Yazar "Şehitoğlu, İbrahim" için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period
Şehitoğlu, İbrahim; Tümkaya, Levent; Kalkan, Yıldıray; Bedir, Recep; Cüre, Medine Cumhur; Zorba, Orhan Ünal; Cüre, Erkan; Yüce, Süleyman (Iniestares, S.A., 2015)OBJECTIVES: Electromagnetic radiation (ER) emitted from cell phones may exert a detrimental influence on human health and may affect the man reproductive system. We aimed to study the biological and morphological effects ... -
Biochemical, histopathological and immunohistochemieal evaluation of the protective and therapeutic effects of thymoquinone against ischemia and ischemia/reperfusion injury in the rat ovary
Ural, Ülkü Mete; Tekin, Yeşim Bayoğlu; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Cüre, Medine Cumhur (Karger, 2016)Aim: To evaluate the antioxidant effects of thymoquinone (TQ) and to investigate the biochemical, histopathological and immunohistochennical changes in experimental rat ovarian torsion. Methods: A total of 48 female adult ... -
Clinical and histopathologic differential diagnosis of venous malformation of the uterine cervix
Üstüner, Işık; Bedir, Recep; Üstüner, Pelin; Bağcı, Pelin; Güçer, Hasan; Şehitoğlu, İbrahim; Fedakar, Özgür; Güvendağ, Seda (Lippincott Williams & Wilkins, 2013)Objective. Venous malformations of the uterine cervix are extremely rare. Most lesions are asymptomatic and incidental, but sometimes, they may present with abnormal and/or intractable vaginal bleeding. the study aimed to ... -
The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development
Bedir, Recep; Tümkaya, Levent; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Yılmaz, Adnan; Şahin, Osman Zikrullah (Informa Healthcare, 2015)Background: the aim of this study was to investigate the effects of exposure to a 900-MHz electromagnetic field (EMF) produced by mobile phones on the renal development of prenatal rats. Histopathological changes and ... -
Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats
Yücel, Ahmet Fikret; Pergel, Ahmet; Aydın, İbrahim; Alaçam, Hasan; Karabıçak, İlhan; Kesicioğlu, Tuğrul; Tümkaya, Levent; Kalkan, Yıldıray; Arslan, Zakir; Şehitoğlu, İbrahim; Şahin, Dursun Ali (E-Century Publishing Corp, 2015)This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ... -
The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats
Erkut, Adem; Tümkaya, Levent; Balık, Mehmet Sabri; Kalkan, Yıldıray; Güvercin, Yılmaz; Yılmaz, Adnan; Yüce, Süleyman; Cüre, Erkan; Şehitoğlu, İbrahim (Acta Cirurgica Brasileira, 2016)PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation ... -
Effects of 900 MHz electromagnetic field on prenatal locomotor development in rats
Balık, Mehmet Sabri; Tümkaya, Levent; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Yılmaz, Adnan; Balık, Gülşah; Erkut, Adem; Güvercin, Yılmaz; Mercantepe, Tolga (E-Century Publishing Corp, 2019)Introduction: the present study investigated the effects of 900 MHz electromagnetic field (EMF) on locomotor system development in pregnant rats. Materials and methods: Following impregnation, the rats were divided into a ... -
Epidermoid cyst on the nipple: a rare location
Dilek, Nursel; Dilek, Aziz Ramazan; Saral, Yunus; Şehitoğlu, İbrahim (Wiley-Blackwell, 2014)A 27-year-old woman presented to our department with a small, painful, white, soft tissue growth on the nipple of her right breast. -
High dose zoledronic acid increases ischemia-reperfusion damage of the liver
Aydın, İbrahim; Şehitoğlu, İbrahim; Özer, Emel; Kalkan, Yıldıray; Tümkaya, Levent; Cüre, Medine Cumhur; Cüre, Erkan (Verduci Publisher, 2021)OBJECTIVE: Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, has been reported to exhibit a protective effect against cancers and prevent bone fractures. It also induces apoptosis by increasing proinflammatory ... -
Is adalimumab protective in ischemia‐reperfusion injury in lung?
