bir antitedir. ... -
Infliximab modulates cisplatin-induced hepatotoxicity in rats
(Galenos Publ, 2016)Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ... -
Influence of infliximab pretreatment on ischemia/reperfusion injury in rat intestine
(Via Medica, 2014)The Pringle maneuver is used in hepatic surgery to prevent blood loss but is associated with ischemia-reperfusion injury. To investigate the effect of infliximab on inflammation and apoptosis in rat intestinal mucosa during ... -
Influences of periodontitis on hippocampal inflammation, oxidative stress, and apoptosis in rats
(Wiley, 2021)Background and aim The hippocampus, which has a central role in cognitive and behavioral activities, is one of the most sensitive parts of the brain to systemic inflammatory diseases. This animal study aims to comprehensively ... -
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab
(Taylor & Francis Ltd., 2022)Methotrexate (MTX) has been in use for the treatment of rheumatoid arthritis (RA), psoriasis, and cancer since 1948. Its toxic side effects on tissues and organs have been well documented but splenotoxicity has not been ... -
Inhibition of O6-methylguanine-DNA-methyltransferase (MGMT) by lomeguatrib reduces multiple myeloma cell viability and impairs DNA repair in MGMT-proficient cells
(Wiley, 2024)The function of direct DNA damage repair protein, namely MGMT in MM, and the impact of MGMT on melphalan treatment remains unclear. We showed a significantly higher MGMT mRNA expression in CD138+ myeloma cells than in ...