Kurt, Aysel; Tümkaya, Levent; Kalkan, Yıldıray; Türüt, Hasan; Cüre, Medine Cumhur; Cüre, Erkan; Şehitoğlu, İbrahim; Bilgin, Hacer; Usta, Mustafa (Mashhad University of Medical Sciences, 2015)Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I?R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor?alpha (TNF??) inhibitor agent. We aimed ... -
A novel model approach for esophageal burns in rats: a comparison of three methods
Kalkan, Yıldıray; Tümkaya, Levent; Akdoğan, Remzi Adnan; Yücel, Ahmet Fikret; Tomak, Yakup; Şehitoğlu, İbrahim; Pergel, Ahmet; Kurt, Aysel (Sage Publications Inc, 2015)Background: Corrosive esophageal injury causes serious clinical problems. We aimed to create a new experimental esophageal burn model using a single catheter without a surgical procedure. Materials and methods: We conducted ... -
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
Kurt, Aysel; Tümkaya, Levent; Yüce, Süleyman; Türüt, Hasan; Cüre, Medine Cumhur; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Pusuroğlu, Gökhan; Cüre, Erkan (Mashhad Univ Med Sciences, 2016)Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ... -
Protective effect of infliximab against carbon tetrachloride-induced hepatotoxicity
Şehitoğlu, İbrahim; Tümkaya, Levent; Bedir, Recep; Özer, Ender; Cüre, Medine Cumhur; Yüce, Süleyman; Kalkan, Yıldıray; Cüre, Erkan (Begell House Inc, 2015)Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ... -
Protective effects of infliximab on lung injury induced by methotrexate
Kurt, Aysel; Tümkaya, Levent; Türüt, Hasan; Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Şehitoğlu, İbrahim; Acıpayam, Ahmet (Elsevier Espana Slu, 2015)Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ... -
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
Erkut, Adem; Cüre, Medine Cumhur; Kalkan, Yıldıray; Balık, Mehmet Sabri; Güvercin, Yılmaz; Yaprak, Esra; Yüce, Süleyman; Şehitoğlu, İbrahim; Cüre, Erkan (Verduci Publisher, 2016)OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ... -
Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity
Mercantepe, Tolga; Kalkan, Yıldıray; Tümkaya, Levent; Şehitoğlu, İbrahim; Mercantepe, Filiz; Yıldırmış, Sermet (Wroclaw Medical Univ, 2018)Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ... -
Relationships between C-kit expression and mean platelet volume in benign, preneoplastic and neoplastic endometrium
Şehitoğlu, İbrahim; Bedir, Recep; Ural, Ülkü Mete; Güçer, Hasan; Yurdakul, Cüneyt; Cüre, Medine Cumhur; Cüre, Erkan; Yüce, Süleyman; Şahin, Figen Kır (Asian Pacific Organization for Cancer Prevention, 2015)Background: c-Kit is a proto-oncogene that encodes a tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker for demonstrating thrombocyte function. We aimed to investigate whether c-kit is expressed ... -
Taenıa ınfestatıon ın the appendıx: a case report
Çiçek, Ayşegül Çopur; Şehitoğlu, İbrahim; Ekşi, Saliha (Southeast Asian Ministers Educ Organization, 2013)Taenia saginata is a zoonotic cestode causing taeniasis. Taeniasis refers to the intestinal infection with the adult stage of this tapeworm. An association between teaniasis and acute appendicitis is uncommon. We present ... -
Topiramate has protective effect on renal injury
Cüre, Medine Cumhur; Cüre, Erkan; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İlkyaz; Kırbaş, Aynur; Efe, Hasan; Şehitoğlu, İbrahim; Yüce, Süleyman (Comenius Univ, 2015)Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ... -
Zoledronic acid aggravates kidney damage during ischemia reperfusion injury in rat
Şehitoğlu, İbrahim; Tümkaya, Levent; Bedir, Recep; Kalkan, Yıldıray; Cüre, Medine Cumhur; Yücel, Ahmet Fikret; Zorba, Orhan Ünal; Yüce, Süleyman; Cüre, Erkan (Begell House Inc., 2015)Introduction: Zoledronic acid (ZA), a bisphosphonate, increases the levels of cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-?), and reactive oxygen species (ROS) in subjects without cancer. ...